Ameloblastic Fibroma: A Rare Entity of the Mandible

2019 ◽  
Vol 152 (Supplement_1) ◽  
pp. S48-S48
Author(s):  
Sakshi Sakshi ◽  
Riya Kuklani
Keyword(s):  
Cell Layer ◽  
World Health ◽  
Tissue Formation ◽  
Hard Tissue ◽  
Radiological Findings ◽  
Unerupted Tooth ◽  
Odontogenic Epithelium ◽  
Ameloblastic Fibroma ◽  
Ameloblastic Fibrosarcoma ◽  
Health Organization

Abstract Ameloblastic fibroma (AF) is an uncommon benign odontogenic true mixed tumor comprising neoplastic epithelial and mesenchymal tissues. It constitutes only approximately 2% of odontogenic tumors and is defined by the World Health Organization (WHO) as “neoplasm composed of proliferating odontogenic epithelium embedded in cellular ectomesenchymal tissue that resembles the dental papilla and epithelial strands and varying degrees of inductive changes and dental hard tissue formation.” The tumor is most common in the first and second decades of life with a slight male predilection. The most common site is the posterior mandible and 75% of the cases are associated with an unerupted tooth. Radiologically, it may present as a unilocular or multilocular lesion. The treatment of choice could range from aggressive curettage for a small unilocular lesion to wide local excision for a large multilocular lesion. The prognosis is usually good, with a recurrence rate of approximately 20%. Here we present a case of a 13-year-old male with a multilocular expansile cystic lesion associated with nonvital tooth 20 and tooth 21 since 2016. An incisional biopsy was performed and the microscopic examination revealed small masses of cellular fibrous and myxoid connective tissue containing long narrow cords of odontogenic epithelium. The odontogenic islands were basophilic with peripheral nuclear palisading of the basal cell layer, consistent with an ameloblastic fibroma. Complete curettage was performed and the patient is being followed up with no recurrence since 2 months. We reviewed the literature with regard to clinical, histopathological, and radiological findings and reached the conclusion that malignant transformation of ameloblastic fibroma into ameloblastic fibrosarcoma is uncommon but well documented. AF needs to be distinguished from ameloblastoma and ameloblastic fibrosarcoma, since these two tumors can be locally invasive and have greater potential for recurrence than ameloblastic fibroma.

scholarly journals Adenomatoid Odontogenic Tumour - The Master of Disguise

2021 ◽  
Vol 10 (11) ◽  
pp. 835-838
Author(s):  
Shreyas N. Shah ◽  
Falguni Patel ◽  
Vandana Shah
Keyword(s):  
World Health ◽  
Odontogenic Tumour ◽  
Odontogenic Tumours ◽  
Facial Defect ◽  
Odontogenic Epithelium ◽  
Histological Variants ◽  
Epithelial Tumour ◽  
Adenomatoid Odontogenic Tumour ◽  
Health Organization ◽  
Slow Growing

Adenomatoid odontogenic tumour, truly coined as one of the masters of disguise of orofacial pathologies, was first reported in the literature by Steen Lands.1 Philipson and Brin used the terminology adenomatoid odontogenic tumour for this pathology with its commonly accepted abbreviation AOT.2 Later on, adenomatoid odontogenic tumour (AOT) name was accepted by the World Health Organization (WHO) in 1971. In 2005, WHO revealed the histological variants of the adenomatoid odontogenic tumour and classified it as a tumour comprised of odontogenic epithelium showing various patterns in histopathologic view within a mature connective tissue stroma.3 It is seldom noticed neoplasm which comprises only 3 % of all the odontogenic tumours. It was commonly found in the maxilla with female predilection and mostly in association with impacted canines.4-6 Adenomatoid odontogenic tumour is an odontogenic epithelial tumour usually seen in females in their second decade of life. The tumour is slow growing in nature which eventually results in painless expansion of jaw. The maxilla is commonly affected than mandible. Being benign in nature, most of the AOT cases usually got treated with conservative surgical enucleation but the greater size of tumour can leave behind an oro-facial defect. To prevent such type of incident, it is important to diagnose them early and treat accordingly. Herewith, we are presenting a case report of adenomatoid odontogenic tumour of mandible in a male patient.

scholarly journals Ameloblastic fibro-odontoma associated with paresthesia of the chin and lower lip in a 12-year-old girl

2019 ◽  
Vol 7 ◽  
pp. 2050313X1987064
Author(s):  
Dereen Mohammed Saeed ◽  
Suman Setty ◽  
Michael R Markiewicz ◽  
Robert J Cabay
Keyword(s):  
Panoramic Radiography ◽  
Third Molar ◽  
Mandibular Canal ◽  
Tissue Formation ◽  
Hard Tissue ◽  
Lower Lip ◽  
Odontogenic Epithelium ◽  
Mandibular Third Molar ◽  
Close Proximity ◽  
The Right

Ameloblastic fibro-odontoma is a rare, benign, and slowly growing neoplasm of the jaw composed of proliferating odontogenic epithelium in ectomesenchymal tissue along with dental hard tissue formation. Herein, we describe a case of an ameloblastic fibro-odontoma in 12-year-old female with paresthesia of the chin and lower lip. Panoramic radiography showed a radio-opacity in the right posterior mandible near the mandibular canal and associated with the right mandibular third molar. Histologically, the lesion contained epithelial and mesenchymal odontogenic components in close proximity to odontoma-like elements. Enucleation and curettage of the affected site in the mandible resulted in resolution of the paresthesia postoperatively.

Rare giant cell ependymoma in an octogenarian

2006 ◽  
Vol 105 (6) ◽  
pp. 908-911 ◽  
Author(s):  
Patrick B. Cooper ◽  
Matthew Katus ◽  
Leon Moores ◽  
Dennis Geyer ◽  
James G. Smirniotopoulos ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Giant Cell ◽  
Unusual Case ◽  
Clinical Presentation ◽  
Surgical Intervention ◽  
Relevant Literature ◽  
World Health ◽  
Radiological Findings ◽  
The World ◽  
Health Organization

✓Ependymomas are glial tumors that occur most often in children. In adults, ependymomas most often appear in the spinal cord. The World Health Organization recognizes several rare ependymoma subtypes, including the giant cell ependymoma of the terminal filum. The authors describe an unusual case of a posterior fossa giant cell ependymoma in an 89-year-old man presenting with vertigo and disequilibrium. Only seven cases of this tumor have been reported in the literature to date. The authors discuss the clinical presentation, radiological findings, pathological considerations, and surgical intervention in this patient and review the relevant literature.

scholarly journals Erupting Compound Odontome - A Case Report

2021 ◽  
Vol 10 (18) ◽  
pp. 1361-1364
Author(s):  
Shreyas N. Shah ◽  
Falguni Patel
Keyword(s):  
World Health Organization ◽  
World Health ◽  
Radiographic Evaluation ◽  
Dental Tissue ◽  
Odontogenic Tumours ◽  
Dental Tissues ◽  
Odontogenic Epithelium ◽  
Complex Odontoma ◽  
Health Organization ◽  
Compound Odontoma

Odontomas are asymptomatic, benign odontogenic tumours comprised of dental tissue. Most of the cases usually get detected on routine radiographic evaluation. Odontoma can be classified according to morphology in two different variants, compound odontoma showing anatomic similarity or miniature version of the tooth and complex odontoma having irregular masses with different type of dental tissues. Early detection of such type of silent lesion is mandatory to rule out certain silent but aggressive pathologies. Here, we present a case of erupting compound odontoma of maxillary area in 15-year-old male patient. Development of tooth is a result of complicated interaction between ectodermal and ecto mesenchymal tissue. Sometimes the remnants of such tissues are left behind in the jaw after development and eruption of tooth, which can become a source of development of odontogenic lesions later on.1 As revealed by World Health Organization (WHO), Odontogenic tumours can be classified in three different categories according to their histopathological form.2 1. Odontogenic tumours which develop from odontogenic epithelium without involvement of odontogenic ectomesenchyme, 2. Odontogenic tumours which develop from odontogenic epithelium with involvement of odontogenic ectomesenchyme, with or without formation of dental hard tissue and 3. Odontogenic tumours which develop from odontogenic ectomesenchyme with or without involvement of odontogenic epithelium.2 For such lesions “Odontoma” word was initially given by Paul Broca in 1866, who revealed the term as tumour occurred by the overgrowth of entire dental tissue. The growth of absolutely differentiated epithelial cells as functional ameloblast and mesenchymal cells as functional odontoblast can give rise to a different developmental anomaly coined as Odontomas.3 According to their behaviour and composition, odontomas can be considered as malformations or hamartomas rather than a true neoplasm. 4,5,6 In 2005, World Health Organization (WHO) classified two variants of odontomas, 1. Compound odontomas, which typically appears as unilocular lesions containing multiple radiopaque, tiny tooth like structures commonly known as denticles; and 2. Complex odontomas, which is comprised of an irregular mass of soft and hard dental tissues.

scholarly journals Round Blue Cell Tumor arising in the Background of Ameloblastic Fibrosarcoma

2013 ◽  
Vol 4 (2) ◽  
pp. 83-85
Author(s):  
Raza Hussain ◽  
Asif Loya ◽  
Arif Jamshed ◽  
Usman Hassan
Keyword(s):  
Malignant Neoplasm ◽  
Cell Tumor ◽  
World Health ◽  
Blue Book ◽  
Inferior Margin ◽  
Neck Tumors ◽  
Blue Cell ◽  
Ameloblastic Fibrosarcoma ◽  
Health Organization ◽  
Round Blue Cell Tumor

ABSTRACT World Health Organization (WHO) blue book of head and neck tumors reports 64 cases of ameloblastic fibrosarcoma and 14 cases of ameloblastic fibrodentinosarcoma/fibro-odontosarcoma. We present a unique case that does not fit into any of the WHO classified odontogenic sarcomas. The patient presented in 2006 with a densely sclerotic lesion arising from the left sphenoid bone, displacing the orbital contents and extending up to the inferior margin of the maxillary sinus. He was treated with left maxillectomy orbital exenteration. He relapsed 6 years later, salvage surgery was unsuccessful and subsequent care was supportive. Histologically the malignant neoplasm showed follicles comprising of peripheral columnar cells lined up in palisaded fashion with hyperchromatic nuclei displaced away from basement membrane. Center of the follicles comprised of spindle-shaped cells resembling stellate reticulum. Intervening areas showed fibrosarcomatous areas. Other areas revealed predominant sheets of round cells having hyperchromatic nuclei, inconspicuous nucleoli and scant cytoplasm. These round cells revealed strong membranous positivity for CD99. How to cite this article Hussain R, Hassan U, Jamshed A, Loya A. Round Blue Cell Tumor arising in the Background of Ameloblastic Fibrosarcoma. Int J Head Neck Surg 2013;4(2): 83-85.

Obstacles to Claiming Permanence and Injury-Relatedness for “Posttraumatic” Headache

2009 ◽  
Vol 14 (3) ◽  
pp. 3-6
Author(s):  
Robert J. Barth
Keyword(s):  
Complete Recovery ◽  
World Health ◽  
Related Factors ◽  
Posttraumatic Headache ◽  
Sixth Edition ◽  
Causative Relationship ◽  
Short Period ◽  
The One ◽  
Health Organization ◽  
Subjective Reports

Abstract “Posttraumatic” headaches claims are controversial because they are subjective reports often provided in the complex of litigation, and the underlying pathogenesis is not defined. This article reviews principles and scientific considerations in the AMAGuides to the Evaluation of Permanent Impairment (AMA Guides) that should be noted by evaluators who examine such cases. Some examples in the AMA Guides, Sixth Edition, may seem to imply that mild head trauma can cause permanent impairment due to headache. The author examines scientific findings that present obstacles to claiming that concussion or mild traumatic brain injury is a cause of permanent headache. The World Health Organization, for example, found a favorable prognosis for posttraumatic headache, and complete recovery over a short period of time was the norm. Other studies have highlighted the lack of a dose-response correlation between trauma and prolonged headache complaints, both in terms of the frequency and the severity of trauma. On the one hand, scientific studies have failed to support the hypothesis of a causative relationship between trauma and permanent or prolonged headaches; on the other hand, non–trauma-related factors are strongly associated with complaints of prolonged headache.

Sixth Edition: the New Standard

2008 ◽  
Vol 13 (1) ◽  
pp. 1-12
Author(s):  
Christopher R. Brigham ◽  
Robert D. Rondinelli ◽  
Elizabeth Genovese ◽  
Craig Uejo ◽  
Marjorie Eskay-Auerbach
Keyword(s):  
Review Process ◽  
Peer Review Process ◽  
World Health ◽  
International Classification Of Functioning ◽  
Revision Process ◽  
Sixth Edition ◽  
Impairment Ratings ◽  
Health Organization ◽  
Impairment Severity

Abstract The AMA Guides to the Evaluation of Permanent Impairment (AMA Guides), Sixth Edition, was published in December 2007 and is the result of efforts to enhance the relevance of impairment ratings, improve internal consistency, promote precision, and simplify the rating process. The revision process was designed to address shortcomings and issues in previous editions and featured an open, well-defined, and tiered peer review process. The principles underlying the AMA Guides have not changed, but the sixth edition uses a modified conceptual framework based on the International Classification of Functioning, Disability, and Health (ICF), a comprehensive model of disablement developed by the World Health Organization. The ICF classifies domains that describe body functions and structures, activities, and participation; because an individual's functioning and disability occur in a context, the ICF includes a list of environmental factors to consider. The ICF classification uses five impairment classes that, in the sixth edition, were developed into diagnosis-based grids for each organ system. The grids use commonly accepted consensus-based criteria to classify most diagnoses into five classes of impairment severity (normal to very severe). A figure presents the structure of a typical diagnosis-based grid, which includes ranges of impairment ratings and greater clarity about choosing a discreet numerical value that reflects the impairment.

The Historical Development of Burden of Treatment Compliance

2014 ◽  
Vol 19 (5) ◽  
pp. 13-15
Author(s):  
Stephen L. Demeter
Keyword(s):  
Internal Medicine ◽  
Treatment Compliance ◽  
World Health ◽  
International Classification Of Functioning ◽  
Sixth Edition ◽  
Burden Of Treatment ◽  
Specific Goal ◽  
Surrogate Measure ◽  
Health Organization

Abstract A long-standing criticism of the AMA Guides to the Evaluation of Permanent Impairment (AMA Guides) has been the inequity between the internal medicine ratings and the orthopedic ratings; in the comparison, internal medicine ratings appear inflated. A specific goal of the AMA Guides, Sixth Edition, was to diminish, where possible, those disparities. This led to the use of the International Classification of Functioning, Disability, and Health from the World Health Organization in the AMA Guides, Sixth Edition, including the addition of the burden of treatment compliance (BOTC). The BOTC originally was intended to allow rating internal medicine conditions using the types and numbers of medications as a surrogate measure of the severity of a condition when other, more traditional methods, did not exist or were insufficient. Internal medicine relies on step-wise escalation of treatment, and BOTC usefully provides an estimate of impairment based on the need to be compliant with treatment. Simplistically, the need to take more medications may indicate a greater impairment burden. BOTC is introduced in the first chapter of the AMA Guides, Sixth Edition, which clarifies that “BOTC refers to the impairment that results from adhering to a complex regimen of medications, testing, and/or procedures to achieve an objective, measurable, clinical improvement that would not occur, or potentially could be reversed, in the absence of compliance.

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