560 Case Report: A Very Rare Case of Incidentaloma of a Large Adrenal Cavernous Haemangioma

2021 ◽  
Vol 108 (Supplement_6) ◽  
Author(s):  
Y Chua ◽  
S Quake ◽  
K Prasad ◽  
W El-Saify

Abstract Introduction Incidentaloma are asymptomatic and unanticipated adrenal tumours found on radiological imaging for unrelated diagnostic inquiries. Adrenal cavernous haemangioma is a rare, differentiated and benign tumour arising from the endothelial layer of blood vessels. This is a rare phenomenon with only 66 cases reported in the literature between 1955 and 2018. Case Details This is a case of a 79-year-old Caucasian gentleman who presented in March 2020 with vague abdominal discomfort and anaemia on a background of multiple co-morbidities including in particular, an asymptomatic left 5.6cm adrenal incidentaloma found in 2014. A computed tomography scan of abdomen-pelvis in June 2020 revealed progression in size of the incidentaloma to 20.8cm. Biochemical tests confirmed non-functioning adrenal tumour. The patient underwent open left adrenalectomy, left nephrectomy, splenectomy and distal pancreatectomy. The diagnosis of adrenal cavernous haemangioma was subsequently made on histopathological examination. Post-operatively, our patient made a good physiological recovery. Discussion There are no established diagnostic and treatment guidelines for adrenal cavernous haemangioma. Larger tumours are often treated surgically to exclude malignancies and to prevent potential complications as well as symptom relief. Literature reviews showed that most cases were surgically managed, and diagnoses were made through histology post-operatively. Conclusions Adrenal cavernous haemangioma typically present as incidentalomas which require further investigations. They are very rare non-functioning benign tumours that can be difficult to be differentiated from other adrenal malignancies.

2021 ◽  
Vol 15 (2) ◽  
pp. 106-107
Author(s):  
Swapan Kumar Biswas ◽  
Saiful Islam Khan ◽  
Muhammad Mofazzal Hossain

Isolated gall bladder tuberculosis (GBTB) is exceedingly rare even in an endemic region and is usually found as a GB mass in association with cholelithiasis. Confirmed preoperative diagnosis is very difficult, and most cases are diagnosed after cholecystectomy. We present a case of a 45-years-old woman who came with symptoms of chronic cholecystitis. Computed tomography scan revealed intraluminal gallbladder mass and cholelithiasis. The patient underwent open cholecystectomy and GBTB was diagnosed after histopathological examination. Histopathological examination should be done after all cholecystectomy operations. Faridpur Med. Coll. J. 2020;15(2): 106-107


2013 ◽  
Vol 3 ◽  
pp. 8 ◽  
Author(s):  
Dayananda Kumar Rajanna ◽  
Vaibhav Pandey ◽  
Sujit Janardhan ◽  
Sujatha N Datti

Giant fibroids are known to arise from the uterus, and very rarely from the broad ligament. Large fibroids often undergo hyaline, cystic, and at times, red degeneration. In the present case, cystic degeneration with intervening septations in an adnexal mass raised the suspicion of ovarian neoplasm as the ovaries were not seen as separate from the lesion. The ultrasonographic and contrast-enhanced computed tomographic findings of this case were characteristic of ovarian neoplasm. The differential diagnosis included rare possibility of giant fibroid with cystic degeneration. The diagnosis was confirmed on histopathological examination. The patient underwent excision of the broad ligament fibroid, hysterectomy, and bilateral salpingo-oophorectomy. Magnetic resonance imaging has a role in the diagnosis of such lesions.


2014 ◽  
Vol 2014 ◽  
pp. 1-4 ◽  
Author(s):  
H. Jabir ◽  
N. Tawfiq ◽  
M. Moukhlissi ◽  
M. Akssim ◽  
A. Guensi ◽  
...  

We report a case of adrenal metastasis from colorectal cancer in a 54-year-old woman. Nine months after resection for advanced rectal carcinoma, a computed tomography scan revealed bilateral adrenal metastasis. The level of serum carcinoembryonic antigen was normal. A bilateral adrenalectomy was performed after chemotherapy. Histopathological examination showed adenocarcinoma, compatible with metastasis from the rectal cancer. Adrenal metastasis should be considered in the patients’ follow-up for colorectal cancer.


2018 ◽  
Vol 10 (02) ◽  
pp. 248-250 ◽  
Author(s):  
Aniruddha Saha ◽  
Palash Kumar Mandal ◽  
Anupam Manna ◽  
Kalyan Khan ◽  
Subrata Pal

AbstractWell-differentiated papillary mesothelioma is a rare tumor occurring predominantly in the peritoneum of young women, a few with history of asbestos exposure. A 28-year-old woman presented with ascites and pain abdomen. Ultrasonography and computed tomography scan of the abdomen revealed a mass in the retroperitoneum measuring 15 cm × 12 cm. Histopathological examination along with immunohistochemistry (IHC) confirmed it to be a papillary mesothelioma in the peritoneum. It is difficult to differentiate from more common malignant mesothelioma and papillary adenocarcinoma, which also have poorer prognosis. The difficulty can be resolved by clinico-radiological correlation along with histopathological examination and IHC.


2020 ◽  
Vol 29 (3) ◽  
pp. 209-211
Author(s):  
Ahmad Adib Mohd Nasir ◽  
Mohamed Faisal Abdul Hamid

Here, we describe the case of a 67-year-old man who had been under surveillance for solitary pulmonary nodule for two years and was diagnosed with malignancy via electro-navigational bronchoscopy (ENB). Surveillance computed tomography scan of the thorax showed annual growth increments of the pulmonary nodule. In view of his Brock score showing a 35% probability of malignancy, the patient was subjected to ENB, and metastatic adenocarcinoma from the gastrointestinal tract was diagnosed. ENB was done using a machine on loan from Veran Medical Technologies. The procedure was successful, with no immediate or long-term complications. The diagnosis following histopathological examination was adenocarcinoma, and he was subsequently referred to our oncology unit for further management.


2019 ◽  
Vol 4 (5) ◽  

Although intra cranial meningiomas are usually solid tumors, some are associated with confusing cysts. So, computed tomography scan and conventional magnetic resonance imaging may not easily differentiate these lesions from other tumors frequently associated with cystic or necrotic component as gliomas or metastasis. We report four cases of cystic meningioma in which the diagnosis was not suspected preoperatively because of short clinical history and rapid neurological deterioration. However, a cystic component on imaging studies confused the diagnosis of meningioma with other cyst lesions. Although some authors report that hemorrhage is rare in meningioma, one of our cases was associated with hemorrhage and was histologically grade I meningioma. Total removal of cystic meningioma was our goal and histopathological examination was important to establish the diagnosis after surgery


2016 ◽  
Vol 8 (4) ◽  
Author(s):  
Veronica Carlini ◽  
Valeria Calcaterra ◽  
Noemi Pasqua ◽  
Marinella Guazzotti ◽  
Mario Fusillo ◽  
...  

Few cases of plunging ranulas (PRs) occur during childhood and the lesions are frequently misdiagnosed. Here, a PR in a child is reported along with a literature review. A seven-year-old female complaining of swelling in the midline neck, left-submandibular region, was evaluated. No oral cavity or major salivary glands abnormalities were detected. On palpation, a soft, painless, and fluid-containing mass was observed. The suspicion PR was performed by ultrasound. The diagnosis was confirmed with a histopathological examination. The lesion was removed with a cervical approach, without recurrence. PR is an uncommon condition in children under 10 years of age. Differential diagnosis depends on clinical examination and ultrasonography. A computed tomography-scan and magnetic resonance imaging can be performed if the diagnosis remains uncertain. In pediatrics, the key to success of the treatment may rely on the radical excision of the cyst and sublingual gland, via an intraoral or submandibular approach.


2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Kuniyasu Takagi ◽  
Teppei Kamada ◽  
Yoshinobu Fuse ◽  
Wataru Kai ◽  
Junji Takahashi ◽  
...  

Abstract Background Metastatic neuroendocrine carcinoma has an extremely poor prognosis, and no effective second-line treatment is available. Herein, we describe a case of multiple metastases after primary resection of esophageal neuroendocrine carcinoma successfully treated with nivolumab plus radiotherapy in a short time. Case presentation A man in his 70s presented to our hospital after an abnormality was detected on an upper gastrointestinal series. Upper gastrointestinal endoscopy revealed a type 2 tumor spanning the endothelial cell junction to the abdominal esophagus. Histopathological examination of the biopsy confirmed a diagnosis of esophageal neuroendocrine carcinoma. The patient had no distant metastases. Thoracoscopic esophagectomy with three-field lymph node dissection was performed. Histopathological examination confirmed a diagnosis of esophageal neuroendocrine carcinoma with features of adenoid cystic-like carcinoma and squamoid pattern (pT2 [MP], INF a, ly1, v1 [EVG], pIM0, pDM0, pRM0, pN1 [1/28], M0; Stage II), which was positive for synaptophysin. The postoperative course was good, with no complications. The patient was treated with 100 mg of irinotecan and 100 mg of cisplatin, administered every 4 weeks, as postoperative adjuvant chemotherapy. Grade 3 loss of appetite was observed, and adjuvant chemotherapy was discontinued after four cycles of first-line treatment. A positron emission tomography–computed tomography scan 3 years after surgery showed abnormal uptake in the subaortic, left hilar, and left axillary lymph nodes, and in a mass in the right lung apex. The patient was diagnosed with metastatic esophageal neuroendocrine carcinoma postoperatively. First-line treatment could not be repeated due to toxicity from the initial treatment. Nivolumab (240 mg every 2 weeks) was administered as second-line treatment, and radiotherapy was started (56 Gy delivered in 28 fractions to the local [subaortic and hilar] lymph nodes). After 10 cycles of nivolumab in combination with radiotherapy (56 Gy), a positron emission tomography–computed tomography scan showed disappearance of all lesions. A complete response was achieved. Maintenance therapy (240 mg of nivolumab) was continued. No recurrence has been observed for 42 months. Conclusions We experienced a case in which nivolumab in combination with radiotherapy was effective for metastatic esophageal neuroendocrine carcinoma after primary resection.


Author(s):  
Muniba Mehmood ◽  
Uzair Yaqoob ◽  
Khaled Abdullah Rage ◽  
Hina Khan ◽  
Mujeeb Rehman Abbasi ◽  
...  

Intussusception is an invagination of one segment of the bowel into its adjoining segment. In children, the cause is usually benign, while in adults it is secondary to a mass lesion. Here we present a case in which the preoperative diagnosis of intussusception secondary to colonic mass was made, but no definitive cause was identified by histopathology. A 30-year-old male presented with abdominal pain, altered bowel habits, weight loss, loose motions, bleeding per rectum, and vomiting. The abdomen was distended, firm, mildly tender, and guarded. A vague mass of 15 x 10 cm was palpated on the left upper quadrant. X-ray and ultrasound showed dilated small bowel. A computed tomography scan suggested ileoileal intussusception. Colonoscopy showed a growth at 15 cm of the anal verge. Exploratory laparotomy was performed, showing the presence of ileocolic intussusception with two large perforations. Subtotal colectomy with ileostomy was done. The histopathological examination showed signs of perforation.


Author(s):  
Mahender Singh ◽  
Trilok C. Guleria ◽  
Ramesh K. Azad ◽  
Narender K. Mohindroo

<p>Tuberculosis of the nose is so rare that it has become a forgotten entity among the clinicians. The clinicians fail to diagnose primary nasal TB as symptoms and signs of this specific nasal inflammation mimic other nonspecific nasal inflammatory conditions and therefore, its diagnosis and treatment is often delayed. We came across a case of primary nasal TB in a 65 years old female presented with complaints of nasal obstruction, epistaxis and anosmia since past 3 years. Anterior rhinoscopy showed friable nasal mass in both nasal cavities. Computed tomography scan showed heterogeneously enhancing soft tissue in nasal cavity with destruction of the nasal septum and hard palate. Histopathological examination and GeneXpert confirmed mycobacterium tuberculosis. The patient was put on antituberculous therapy.Nasal endoscopy and tissue biopsy play important role in diagnosis of the disease. GeneXpert test not only has good sensitivity and specificity for the diagnosis of EPTB but also perfectly fits the requirements of the Indian health care setting.</p>


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