scholarly journals P655. Biosimilar infliximab CT-P13 treatment in patients with inflammatory bowel diseases: a 1-year, single-centre retrospective study

2016 ◽  
Vol 10 (suppl 1) ◽  
pp. S433.2-S433
2016 ◽  
Vol 70 (1) ◽  
pp. 27-36 ◽  
Author(s):  
Tibor Hlavatý ◽  
Anna Krajčovičová ◽  
Igor Šturdík ◽  
Juraj Letkovský ◽  
Tomáš Koller ◽  
...  

2011 ◽  
Vol 140 (5) ◽  
pp. S-436-S-437
Author(s):  
Sandrine Barge ◽  
Severine Feuillet ◽  
Jean-Marc Gornet ◽  
Jacques Cosnes ◽  
Jean-Frederic Colombel ◽  
...  

Rheumatology ◽  
2021 ◽  
Vol 60 (Supplement_5) ◽  
Author(s):  
N Nassiri ◽  
M Rkain ◽  
A El Ouali ◽  
A Ghannam ◽  
A Babakhouya ◽  
...  

Abstract Background Joint manifestations during chronic inflammatory bowel diseases (IBD) represent the most frequent extra digestive manifestations, dominated by spondylarthropathy, isolated sacroillitis and peripheral rheumatism. We conducted a retrospective study of 9 cases of IBD collected in the pediatric services of the CHU MOHAMMED VI of Oujda over a 4 year period from July 2017 to March 2021.The objective of our study is to describe the joint manifestations in inflammatory bowel diseases in children. Materials and methods This is a retrospective study of 9 cases of IBD collected in the pediatric services of the CHU MOHAMMED VI of Oujda over a 4-year period from June 2017 to March 2021. All these parameters were collected on operating sheets and reported on ExcelThe data were collected from the files registered in a pediatric hospitalization register Results Our study includes 9 patients with male predominance in 60% of cases, the prevalence of joint manifestations was 45% of which 3/4 of cases are in Crohn's disease and 1/4 of cases in UC.Axial joint involvement was 25% in Crohn's disease while joint involvement was peripheral in 75% of which 2/3 in Crohn's and 1/3 in UC.Peripheral involvement affects the large joints in all patients with a bilateral character. With a biological inflammatory syndrome in which the CRP was >50 mg/l and the VS more than 30All patients received corticotherapy and analgesics in 25% of cases. The evolution was marked by a good clinical and biological improvement with an average delay of 10 days. Discussion Ulcerative colitis (UC) and Crohn's disease (CD) are chronic cryptogenetic inflammatory bowel diseases (IBD). In addition to intestinal involvement, these IBDs are associated in 20% to30% of cases with extra digestive manifestations, with joint manifestations being the most frequent. There are essentially two types: Peripheral attacks which are the most frequent (8–20% of patients) especially during Crohn's disease; All joints can be affected, but most often asymmetric oligoarthritisAxial involvement includes sacroiliitis (SI) and ankylosing spondylitis (SpA) SI is more prevalent than SpA in both UC and CD Treatment of joint manifestations involves rest and exercise% tocontrol spinal stiffening in axial involvement; and analgesics Close collaboration between gastro-pediatricians and pediatric rheumatologists is the key to optimal management of the extra-digestive manifestations of IBD. Conclusion Joint involvement plays an important role in the extra digestive manifestations of IBD. It should be systematically screened in IBD patients, especially if they present a biological inflammatory syndrome, thus enabling early diagnosis and better management.


2019 ◽  
Vol 13 (Supplement_1) ◽  
pp. S472-S473
Author(s):  
F S Macaluso ◽  
A Croce ◽  
R Orlando ◽  
M Ventimiglia ◽  
C Sapienza ◽  
...  

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