Effect of intermittent high altitude hypoxia on the synthesis of collagenous and non-collagenous proteins of the right and left ventricular myocardium

1978 ◽  
Vol 12 (5) ◽  
pp. 303-308 ◽  
Author(s):  
B. OSTADAL ◽  
E. MIREJOVSKA ◽  
J. HURYCH ◽  
V. PELOUCH ◽  
J. PROCHAZKA
Keyword(s):  
High Altitude ◽  
Ventricular Myocardium ◽  
Left Ventricular ◽  
Left Ventricular Myocardium ◽  
Altitude Hypoxia ◽  
High Altitude Hypoxia ◽  
The Right

scholarly journals Possibly Late-Onset Arrhythmogenic Right Ventricular Cardiomyopathy: Unique Triglyceride Deposition by Analysis of Lipid Contents

2019 ◽  
Vol 12 ◽  
pp. 117954761982871
Author(s):  
Kentaro Yamamoto ◽  
Xin Guo ◽  
Ken-ichi Mizutani ◽  
Nozomu Kurose ◽  
Motona Kumagai ◽  
...  
Keyword(s):  
Right Ventricular ◽  
Late Onset ◽  
Arrhythmogenic Right Ventricular Cardiomyopathy ◽  
Ventricular Myocardium ◽  
Cholesterol Content ◽  
Left Ventricular ◽  
Left Ventricular Myocardium ◽  
Ventricular Cardiomyopathy ◽  
Lipid Contents ◽  
The Right

We presented an unusual arrhythmogenic right ventricular cardiomyopathy (ARVC) case of a late-60s elderly man’s death, due to severe pericardial/pleural effusion and ascites, and arrhythmic events, with unique pathological features. The hypertrophic heart grossly displayed yellowish to yellow-whitish predominantly in the variably thinned wall of the dilated right ventricle. Microscopic findings showed diffuse fatty/fibrofatty replacement in not only the right but left ventricular myocardium, together with an outer lymphoplasmacytic infiltrate. According to the lipid contents analysis, the triglyceride content, but not the cholesterol content, in our patient’s right and left ventricular cardiac muscle was much higher than that in the control subject. We propose that this unique triglyceride deposition in our possibly late-onset ARVC case might be one of new clues to understand its enigmatic cause. Further prospective studies are needed to validate the presence and significance of a greater volume of triglyceride deposit, after collecting and investigating a larger number of early and late-onset ARVC cases examined.

Noncompaction of the myocardium associated with Roifman syndrome

2001 ◽  
Vol 11 (2) ◽  
pp. 240-243 ◽  
Author(s):  
Karen Mandel ◽  
Eyal Grunebaum ◽  
Lee Benson
Keyword(s):  
Interventricular Septum ◽  
Retinal Dystrophy ◽  
Ventricular Myocardium ◽  
Left Ventricular ◽  
Antibody Deficiency ◽  
Left Ventricular Myocardium ◽  
Facial Dysmorphism ◽  
Ventricular Wall ◽  
Immune Deficiencies ◽  
The Right

Noncompaction of the ventricular myocardium, sometimes referred to as “spongy myocardium”, appears as excessive and prominent trabeculations and deep intratrabecular recesses within the ventricular wall, usually involving the left ventricle, although the right ventricle and interventricular septum can also be affected. It may occur with or without additional heart malformations. Roifman syndrome is a constellation of antibody deficiency, spondyloepiphyseal dysplasia, facial dysmorphism, growth retardation, and retinal dystrophy. We report a patient with Roifman syndrome who presented with noncompaction of the left ventricular myocardium. Our findings expand the spectrum of diseases associated with noncompaction. The recognition of noncompaction among patients with Roifman syndrome is important, as the immune deficiencies may be subtle and undiagnosed until adulthood. Thus, some patients may first present with cardiac failure.

Absence of the left ventricular myocardium in a newborn

1996 ◽  
Vol 6 (4) ◽  
pp. 344-347 ◽  
Author(s):  
Angelika Lindinger ◽  
Yvonne Masur ◽  
Hans-Gerhard Limbach
Keyword(s):  
Aortic Valve ◽  
Left Ventricle ◽  
Ventricular Myocardium ◽  
Arrhythmogenic Right Ventricular Dysplasia ◽  
Left Ventricular ◽  
Adolescent And Young Adult ◽  
Left Ventricular Myocardium ◽  
Fatty Replacement ◽  
Myocardial Fibers ◽  
The Right

SummaryAbsence of myocardial fibers in the right ventricle is the essence of so-called Uhl's anomaly, which should be distinguished from the fatty replacement producing arrhythmogenic right ventricular dysplasia of the adolescent and young adult. In this report, we describe a newborn with nearly complete absence of the myocardium of the left ventricle. The infant died on the seventh day because of myocardial incompetence of the left ventricle, which was unable to open the aortic valve.

scholarly journals Effects of high altitude hypoxia on left ventricular systolic time intervals in man.

Heart ◽  
1975 ◽  
Vol 37 (3) ◽  
pp. 272-276 ◽  
Author(s):  
V Balasubramanian ◽  
V S Kaushik ◽  
S C Manchanda ◽  
S B Roy
Keyword(s):  
High Altitude ◽  
Systolic Time Intervals ◽  
Left Ventricular ◽  
Time Intervals ◽  
Altitude Hypoxia ◽  
High Altitude Hypoxia ◽  
Systolic Time

scholarly journals Quantified growth of the human embryonic heart

Biology Open ◽  
2021 ◽  
Vol 10 (2) ◽  
pp. bio057059 ◽  
Author(s):  
Jaeike W. Faber ◽  
Jaco Hagoort ◽  
Antoon F. M. Moorman ◽  
Vincent M. Christoffels ◽  
Bjarke Jensen
Keyword(s):  
Heart Development ◽  
Three Dimensional ◽  
Ventricular Myocardium ◽  
Left Ventricular ◽  
Embryonic Heart ◽  
Growth Patterns ◽  
Right Atrial ◽  
Left Ventricular Myocardium ◽  
Atrioventricular Canal ◽  
The Right

ABSTRACTThe size and growth patterns of the components of the human embryonic heart have remained largely undefined. To provide these data, three-dimensional heart models were generated from immunohistochemically stained sections of ten human embryonic hearts ranging from Carnegie stage 10 to 23. Fifty-eight key structures were annotated and volumetrically assessed. Sizes of the septal foramina and atrioventricular canal opening were also measured. The heart grows exponentially throughout embryonic development. There was consistently less left than right atrial myocardium, and less right than left ventricular myocardium. We observed a later onset of trabeculation in the left atrium compared to the right. Morphometry showed that the rightward expansion of the atrioventricular canal starts in week 5. The septal foramina are less than 0.1 mm2 and are, therefore, much smaller than postnatal septal defects. This chronological, graphical atlas of the growth patterns of cardiac components in the human embryo provides quantified references for normal heart development. Thereby, this atlas may support early detection of cardiac malformations in the foetus.This article has an associated First Person interview with the first author of the paper.

Sign in / Sign up

Export Citation Format

Share Document