scholarly journals Bilateral pulmonary artery stenosis with pulmonary hypertension due to Takayasu’s arteritis, examined using quantitative flow ratio during revascularisation

2021 ◽  
Author(s):  
Qi-Xian Zeng ◽  
Tao Yang ◽  
Qun-Ying Xi ◽  
Zhi-Hui Zhao
Keyword(s):  
Pulmonary Artery ◽  
Takayasu’S Arteritis ◽  
Artery Stenosis ◽  
Pulmonary Artery Stenosis ◽  
Takayasu's Arteritis ◽  
Effect Evaluation ◽  
Vascular Assessment ◽  
Pulmonary Arterial ◽  
Quantitative Flow Ratio ◽  
Therapeutic Effect Evaluation

Abstract Therapeutic effect evaluation is based on morphology performed by angiography conventionally. QFR is a new angiography-based tool for vascular assessment of functional severity. We report the first QFR examination in the field of Takayasu's arteritis patient with pulmonary artery stenosis and pulmonary arterial hypertension. It seems simple and practicable during off-line pulmonary artery intervention assessment.

scholarly journals Takayasu’s arteritis with bilateral pulmonary artery stenosis

1987 ◽  
Vol 94 (2) ◽  
pp. 246-250 ◽  
Author(s):  
S. Chauvaud ◽  
L. Mace ◽  
P. Brunewald ◽  
J.L. Tricot ◽  
J.P. Camilleri ◽  
...  
Keyword(s):  
Pulmonary Artery ◽  
Takayasu’S Arteritis ◽  
Artery Stenosis ◽  
Pulmonary Artery Stenosis ◽  
Takayasu's Arteritis

scholarly journals Pulmonary artery stenting in a patient with Takayasu’s arteritis using a novel balloon-expandable covered stent

2019 ◽  
Vol 7 ◽  
pp. 2050313X1984195 ◽  
Author(s):  
Barry S Weinstock ◽  
Yitzhak Daniel Haim
Keyword(s):  
Pulmonary Artery ◽  
Takayasu’S Arteritis ◽  
Main Pulmonary Artery ◽  
Covered Stent ◽  
Artery Stenosis ◽  
Pulmonary Artery Stenosis ◽  
Interventional Treatment ◽  
Takayasu's Arteritis ◽  
Increased Risk ◽  
Pulmonary Artery Rupture

Patients with Takayasu’s arteritis have pulmonary artery involvement more commonly than previously appreciated. The majority of these lesions are in segmental or sub-segmental arteries, but there are some patients who have severe stenosis of the main pulmonary arteries. Interventional treatment of these patients is technically feasible, but there are only limited case reports describing such intervention. Balloon angioplasty and stenting in these lesions often require high pressure inflations to achieve adequate results and thus has increased risk due to the possibility of pulmonary artery rupture. The recently approved Viabahn BX balloon-expandable covered stent may be an optimal device for main pulmonary artery stenosis as it is relatively low profile, can be over-expanded to large vessel diameter without compromise or disruption of the polytetrafluoroethylene covering and virtually eliminates the risk of catastrophic pulmonary artery rupture. We report here the first known use of this novel stent for treatment of severe pulmonary artery stenosis.

scholarly journals Identification and characterization of a novel ELN mutation in congenital heart disease with pulmonary artery stenosis

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Cuilan Hou ◽  
Junmin Zheng ◽  
Wei liu ◽  
Lijian Xie ◽  
Xiaomin Sun ◽  
...  
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Pulmonary Artery ◽  
Molecular Mechanism ◽  
Protein Level ◽  
Congenital Heart ◽  
Artery Stenosis ◽  
Pulmonary Artery Stenosis ◽  
Functional Component ◽  
Functional Changes

AbstractCongenital heart defects, one of the most common birth defects, affect approximately 1% of live birth globally and remain the leading cause of infant mortality in developed countries. Utilizing the pathogenicity score and inheritance mode from whole exome sequencing results, a heterozygous mutation (NM_001278939.1: c.1939G>T, p.Gly647Ter) in elastin (ELN) was identified among 6,440 variants in a female proband born with an atrial septal defect accompanied by pulmonary artery stenosis. Results of RT-PCR showed that the mutation (NM_001278939.1: c.1939G>T, p.Gly647Ter) did not affect the expression levels of ELN mRNA but increased protein level. The content of ELN truncate (functional component) was significantly lower in both the intracellular and extracellular compartments after mutation. These results indicate that the ELN mutation (NM_001278939.1: c.1939G>T, p.Gly647Ter) affected the protein truncate, which may be a functional component of ELN and play crucial roles for this pedigree. Here we report of an ELN heterozygous variant associated with congenital heart disease accompanied with pulmonary artery stenosis, which is less common. Based on our results, we speculate that this may be the main molecular mechanism underlying the mutation-led functional changes, and propose that the decrease of ELN protein level may cause this pedigree vascular abnormality, especially pulmonary artery stenosis, and reinforce the view that ELN insufficiency is the primary cause of these vascular lesions. This may be the main molecular mechanism underlying the mutation-led functional changes. Thus, systematic analysis not only enables us to better understand the etiology of this disease but also contributes to clinical and prenatal diagnosis.

scholarly journals Correlation between cardiac catheterization and contrast enhanced MRI in pulmonary artery stenosis

2010 ◽  
Vol 12 (S1) ◽  
Author(s):  
Isra Valverde ◽  
Thomas Krasemann ◽  
Eric Rosenthal ◽  
Tarique Hussain ◽  
Hannah Bellsham-Revell ◽  
...  
Keyword(s):  
Pulmonary Artery ◽  
Cardiac Catheterization ◽  
Artery Stenosis ◽  
Pulmonary Artery Stenosis ◽  
Enhanced Mri ◽  
Contrast Enhanced ◽  
Contrast Enhanced Mri
Sign in / Sign up

Export Citation Format

Share Document