scholarly journals Medial Temporal Lobe Contributions to Episodic Future Thinking: Scene Construction or Future Projection?

2016 ◽  
Vol 28 (2) ◽  
pp. 447-458 ◽  
Author(s):  
D J Palombo ◽  
S M Hayes ◽  
K M Peterson ◽  
M M Keane ◽  
M Verfaellie
Cortex ◽  
2020 ◽  
Vol 131 ◽  
pp. 114-122
Author(s):  
Kristin Lynch ◽  
Margaret M. Keane ◽  
Mieke Verfaellie

2015 ◽  
Vol 112 (15) ◽  
pp. 4767-4772 ◽  
Author(s):  
Soyun Kim ◽  
Adam J. O. Dede ◽  
Ramona O. Hopkins ◽  
Larry R. Squire

We evaluated two different perspectives about the function of the human hippocampus–one that emphasizes the importance of memory and another that emphasizes the importance of spatial processing and scene construction. We gave tests of boundary extension, scene construction, and memory to patients with lesions limited to the hippocampus or large lesions of the medial temporal lobe. The patients were intact on all of the spatial tasks and impaired on all of the memory tasks. We discuss earlier studies that associated performance on these spatial tasks to hippocampal function. Our results demonstrate the importance of medial temporal lobe structures for memory and raise doubts about the idea that these structures have a prominent role in spatial cognition.


2012 ◽  
Vol 52 (2-3) ◽  
pp. 77 ◽  
Author(s):  
Mieke Verfaellie ◽  
Elizabeth Race ◽  
Margaret M Keane

2021 ◽  
Author(s):  
David John Hallford ◽  
Samuel Cheung ◽  
Ghofran Baothman ◽  
Jason Weel

Mental simulations of positive future events increase their detail/vividness and plausibility, with effects on cognitive-affective processes such as anticipated and anticipatory pleasure. More recently, spatial details have been distinguished as important in increasing detail and elaborating mental scene construction. Building on this research, this study (N=54; M age=26.9) compared simulations of positive, self-relevant future events spatial details (i.e. people, objects, sequences of actions) with simulations focused on content details. Cross-sectionally at baseline, spatial details uniquely predicted phenomenological characteristics of future events, including anticipatory pleasure. The guided simulations increased detail and vividness, mental imagery, and pre-experiencing in both conditions. The content simulation condition did not increase content details relative to the spatial simulation condition, however, the inverse was true. Relatedly, overall detail and vividness was higher in the spatial condition, as was perceived control. The findings are discussed in relation to future thinking and mental health.


2020 ◽  
Author(s):  
Susan L. Benear ◽  
Elizabeth A. Horwath ◽  
Emily Cowan ◽  
M. Catalina Camacho ◽  
Chi Ngo ◽  
...  

The medial temporal lobe (MTL) undergoes critical developmental change throughout childhood, which aligns with developmental changes in episodic memory. We used representational similarity analysis to compare neural pattern similarity for children and adults in hippocampus and parahippocampal cortex during naturalistic viewing of clips from the same movie or different movies. Some movies were more familiar to participants than others. Neural pattern similarity was generally lower for clips from the same movie, indicating that related content taxes pattern separation-like processes. However, children showed this effect only for movies with which they were familiar, whereas adults showed the effect consistently. These data suggest that children need more exposures to stimuli in order to show mature pattern separation processes.


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