Granulomatous Synovitis: The Role of Atypical Mycobacteria

Mycobacterium fortuitum is a saprophytic, fast-growing, nontuberculous, and nonlepromatous mycobacterium that can cause infections in animals and humans. In dogs and cats, it is one of the most common agents of ulcerative dermatitides and panniculitides caused by atypical mycobacteria. In humans, it is frequently found in lipoid pneumonias or contaminated surgical sites. We report a cat with granulomatous pneumonia caused by M fortuitum resembling lipoid pneumonia in humans. The similarity between the histopathology of the lung and skin lesions caused by this organism in dogs and cats is emphasized. We discuss the role of lipids in the pathogenesis of mycobacterioses and suggest an association between atypical mycobacteria and lipid-rich environments. We conclude that M fortuitum should be included as a differential in cases of lipid-rich pneumonias that do not respond to common antibiotics.

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The role of infectious pathogens in exacerbation of chronic obstructive pulmonary disease in Dakahlia Governorate

Egyptian Journal of Bronchology ◽

10.1186/s43168-020-00039-6 ◽

2020 ◽

Vol 14 (1) ◽

Author(s):

Elsayed Ahmed Fahmy ◽

Heba Wagih Abdelwahab ◽

Heba Elsayed Eldegla ◽

Mohammed Khairy Fahmy Elbadrawy

Keyword(s):

Chronic Obstructive Pulmonary Disease ◽

Pulmonary Disease ◽

Negative Impact ◽

Fungal Growth ◽

Atypical Mycobacteria ◽

Chronic Obstructive ◽

Cross Sectional ◽

Obstructive Pulmonary Disease ◽

Copd Exacerbations

Abstract Background Exacerbations of chronic obstructive pulmonary disease (COPD) represent important events in the management of COPD because of its negative impact on health status and disease progression. The etiology of acute exacerbations of chronic obstructive pulmonary disease (COPDAE) is heterogeneous and still under discussion. So, this study was planned to investigate the role of infectious pathogens (fungi and atypical mycobacteria in addition to the well-known bacteria) in patients with COPD exacerbation in our locality. Results This observational cross-sectional study was conducted on 100 patients with acute exacerbation of COPD. Sputum specimens were collected for mycobacterial and fungal examination in addition to routine sputum bacteriology. All sputum samples were negative for typical and atypical mycobacteria whereas sputum samples of 18 patients (18%) were negative for fungi. Mixed fungal growth was found in 19 patients (19%). Candida was isolated from 67 patients (67%), Aspergillus was isolated from 27 patients (27%), Alternaria was isolated from 3 patients (3%), and other fungi were isolated from 4 patients (4%). As regards sputum bacteriology, sputum samples of 49 patients (49%) have bacterial growth. Streptococcus pneumoniae was isolated from 16 samples (16%) and represents the most frequent bacterial isolate in this study. Conclusion The present study indicates that typical and atypical mycobacteria have no role in COPD exacerbations in our locality. However, fungi and bacteria may have a role in COPD exacerbations.

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Mycobacterium marches back

The Journal of Laryngology & Otology ◽

10.1017/s0022215100129123 ◽

1995 ◽

Vol 109 (1) ◽

pp. 5-13 ◽

Cited By ~ 54

Author(s):

R. Gareth Williams ◽

Tony Douglas-Jones

Keyword(s):

Differential Diagnosis ◽

Hiv Infection ◽

Drug Treatment ◽

Head And Neck ◽

World Wide ◽

Cervical Lymphadenopathy ◽

Atypical Mycobacteria ◽

Recent Advances

AbstractThe resurgence of tuberculosis world-wide and its association with HIV infection means a greater likelihood of otolaryngologists encountering the disease in one form or another. In this review the features of primary and secondary tuberculosis in various head and neck sites are described, and recent advances in diagnosis are discussed. For the otolaryngologists other important aspects such as infections with atypical mycobacteria, the differential diagnosis of cervical lymphadenopathy in HIV-infected patients, recently recognized problems in drug treatment, and the role of surgery in head and neck tuberculosis are also discussed.

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Sepsis after Autologous Fat Grafting: Role of Atypical Mycobacteria

Plastic & Reconstructive Surgery ◽

10.1097/prs.0b013e31820e942a ◽

2011 ◽

Vol 127 (5) ◽

pp. 2120-2121 ◽

Cited By ~ 2

Author(s):

James R. Kanjoor

Keyword(s):

Fat Grafting ◽

Atypical Mycobacteria ◽

Autologous Fat Grafting ◽

Autologous Fat

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Paediatric neck abscesses: microbiology and management

The Journal of Laryngology & Otology ◽

10.1017/s0022215107009085 ◽

2007 ◽

Vol 122 (5) ◽

pp. 480-484 ◽

Cited By ~ 5

Author(s):

I K Rustom ◽

J A T Sandoe ◽

Z G G Makura

Keyword(s):

Mycobacterial Infection ◽

Neck Mass ◽

Atypical Mycobacteria ◽

Incision And Drainage ◽

Presenting Symptoms ◽

General Infirmary ◽

Intravenous Antibiotics ◽

Atypical Mycobacterial Infection ◽

The Mean

AbstractIntroduction:Paediatric neck abscesses remain common problems which are sometimes difficult to manage.Methods and materials:We conducted a retrospective study of 64 children who underwent incision and drainage of neck abscesses at Leeds General Infirmary from 1 February 2002 to 31 July 2006. The aim of this study was to identify the presenting symptoms in children, the appropriateness of prescribed antibiotics and the role of atypical mycobacteria in neck infections. The outcome measure was clinical resolution of the abscess.Results:The mean presenting age was 44.2 months (3.68 years). The commonest sign and symptom was neck mass (96.9 per cent). The mean period of hospitalisation was 3.7 (± standard deviation of 1.9) days. Staphylococcus aureus (48.4 per cent) was the commonest organism cultured. Atypical mycobacteria were found in only 4.7 per cent of the specimens. Flucloxacillin was the most common antibiotic used (57.8 per cent), often in combination with other antimicrobials. The abscess recurrence rate was 4.7 per cent. No fatalities occurred in this series of patients.Conclusion:Appropriately prescribed intravenous antibiotics and surgical drainage remain the central core of treatment. Atypical mycobacterial infection is an important differential diagnosis of a painless, cervico-facial mass. An algorithm for the management of paediatric neck abscesses is proposed.

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