scholarly journals Hope-Simpson's Progressive Immunity Hypothesis as a Possible Explanation for Herpes Zoster Incidence Data

2013 ◽  
Vol 177 (10) ◽  
pp. 1134-1142 ◽  
Author(s):  
Giorgio Guzzetta ◽  
Piero Poletti ◽  
Emanuele Del Fava ◽  
Marco Ajelli ◽  
Gian Paolo Scalia Tomba ◽  
...  
2018 ◽  
Vol 69 (2) ◽  
pp. 341-344 ◽  
Author(s):  
Rafael Harpaz ◽  
Jessica W Leung

Abstract Historic herpes zoster incidence trends in US adults have been hard to interpret. Using administrative databases, we extended previous descriptions of these trends through 2016. We observed an age-specific transition, with ongoing increases among younger adults but deceleration in older adults. The patterns are not readily explained.


2019 ◽  
Vol 22 ◽  
pp. S656
Author(s):  
D. van Oorschot ◽  
H. Vroling ◽  
E. Bunge ◽  
B. Briquet ◽  
J. Diaz-Decaro ◽  
...  

2021 ◽  
Author(s):  
Jialing Lin ◽  
Timothy Dobbins ◽  
James G Wood ◽  
Carla Bernardo ◽  
Nigel P Stocks ◽  
...  

Summary Objectives: To evaluate the impact of the National Herpes Zoster (zoster) Immunisation Program in Australia on zoster incidence. Methods: Ecological analysis of zoster incidence related to timing of implementation of the national program in vaccine-targeted (70-79 years) and non-targeted age groups (60-69 and 80-89 years) during January 2013-December 2018 was estimated using interrupted time-series analyses. Results: Prior to program commencement (Jan 2013 to Oct 2016) in patients aged 60-69, 70-79 and 80-89 years, incidence was mostly stable averaging respectively 7.2, 9.6 and 10.8 per 1000 person-years. In the two years following program commencement, incidence fell steadily in those aged 70-79 years, with an estimated decrease of 2.25 (95% CI: 1.34, 3.17) per 1000 person-years per year, with women having a greater decrease than men (2.83 versus 1.68, p-interaction<0.01). In the two non-vaccine-program-targeted age groups there was no evidence of reduction in zoster incidence: 60-69 years, 0.46 (95% CI: -0.46, 1.38) and 80-89 years, 0.11 (95% CI: -1.64, 1.87). Conclusions: Two years after implementation, an estimated 7000 zoster cases were prevented through the national program. With known waning vaccine efficacy, continued surveillance is needed to ensure these early reductions in incidence are sustained.


Author(s):  
Desmond Curran ◽  
Andrea Callegaro ◽  
Kyle Fahrbach ◽  
Binod Neupane ◽  
Hilde Vroling ◽  
...  

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