scholarly journals P905One year follow-up of box isolation in persistent atrial fibrillation ablation: role of insertable cardiac monitoring

EP Europace ◽  
2017 ◽  
Vol 19 (suppl_3) ◽  
pp. iii177-iii178
Author(s):  
G. Sirico ◽  
M. Morosato ◽  
S. Panigada ◽  
L. Ottaviano ◽  
V. De Sanctis ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Persistent Atrial Fibrillation ◽  
Atrial Fibrillation Ablation ◽  
Cardiac Monitoring

scholarly journals P1436Long term follow-up of box isolation in persistent atrial fibrillation ablation

EP Europace ◽  
2017 ◽  
Vol 19 (suppl_3) ◽  
pp. iii288-iii288
Author(s):  
G. Sirico ◽  
M. Morosato ◽  
S. Panigada ◽  
L. Ottaviano ◽  
V. De Sanctis ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Persistent Atrial Fibrillation ◽  
Atrial Fibrillation Ablation

scholarly journals Long-standing Persistent Atrial Fibrillation Ablation: the Role of the Inter- and Intra-atrial Bundles

2020 ◽  
Vol 33 (2) ◽  
pp. 73-81
Author(s):  
Russell Mitchell ◽  
Cesar Augusto Bonilla Isaza
Keyword(s):  
Atrial Fibrillation ◽  
Catheter Ablation ◽  
Clinical Outcomes ◽  
Pulmonary Veins ◽  
Persistent Atrial Fibrillation ◽  
Conduction System ◽  
Atrial Fibrillation Ablation ◽  
Anatomical Location

Catheter ablation has become the mainstream treatment of atrial fibrillation, but still remains a challenge in those patient with persistent and long standing persistent atrial fibrillation. In addition of isolation of the pulmonary veins, any other areas that can trigger or perpetuate atrial fibrillation need to be isolated. Current technologies may allow to effectively deliver permanently lasting lesions, and therefore improve clinical outcomes after ablation. The specialized conduction system including the Bachmann and septopulmonary bundles, are important substrate targets for the management of atrial fibrillation. The anatomical location of these fibers, and the corresponding approach for ablation are described in this case.

scholarly journals Role of Rotors in the Ablative Therapy of Persistent Atrial Fibrillation

2015 ◽  
Vol 4 (1) ◽  
pp. 47 ◽  
Author(s):  
Amir A Schricker ◽  
Junaid Zaman ◽  
Sanjiv M Narayan ◽  
◽  
◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Persistent Atrial Fibrillation ◽  
Contact Mapping ◽  
Long Term Follow Up ◽  
Fibrillatory Conduction ◽  
Procedural Success ◽  
Maintain Sinus Rhythm

Atrial fibrillation (AF) ablation is increasingly used to maintain sinus rhythm yet its results are sub-optimal, especially in patients with persistent AF or prior unsuccessful procedures. Attempts at improvement have often targeted substrates that sustain AF after it is triggered, yet those mechanisms are debated. Many studies now challenge the concept that AF is driven by self-sustaining disordered wavelets, showing instead that localised drivers (rotors) may drive disorder via a process known as fibrillatory conduction. Novel mapping using wide-area recordings, physiological filtering and phase analysis demonstrates rotors in human AF. Contact mapping with focal impulse and rotor modulation (FIRM) shows that localised ablation at sources can improve procedural success in many populations on long-term follow up and some newer approaches to rotor mapping are qualitatively similar. This review critically evaluates the data on rotor mapping and ablation, which advances our conceptual understanding of AF and holds the promise of substantially improving ablative outcomes in patients with persistent AF.

scholarly journals Long-term follow-up of persistent atrial fibrillation ablation using termination as a procedural endpoint

2009 ◽  
Vol 30 (9) ◽  
pp. 1105-1112 ◽  
Author(s):  
M. D. O'Neill ◽  
M. Wright ◽  
S. Knecht ◽  
P. Jais ◽  
M. Hocini ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Persistent Atrial Fibrillation ◽  
Atrial Fibrillation Ablation ◽  
Long Term Follow Up

Biomarkers Determining Prognosis of Atrial Fibrillation Ablation

2019 ◽  
Vol 26 (5) ◽  
pp. 925-937 ◽  
Author(s):  
Dimitris Tsiachris ◽  
George Giannopoulos ◽  
Spyridon Deftereos ◽  
Charis Kossyvakis ◽  
Constantinos Tsioufis ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Catheter Ablation ◽  
Inflammatory Markers ◽  
Persistent Atrial Fibrillation ◽  
Atrial Fibrillation Ablation ◽  
Oxidative Stress Biomarkers ◽  
Specific Patient ◽  
Term Administration ◽  
The Impact

Catheter ablation for rhythm control is recommended in specific patient populations with paroxysmal, persistent, or long-standing persistent atrial fibrillation. Pulmonary vein isolation is the cornerstone of the ablative therapy for atrial fibrillation. However, relapse is still common since the single procedure efficacy of atrial fibrillation ablation was estimated to be 60-80% in paroxysmal and 50-70% in persistent atrial fibrillation. It is important to identify predictors of successful atrial fibrillation patients ablation. In the present review, we will assess the role of available biomarkers to predict responders of an initial atrial fibrillation catheter ablation. Emphasis has been given on the role of myocardial injury biomarkers, natriuretic peptides and traditional inflammatory markers. Novel inflammatory markers, oxidative stress biomarkers and microRNAs have also been examined as predictors of a successful atrial fibrillation procedure. Notably, the impact of procedural and short-term administration of steroids, as well as the role of colchicine on preventing atrial fibrillation recurrence after ablation is thoroughly presented.

Role of Pulmonary Veins Isolation in Persistent Atrial Fibrillation Ablation:

2009 ◽  
Vol 32 ◽  
pp. S116-S119 ◽  
Author(s):  
GIUSEPPE STABILE ◽  
EMANUELE BERTAGLIA ◽  
PIETRO TURCO ◽  
FRANCO ZOPPO ◽  
ASSUNTA IULIANO ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Pulmonary Veins ◽  
Persistent Atrial Fibrillation ◽  
Atrial Fibrillation Ablation

The Role of Atrial Fibrosis Detected by Delayed - Enhancement MRI in Atrial Fibrillation Ablation

2020 ◽  
Vol 16 (2) ◽  
pp. 135-144 ◽  
Author(s):  
Zsuzsanna Kis ◽  
Astrid Amanda Hendriks ◽  
Taulant Muka ◽  
Wichor M. Bramer ◽  
Istvan Kovacs ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Imaging Modality ◽  
Final Analysis ◽  
Atrial Fibrosis ◽  
Atrial Wall ◽  
Af Ablation ◽  
Left Atrial Wall ◽  
Cmr Imaging

Introduction: Atrial Fibrillation (AF) is associated with remodeling of the atrial tissue, which leads to fibrosis that can contribute to the initiation and maintenance of AF. Delayed- Enhanced Cardiac Magnetic Resonance (DE-CMR) imaging for atrial wall fibrosis detection was used in several studies to guide AF ablation. The aim of present study was to systematically review the literature on the role of atrial fibrosis detected by DE-CMR imaging on AF ablation outcome. Methods: Eight bibliographic electronic databases were searched to identify all published relevant studies until 21st of March, 2016. Search of the scientific literature was performed for studies describing DE-CMR imaging on atrial fibrosis in AF patients underwent Pulmonary Vein Isolation (PVI). Results: Of the 763 citations reviewed for eligibility, 5 articles (enrolling a total of 1040 patients) were included into the final analysis. The overall recurrence of AF ranged from 24.4 - 40.9% with median follow-up of 324 to 540 days after PVI. With less than 5-10% fibrosis in the atrial wall there was a maximum of 10% recurrence of AF after ablation. With more than 35% fibrosis in the atrial wall there was 86% recurrence of AF after ablation. Conclusion: Our analysis suggests that more extensive left atrial wall fibrosis prior ablation predicts the higher arrhythmia recurrence rate after PVI. The DE-CMR imaging modality seems to be a useful method for identifying the ideal candidate for catheter ablation. Our findings encourage wider usage of DE-CMR in distinct AF patients in a pre-ablation setting.

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