scholarly journals Overview of the Nontyphoidal and Paratyphoidal Salmonella Vaccine Pipeline: Current Status and Future Prospects

2020 ◽  
Vol 71 (Supplement_2) ◽  
pp. S151-S154
Author(s):  
Scott M Baliban ◽  
Ying-Jie Lu ◽  
Richard Malley

Abstract Nontyphoidal Salmonella and Salmonella Paratyphi are responsible for significant morbidity and mortality worldwide. To date, no vaccine has been licensed against these organisms. The development of effective vaccines remains an urgent priority. In this review, the rationale for and current status of various vaccine candidates against S. Paratyphi and nontyphoidal Salmonella are presented, with a focus on the research findings from the 2019 International Conference on Typhoid and Other Invasive Salmonelloses. Additionally, other vaccine candidates that are currently undergoing clinical development are highlighted. Future approaches, which may include antigens that are genetically conserved across Salmonella and confer broad, non–serotype-specific protection, are also discussed.

2015 ◽  
Vol 137 (3) ◽  
Author(s):  
U. Sudeep ◽  
N. Tandon ◽  
R. K. Pandey

Benefits of surface textures for improving the performance behaviors of tribo-contacts are being explored and established by the investigators across the globe. But the consolidated information of findings of such explorations are spread. Therefore, the objective of this paper is to summarize the information available related to the preparation of surface textures and performance outcomes in the presence of surface textures at the concentrated contacts. Mainly, recent research findings and practices followed for the study of friction, wear, lubrication, contact fatigue, vibration, and noise at the generic concentrated contacts in presence of surface textures are reviewed for current status of research in the area and outlining the future prospects.


2019 ◽  
pp. 91-94
Author(s):  
T. M. Lysenko ◽  
V. Yu. Neshatayeva ◽  
Z. V. Dutova

The International conference “Flora and conservation in the Caucasus: history and current state of knowledge” dedicated to the 130-year anniversary of the Perkalsky Arboretum took place at 22–25 of May 2019 in Pyatigorsk (Stavropol Territory) on the base of the Pyatigorsk Museum of local lore and natural history. The participants were from 11 cities of Russia and 7 Republics of the Caucasus and represented 14 institutions. Proceedings of the conference were published by the beginning of the meeting the book of abstracts includes 49 papers on the study of vascular plants, bryophytes, lichens and fungi, plant communities, as well as the protection of rare and endangered species, unique plant communities, and ecological problems in the Caucasus. The following geobotanical topics were highlighted in 13 papers: forest communities (3 reports), meadow and steppe vegetation (2), xeric open forests (2), communities of ecotone areas (1), structure of populations of rare plant species (3), as well as the history and current status of nature protected areas (2). The great emphasis has been focused on the study of floristic composition and plant populations. Thus, the conference showed that very few studies от vegetation are currently carried out in the Caucasus, and a lot of districts are not affected by the research. The greatest attention is paid to forest vegetation while meadow, steppe, alpine heath and xerophytic communities are studied rather poorly. Besides, there are “white spots” — mire, floodplain and aquatic vegetation. In nowadays, when the anthropogenic impact on the plant cover of the Caucasus is intensively increasing, it is especially important to study natural undisturbed communities preserved in protected natural areas. Another important issue is the conservation of the unique vegetation cover of the whole Caucasus. Thus, the study of vegetation of this region opens a wide field for researchers using various methods of modern plant science.


2007 ◽  
Vol 2 (6) ◽  
pp. 607-620 ◽  
Author(s):  
James M Wilkins ◽  
John Loughlin ◽  
Sarah JB Snelling

The second edition of The Oxford Handbook of Personality and Social Psychology captures the history, current status, and future prospects of personality and social psychology—presented not as a set of parallel accounts, but as an integrated perspective on the behavior of persons in social contexts. This handbook combines these two fields in a single integrated volume, offering a unique and generative agenda for psychology. It is dedicated to the proposition that personality and social psychology are best viewed in conjunction with one another and that the synergy to be gained from considering links between the two fields can do much to move both fields forward and to enrich our understanding of human nature. Such interdependence is particularly crucial if one wishes to address the ongoing functioning of persons in their natural environments, where splits between person and situation are not so easily fashioned. The chapters of the Handbook weave together work from personality and social psychology, not only in areas of long-standing concern, but also in newly emerging fields of inquiry, addressing both distinctive contributions and common ground. In so doing, they offer compelling evidence for the power and the potential of an integrated approach to personality and social psychology.


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