Plasma lipid-bound sialic acid and carcinoembryonic antigen in cancer patients.

1981 ◽  
Vol 27 (10) ◽  
pp. 1737-1739 ◽  
Author(s):  
A M Dnistrian ◽  
M K Schwartz
Keyword(s):  
Sialic Acid ◽  
Carcinoembryonic Antigen ◽  
Cancer Patients ◽  
Lipid Extraction ◽  
Plasma Lipid ◽  
Normal Subjects ◽  
Breast Cancer Patients ◽  
Lung Cancer Patients ◽  
Total Lipid Extraction ◽  
The Individual

Abstract We evaluated lipid-bound sialic acid as a "marker" in cancer patients and assessed the individual and combined value of lipid-bound sialic acid and carcinoembryonic antigen determinations in these patients. Plasma was sampled from 62 normal subjects and 125 cancer patients. Lipid-bound sialic acid was determined by the resorcinol method after total lipid extraction and isolation of the sialolipid fraction from plasma. Neither marker was increased in many breast cancer patients. Carcinoembryonic antigen was increased more commonly and to a greater degree in colon cancer patients and seems to be the preferred marker. Both markers were increased in lung cancer patients and their combined evaluation improved the rate of detection. Lipid-bound sialic acid was increased in more patients with leukemias, lymphomas, Hodgkin's disease, and melanomas, suggesting that it may be a useful biochemical marker in these types of cancer.

Salivary Total Sialic Acid Levels Increase in Breast Cancer Patients: A Preliminary Study

2011 ◽  
Vol 7 (5) ◽  
pp. 443-447 ◽  
Author(s):  
Leyla Koc Ozturk ◽  
Ebru Emekli-Alturfan ◽  
Emel Kasikci ◽  
Gokhan Demir ◽  
Aysen Yarat
Keyword(s):  
Breast Cancer ◽  
Sialic Acid ◽  
Cancer Patients ◽  
Breast Cancer Patients ◽  
Total Sialic Acid ◽  
Preliminary Study

Carcinoembryonic Antigen (CEA) in the Follow-Up of Disease-Free Breast Cancer Patients

1982 ◽  
Vol 68 (6) ◽  
pp. 477-480 ◽  
Author(s):  
Andrea Veronesi ◽  
Renato Talamini ◽  
Serenella Longhi ◽  
Diana Crivellari ◽  
Enzo Galligioni ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Carcinoembryonic Antigen ◽  
Cancer Patients ◽  
Relapse Rate ◽  
Patient Population ◽  
Prognostic Value ◽  
Radical Mastectomy ◽  
Breast Cancer Patients ◽  
Disease Free

Carcinoembryonic antigen (CEA) assays (2536) were performed in 380 disease-free breast cancer patients after radical mastectomy. In the 334 evaluable patients with 3 or more determinations, the overall relapse rate after a median follow-up of 29 months was 11 %. Of 203 patients with normal CEA values, 19 (9.3 %) relapsed. In the 50 patients with the highest CEA value greater than 20 ng/ml, the relapse rate was 26 %; in the 12 patients with gradually increasing CEA elevations it was 50 %. However, CEA was unable to predict recurrence in N- patients. Premastectomy N+ was significantly associated with greater than 20 ng/ml or gradually increasing CEA values, suggesting the lack of an independent prognostic value of CEA in our patient population.

scholarly journals CANCER PATIENTS

2006 ◽  
Vol 13 (03) ◽  
pp. 344-348
Author(s):  
MOHAMMAD JAWAID SABZWARI ◽  
Muhammad Riaz ◽  
MUKHTAR AHMAD ◽  
Muhammad Umair ◽  
MUHAMMAD TAHIR MAJEED
Keyword(s):  
Sialic Acid ◽  
Carcinoembryonic Antigen ◽  
Cancer Patients ◽  
Tumor Markers ◽  
Age Distribution ◽  
Laboratory Diagnosis ◽  
Cancer Management ◽  
Serum Sialic Acid ◽  
Diagnosis Of Cancer ◽  
Diagnostic Indicator

In the world cancer is one of the leading causes of death. Most cancerswhen detected early, can be potentially cured. Thus early laboratory diagnosis of cancer has great importance inmanagement. The tumor markers are one of the methods of cancer management in use today. Objectives: Tocompare serum sialic acid (SA) and carcinoembryonic antigen (CEA) as tumor markers in different cancer patients.Study Design: Prospective study Setting: Shaikh Zayed Medical Complex, Lahore. Material and Methods: Onehundred and fifty three (153) documented different cancer patients were studied to compare between serum sialic acidand carcinoembryonic antigen as a tumor marker along with fifty controls of matched sex and age distribution between30-85 years. The sialic acid was estimated by colorimetric procedure and carcinoembryonic antigen by EnzymeImmunoassay. Results: The results revealed that mean levels of sialic acid and CEA in cancer patients weresignificantly higher (p<0.05) as compared to controls, considering all malignancies together, or carcinoma,hematological malignancies and sarcoma alone. Statistical analysis showed sialic acid to be more sensitive (p<0.05)than CEA in detection of cancer. Conclusion: Sialic acid was seen to be a good diagnostic indicator as compared toCEA in most cancer patients.

scholarly journals Diagnostic usefulness of serum carcinoembryonic antigen determinations in breast cancer patients

2003 ◽  
Vol 3 (2) ◽  
pp. 30-34
Author(s):  
Zlata Mujagić ◽  
Hamza Mujagić
Keyword(s):  
Breast Cancer ◽  
Carcinoembryonic Antigen ◽  
Cancer Patients ◽  
Sensitivity And Specificity ◽  
Tumour Marker ◽  
Breast Cancer Patients ◽  
Female Patients ◽  
Healthy Women ◽  
Serum Carcinoembryonic Antigen ◽  
Circulating Levels

Background and purpose: Carcinoembryonic antigen (CEA) is used as a tumour marker in breast cancer (BC). In order to assess diagnostic value of CEA in BC we examined its serum levels and frequencies of its increase in breast cancer patients (BCP), and compared them to those in controls. We also determined CEA in patients with metastatic and non-metastatic BC, and calculated sensitivity and specificity of CEA in BC.Patients and methods: The main experimental group consisted of 47 female patients with histologically proved diagnosis of BC. There were two control groups: clinically healthy women, and female patients with other locations of cancer. Circulating levels of CEA were measured by means of immunoradiometric assay. Results were processed by means of t-test and two-way analysis of variance.Results: Circulating levels of CEA, before treatment in BCP, were significantly higher (p<0.0001) than in healthy women, and in patients with other cancers (p<0.007), while serum CEA in other cancer patients was significantly higher (p<0.01) than in healthy control. There was a difference between frequencies of CEA increase in BCP and healthy women, while such a difference did not exist between BCP and other cancer patients. The circulating levels of CEA in metastatic BCP were significantly higher (p<0.03) in comparison to non-metastatic patients. Sensitivity and specificity of CEA in BCP was 65.0%, and 57.1%, respectively.Conclusions: CEA does not have high tumour specificity for BC, since its circulating levels as well as frequencies of its increase may be elevated in patients with other types and locations of cancer, different from breast cancer. CEA can be detected in the serum of majority of patients with metastatic BC. CEA may be used as prognostic tumour marker in advanced BC.

scholarly journals The measurement of carcinoembryonic antigen in lung cancer patients and its clinical usefulness

Haigan ◽  
1979 ◽  
Vol 19 (3) ◽  
pp. 239-245
Author(s):  
Nobuyoshi Shimizu ◽  
Shin Matsumoto ◽  
Tetsuro Okazaki ◽  
Toyoji Wada ◽  
Kon Min Chen ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Carcinoembryonic Antigen ◽  
Cancer Patients ◽  
Clinical Usefulness ◽  
Lung Cancer Patients

scholarly journals Correlation Between Family Support and Emotional Regulation with The Resilience of Breast Cancer Patients in The City of Surabaya: A Literature Review

2020 ◽  
Vol 6 (1) ◽  
pp. 57
Author(s):  
Mauna Qurrotul Ain ◽  
Mira Triharini ◽  
Tiyas Kusumaningrum
Keyword(s):  
Breast Cancer ◽  
Family Support ◽  
Cancer Patients ◽  
Emotional Regulation ◽  
Breast Cancer Incidence ◽  
Psychological Impact ◽  
Emotional Reactions ◽  
Review Literature ◽  
Breast Cancer Patients ◽  
The Individual

Introduction: Breast cancer incidence has increased recently. Breast cancer patients usually feel inconvenience, psychological impact, and unstable emotions. The purpose of this study is to review the literature on the relationship between family support and emotional regulation with the resilience of breast cancer patients.Methods: The review literature search uses a database "Google Scholar, Sinta, Jurnal Ners dan Scopus with keywords "Family Support, Emotion Regulation, Resilience, Breast Cancer, Patient" in the last ten years 2009-2019.Results: 4,434 journals then identified for titles obtained as much as 2,142 and filtered according to abstract obtained 98 remaining journals, then review the complete full-text publication of a fully detailed 46 journal The final article that was in accordance with the inclusion criteria was 19 journals (articles).There is a significant relationship between family support and emotional regulation to the resilience of breast cancer patients.Conclusion: Family support can affect the health conditions felt by breast cancer patients; good emotional regulation is needed so that the patient can survive. On the articles that have been reviewed, Family support and hope given to people suffering from chronic diseases can be mediators of the emergence of resilient characters With good emotional regulation Individuals can control emotions by monitoring, evaluating and modifying emotional reactions, thus acquired adaptive emotions and organized behavior, then forming good self-acceptance and the individual feeling confident in him, able to live a life of positive, optimistic, and confident 

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