Clinical Cases: Masses, tumors and source of embolism82A case of right atrial diverticulum initially diagnosed in 58 years old female patient83Unusual cardiac mass84A very rare cardiac mass in the right atrium85A rare cause of syncope: intravenous leiomyomatosis with cardiac extension86Left ventricular myxoma- a rare finding87Mediastinal masses and a left atrial tumor: are they related? -the role of multimodal imaging in the diagnosis and the management of the patient

Sinusoidal volume changes (+/- 1 ml) were applied at 1 Hz to the right or left atrium of 25 anesthetized cats. Changes in firing rates of single vagal fibers and in plasma ACTH and cortisol were observed in response to start and stop of atrial pulsation. Decreased activity of right atrial and/or septal B-receptors was associated with increased ACTH. Changes in left atrial B-receptor activity were associated with a change in ACTH only if right atrial/septal receptors or baroreceptors also changed their activity in the same direction. The activity of atrial A-receptors did not change in response to atrial pulsation. A quantitative analysis suggested strongly that right atrial and/or septal B-receptors dominate in the response of ACTH to hemodynamic stimuli. Arterial receptors appear less effective, and left atrial B-receptors appear least effective in the hemodynamic control of ACTH.

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Cobra head deformity of atrial septal occluder: blessing in disguise

Cardiology in the Young ◽

10.1017/s1047951120004084 ◽

2020 ◽

pp. 1-2

Author(s):

Uma Devi Karuru ◽

Saurabh Kumar Gupta

Keyword(s):

Atrial Septal Defect ◽

Left Atrial ◽

Septal Defect ◽

Atrial Septum ◽

Right Atrial ◽

Septal Occluder Device ◽

Occluder Device ◽

The Right

Abstract It is not uncommon to have prolapse of the atrial septal occluder device despite accurate measurement of atrial septal defect and an appropriately chosen device. This is particularly a problem in cases with large atrial septal defect with absent aortic rim. Various techniques have been described for successful implantation of atrial septal occluder in such a scenario. The essence of all these techniques is to prevent prolapse of the left atrial disc through the defect while the right atrial disc is being deployed. In this brief report, we illustrate the use of cobra head deformity of the device to successfully deploy the device across the atrial septum.

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Control of atrial natriuretic factor by right and left atrial distension in pregnant sheep

AJP Regulatory Integrative and Comparative Physiology ◽

10.1152/ajpregu.1995.268.6.r1411 ◽

1995 ◽

Vol 268 (6) ◽

pp. R1411-R1417

Author(s):

D. Javeshghani ◽

S. Mukaddam-Daher ◽

L. Fan ◽

Z. Guan ◽

J. Gutkowska ◽

...

Keyword(s):

Atrial Natriuretic Factor ◽

Left Atrial ◽

Atrial Pressure ◽

Right Atrial ◽

Natriuretic Factor ◽

Pregnant Sheep ◽

Vascular Catheters ◽

The Right ◽

Left Atrial Distension ◽

Atrial Natriuretic

Previous studies of the atrial stretch-atrial natriuretic factor (ANF) relationship during pregnancy have employed volume expansion and measured only right atrial pressure (RAP). Consequently, we studied nonpregnant (n = 7) and 115- to 125-day pregnant (n = 7) sheep and assessed the ANF response to changes of RAP and left atrial pressure (LAP) induced by graded balloon inflation. Ewes prepared with vascular catheters and atrial balloons were studied after recovery from preparatory surgical procedures. The basal levels of mean arterial pressure (MAP, 83 +/- 3 mmHg), RAP (2.1 +/- 0.7 mmHg), LAP (4.7 +/- 0.9 mmHg), and heart rate (HR, 102 +/- 6 beats/min) were similar in nonpregnant and pregnant sheep. Pregnancy also resulted in elevation of ANF concentration from 25 +/- 6 to 57 +/- 4 fmol/ml. With right atrial distension, the RAP-ANF relationships were similar in both nonpregnant and pregnant sheep, with a 10-mmHg increase in RAP increasing ANF by an average of 95 +/- 9 fmol/ml. In nonpregnant sheep, the LAP-ANF relationship was more responsive than RAP-ANF because a 10-mmHg increase in LAP resulted in a 193 +/- 10 fmol/ml increase in ANF. Moreover, during pregnancy, the LAP-ANF relationship was significantly more sensitive because a 10-mmHg increase in LAP resulted in a 433 +/- 15 fmol/ml elevation of ANF. These data demonstrate that plasma ANF levels are more responsive to distension of the left atria than to the right. More importantly, the ANF response to left, but not right, atrial distension is enhanced by pregnancy.

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Intimal Sarcoma: An Extremely Rare Case of a Left Atrial Tumor with Partial Obstruction of the Mitral Orifice

CASE ◽

10.1016/j.case.2020.12.009 ◽

2021 ◽

Author(s):

Tamami Nakagawa-Kamiya ◽

Mika Mori ◽

Miho Ohira ◽

Kenji Iino ◽

Masa-aki Kawashiri ◽

...

Keyword(s):

Left Atrial ◽

Rare Case ◽

Partial Obstruction ◽

Intimal Sarcoma ◽

Mitral Orifice ◽

Left Atrial Tumor ◽

Atrial Tumor

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Role of right heart receptors in the control of renin, vasopressin, and cortisol secretion in dogs

AJP Regulatory Integrative and Comparative Physiology ◽

10.1152/ajpregu.1992.263.5.r1071 ◽

1992 ◽

Vol 263 (5) ◽

pp. R1071-R1077 ◽

Cited By ~ 3

Author(s):

D. H. Carr ◽

D. B. Jennings ◽

T. N. Thrasher ◽

L. C. Keil ◽

D. J. Ramsay

Keyword(s):

Inferior Vena ◽

Vena Cava ◽

Plasma Renin ◽

Atrial Pressure ◽

Right Atrial ◽

Right Heart ◽

Hormonal Responses ◽

The Right ◽

Maximal Reduction

We have reported that increased left heart pressure inhibits increases in plasma renin activity (PRA), arginine vasopressin (AVP), and cortisol during arterial hypotension. The goal of this study was to determine whether increases in right heart pressure also inhibited hormonal responses to hypotension. Seven dogs were chronically instrumented with inflatable cuffs around the ascending aorta (AA), the pulmonary artery (PA), and the thoracic inferior vena cava (IVC), as well as with catheters in both atria, the abdominal aorta, and vena cava. The IVC, the PA, and the AA cuffs were inflated on different days to cause step reductions in mean arterial pressure (MAP) of 5, 10, 20, and 30% below control MAP. Graded constriction of the AA caused large increases in left atrial pressure and plasma atrial natriuretic peptide (ANP), but had no effect on plasma AVP or cortisol and caused only a small increase in PRA at the maximal reduction of MAP. Constriction of the IVC reduced both atrial pressures and plasma ANP, but stimulated increases in PRA, AVP, and cortisol. Constriction of the PA increased right atrial pressure and plasma ANP and caused increases in plasma AVP and cortisol that were similar to responses during IVC constriction, but the PRA response was only half (P < 0.05). These results indicate that increasing pressure on the right side of the heart can attenuate the PRA response to hypotension, and suggest that the inhibition is mediated by the rise in plasma ANP.

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Cross-sectional echocardiographic diagnosis of large left atrial tumor and extracardiac tumor compressing the left atrium

The American Journal of Cardiology ◽

10.1016/0002-9149(78)90107-8 ◽

1978 ◽

Vol 42 (5) ◽

pp. 853-857 ◽

Cited By ~ 30

Author(s):

Junichi Yoshikawa ◽

Irfan Sabah ◽

Koji Yanagihara ◽

Takane Owaki ◽

Hiroshi Kato ◽

...

Keyword(s):

Left Atrium ◽

Left Atrial ◽

Cross Sectional ◽

Left Atrial Tumor ◽

Atrial Tumor

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Left Atrial Tumor Simulating Mitral Stenosis Combined With Rheumatic Mitral Insufficiency — Removal of the Tumor and Heart Valve Replacement With the St. Jude Medical Prosthesis

Cardiovascular Surgery 1980 ◽

10.1007/978-3-642-68172-1_151 ◽

1981 ◽

pp. 757-757

Author(s):

F. W. Hehrlein ◽

J. Mulch ◽

P. Walter ◽

H. Scheld

Keyword(s):

Valve Replacement ◽

Heart Valve ◽

Mitral Stenosis ◽

Left Atrial ◽

Heart Valve Replacement ◽

Mitral Insufficiency ◽

Jude Medical ◽

Left Atrial Tumor ◽

Atrial Tumor

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Atrial Fibrillation Progression Is Associated with Cell Senescence Burden as Determined by p53 and p16 Expression

Journal of Clinical Medicine ◽

10.3390/jcm9010036 ◽

2019 ◽

Vol 9 (1) ◽

pp. 36

Author(s):

Laurence Jesel ◽

Malak Abbas ◽

Sin-Hee Park ◽

Kensuke Matsushita ◽

Michel Kindo ◽

...

Keyword(s):

Atrial Fibrillation ◽

Heart Surgery ◽

Open Heart Surgery ◽

Right Atrial ◽

Atrial Remodeling ◽

Inflammatory Proteins ◽

Underlying Mechanisms ◽

The Right ◽

New Evidence

Background: Whilst the link between aging and thrombogenicity in atrial fibrillation (AF) is well established, the cellular underlying mechanisms are unknown. In AF, the role of senescence in tissue remodeling and prothrombotic state remains unclear. Aims: We investigated the link between AF and senescence by comparing the expression of senescence markers (p53 and p16), with prothrombotic and inflammatory proteins in right atrial appendages from patients in AF and sinus rhythm (SR). Methods: The right atrial appendages of 147 patients undergoing open-heart surgery were harvested. Twenty-one non-valvular AF patients, including paroxysmal (PAF) or permanent AF (PmAF), were matched with 21 SR patients according to CHA2DS2-VASc score and treatment. Protein expression was assessed by tissue lysates Western blot analysis. Results: The expression of p53, p16, and tissue factor (TF) was significantly increased in AF compared to SR (0.91 ± 0.31 vs. 0.58 ± 0.31, p = 0.001; 0.76 ± 0.32 vs. 0.35 ± 0.18, p = 0.0001; 0.88 ± 0.32 vs. 0.68 ± 0.29, p = 0.045, respectively). Expression of endothelial NO synthase (eNOS) was lower in AF (0.25 ± 0.15 vs. 0.35 ± 0.12, p = 0.023). There was a stepwise increase of p53, p16, TF, matrix metalloproteinase-9, and an eNOS progressive decrease between SR, PAF, and PmAF. AF was the only predictive factor of p53 and p16 elevation in multivariate analysis. Conclusions: The study brought new evidence indicating that AF progression is strongly related to human atrial senescence burden and points at a link between senescence, thrombogenicity, endothelial dysfunction and atrial remodeling.

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