scholarly journals Dietary Calcium Intake and Calcium Supplementation in Hungarian Patients with Osteoporosis

2013 ◽  
Vol 2013 ◽  
pp. 1-8
Author(s):  
Gábor Speer ◽  
Pál Szamosujvári ◽  
Péter Dombai ◽  
Katalin Csóré ◽  
Kinga Mikófalvi ◽  
...  

Purpose. Adequate calcium intake is the basis of osteoporosis therapy—when this proves insufficient, even specific antiosteoporotic agents cannot exert their actions properly.Methods. Our representative survey analyzed the dietary intake and supplementation of calcium in 8033 Hungarian female and male (mean age: 68 years) (68.01 (CI95: 67.81–68.21)) patients with osteoporosis.Results. Mean intake from dietary sources was665±7.9 mg (68.01 (CI95: 67.81–68.21)) daily. A significant positive relationship could be detected between total dietary calcium intake and lumbar spine BMD (P=0.045), whereas such correlation could not be demonstrated with femoralT-score. Milk consumption positively correlated with femur (P=0.041), but not with lumbar BMD. The ingestion of one liter of milk daily increased theT-score by 0.133. Average intake from supplementation was558±6.2 mg (68.01 (CI95: 67.81–68.21)) daily. The cumulative dose of calcium—from both dietary intake and supplementation—was significantly associated with lumbar (r=0.024,P=0.049), but not with femur BMD (r=0.021,P=0.107). The currently recommended 1000–1500 mg total daily calcium intake was achieved in 34.5% of patients only. It was lower than recommended in 47.8% of the cases and substantially higher in 17.7% of subjects.Conclusions. We conclude that calcium intake in Hungarian osteoporotic patients is much lower than the current recommendation, while routinely applied calcium supplementation will result in inappropriately high calcium intake in numerous patients.

Author(s):  
Feitong Wu ◽  
Katja Pahkala ◽  
Markus Juonala ◽  
Suvi P. Rovio ◽  
Matthew A. Sabin ◽  
...  

2015 ◽  
Vol 10 (1) ◽  
pp. 42
Author(s):  
Ciro Manzo ◽  
Maria Teresa Russo

Inadequate intake of calcium via the diet is very common in patients taking drugs for osteoporosis. We have evaluated 302 consecutive elderly patients (68.6 median age) attending our Rheumatological and Orthopedic Outpatient Clinics using a questionnaire for evaluation of dietary calcium intake. Two hundred and forty of these had a questionnaire score 7 in 205/240 after an average period of 3-6 months. In the 35 patients in which this was not possible, the exact knowledge of calcium dietary intake (poor or absent) has allowed a tailored calcium supplementation.


Nutrients ◽  
2019 ◽  
Vol 11 (7) ◽  
pp. 1454 ◽  
Author(s):  
Jaak Jürimäe ◽  
Evelin Mäestu ◽  
Eva Mengel ◽  
Liina Remmel ◽  
Priit Purge ◽  
...  

The aim was to investigate the possible association of dietary calcium intake with adiposity, insulin resistance, and adipocytokine values in adolescent boys. In this cross-sectional study, participants were 123 adolescent boys aged 13–15 years, who were divided into tertiles according to their dietary calcium intake. Dietary calcium intake was assessed using three 24 h dietary recalls. In addition, energy intake, body composition, physical activity (PA), and blood biochemical values were also measured. Mean body fat%, fat mass (FM), trunk FM, trunk fat%, and leptin differed between high and low tertiles of calcium intake after adjustment for age, pubertal stage, and PA. For the entire cohort, mean calcium intake was 786 ± 380 mg/day and was related to body mass index (BMI), FM, and trunk fat% but not to insulin resistance or adipocytokine values after adjusting for possible confounders. In addition, only 15.4% of the participants obtained or exceeded their mean dietary calcium intake requirements. These subjects who met their dietary calcium intake had significantly lower body fat% in comparison with subjects not meeting their dietary calcium intake. Odds ratio of being in the highest tertile of FM, trunk FM, and trunk fat% was 3.2–4.4 (95% confidence interval 1.19–12.47; p < 0.05) times higher for boys in low calcium intake tertile, compared to those boys in high calcium intake tertile. In conclusion, dietary calcium intake is inversely associated with total body and abdominal adiposity values in a specific group of healthy male adolescents with different body mass values.


1994 ◽  
Vol 72 (8) ◽  
pp. 937-944 ◽  
Author(s):  
David A. McCarron ◽  
Daniel Hatton ◽  
Jean-Baptiste Roullet ◽  
Chantal Roullet

The association between dietary calcium intake, calcium metabolism, and blood pressure form the basis of this review. Epidemiologic data consistently show an inverse relationship between dietary calcium and blood pressure. Clinical trials of calcium supplementation have not been as consistent in outcome. Approximately two-thirds of the supplementation studies have found a beneficial effect of calcium on blood pressure. The lack of consistency in outcome from the clinical trials relative to the epidemiological literature may be related to calcium intake. The epidemiological literature indicates an inverse relationship between calcium intake and blood pressure, with those individuals with the lowest calcium intake (< 700 mg/day) having the highest blood pressure. Clinical studies utilizing patients with high baseline calcium levels (> 700 mg/day) may not see an effect of calcium supplementation on blood pressure because of a ceiling effect. Supplemental calcium appears to correct a defect in calcium handling characterized by a renal calcium leak, increased circulating parathroid hormone, and increased intracellular calcium levels. In part, the deficit in cellular calcium homeostasis may be a consequence of abnormal calmodulin activity. Specifically, it appears that calmodulin activity is diminished in experimental hypertension and that increasing dietary calcium may improve calmodulin activity in the spontaneously hypertensive rat. The deficit in calmodulin activity has the potential to interfere with a number of cellular processes crucial to the regulation of cell function and maintenance of appropriate vascular tone. It is concluded that additional research should be directed toward understanding the ramifications of altered calmodulin activity in hypertension and the influence that dietary calcium can have on the activity of calmodulin.Key words: hypertension, dietary Ca2+, calmodulin, Ca2+ metabolism, calcium channel blockers.


1998 ◽  
Vol 67 (6) ◽  
pp. 1273-1278 ◽  
Author(s):  
P Fardellone ◽  
M Brazier ◽  
S Kamel ◽  
J Guéris ◽  
A M Graulet ◽  
...  

1996 ◽  
Vol 6 (S1) ◽  
pp. 270-270
Author(s):  
S. Kamel ◽  
M. Brazier ◽  
P. Fardellone ◽  
Y. Rigault ◽  
JP Berrou ◽  
...  

2004 ◽  
Vol 80 (5) ◽  
pp. 1422-1427 ◽  
Author(s):  
Christian Mølgaard ◽  
Birthe L Thomsen ◽  
Kim F Michaelsen

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