scholarly journals Report of a Workshop on Respiratory Viral Infections: Epidemiology, Diagnosis, Treatment, and Prevention

1993 ◽  
Vol 16 (1) ◽  
pp. 151-164 ◽  
Author(s):  
K. McIntosh ◽  
P. Halonen ◽  
O. Ruuskanen
Author(s):  
E. Yu. Radtsig

Various methods and variants of nasal cavity irrigation are one of the most ancient in the treatment and prevention of diseases of the upper respiratory tract. When choosing a remedy for elimination and irrigation therapy, preference is given to preparations based on sea water, containing in its composition minerals and trace elements that cause additional therapeutic effect. A new direction in this type of therapy is the use of drugs containing fucoidans (obtained from brown algae extract). Their immunostimulatory and anti-inflammatory effect can improve the effectiveness of elimination and irrigation therapy in symptomatic treatment of ARVI / influenza and their complications (sinusitis, adenoiditis).


Pharmateca ◽  
2020 ◽  
Vol 1_2020 ◽  
pp. 80-91
Author(s):  
L.V. Osidak Osidak ◽  
O.I. Afanasyeva Afanasyeva ◽  
E.G. Golovacheva Golovacheva ◽  
V.V. Gonchar Gonchar ◽  
M.M. Pisareva Pisareva ◽  
...  

2017 ◽  
Vol 89 (8) ◽  
pp. 113-119 ◽  
Author(s):  
T V Sologub ◽  
V V Tsvetkov

The article provides the summarized data of clinical trials evaluating the efficacy and safety of kagocel used to prevent and treat influenza and acute respiratory viral infections of different etiologies. The results of numerous preclinical and clinical trials suggest that the kagocel substance is highly safe and that it is appropriate to use the drug for the treatment and prevention of influenza and acute respiratory viral infections of another etiology.


2020 ◽  
Vol 6 (1) ◽  
pp. 15-23
Author(s):  
V. V. Malinovskaya ◽  
I. G. Mosyagin ◽  
I. V. Korzhov

Conducting preventive medical and epidemiological measures for influenza and ARVI in closed military units, including on ships, vessels and auxiliary units of the Navy, is a factor of increasing the combat effectiveness of forces of the Russian Army. In the structure of total morbidity of military personnel, acute respiratory viral infections account for 35–50%, however, during the young military reinforcement, the incidence of these infections in combination with community-acquired pneumonia can reach 70–80%. The risk of exceeding the epidemiological threshold for respiratory tract infections, the etiological basis of which is viral aggression, is especially important in newly formed military contingents, for units participating in local military conflicts and peacekeeping operations, as well as with a new recruitment of cadets at training centers. The use of non-specific antiviral drugs based on exogenous recombinant interferon -2b is one of the conditions for adequate prevention of influenza and ARVI in closed military units. The paper presents the results from the analysis of publications on the effectiveness and Viferon® safety in the treatment of influenza and ARVI. Viferon is a preparation of recombinant human interferon -2b with a complex of antioxidants in various dosage forms, used in the treatment and prevention of acute respiratory viral infections and influenza. Use of Viferon in various dosage forms is a reliable method of prevention and treatment of influenza and other acute respiratory viral infections in military forces, including on ships, vessels and auxiliary units of the Navy, at risk of emergency epidemiological situations due to ARVI and influenza, in conditions of limited contingent.


2016 ◽  
Vol 1 (1) ◽  
pp. 50-53 ◽  
Author(s):  
Y. L. Mizernitskiy

The article presents data on the place of the modern endogenous interferon inducers in the treatment and prevention of influenza and ARVI in children and the mechanisms of action. The focus is on the domestic antiviral innovation Kagocel which demonstrated high clinical efficacy and safety in a number of multi-center, blind, placebo-controlled studies of the treatment and prevention of ARVI/flu in children over 2 years old.


2021 ◽  
pp. 46-59
Author(s):  
O.A. Gizinger

The article describes the types and biological characteristics of interferons, which are an integral part of the antiviral defense of the body. The possibilities of using interferons, interferon inducers in the complex treatment of acute respiratory viral infections are shown. The validity and possible risks of using interferon preparations for the treatment and prevention of acute respiratory viral infections are analyzed, taking into account information about their mechanisms of action.


2020 ◽  
Vol 19 (2) ◽  
pp. 42-46
Author(s):  
O. V. Shamsheva ◽  
E. V. Novosad ◽  
I. V. Polesko ◽  
V. F. Uchaykin ◽  
V. V. Malinovskaya ◽  
...  

The review article presents the results of numerous studies on the effectiveness and safety of the newly developed forms of the human recombinant interferon alpha- 2b drug, ointment and gel, intended for the treatment and prevention of acute respiratory viral infections and influenza in children. Еxternal forms of the drug retain immunomodulatory, antiviral and antiproliferative effects. The dosage form of the preparation of interferon alpha-2b VIFERON® in the form of a gel or ointment allows to achieve a prolonged action due to good absorption, especially the gel, which increases its effectiveness, and also has a moisturizing effect and rarely causes allergies. All of the above properties justify the inclusion of the drug interferon alpha-2b VIFERON® in the form of a gel or ointment in the complex treatment of influenza and acute respiratory viral infections in children.


2021 ◽  
Vol 9 (1) ◽  
pp. 17-23
Author(s):  
S.О. Kramarov ◽  
V.V. Yevtushenko

Interferons are cytokines that are produced by immunocompetent cells in response to the invasion of an infectious factor. The most important biological effect of interferons used in clinical practice is their ability to nonspecifically inhibit viral replication. This article summarizes the functions of interferons in the implementation of the functions of innate and acquired immunity. The possibilities of using intranasal interferons for the treatment and prevention of the most common viral diseases in children, in particular acute respiratory viral infections, SARS and SARS-CoV-2, are considered.


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