scholarly journals Structural basis for the recognition of superantigen streptococcal pyrogenic exotoxin A (SpeA1) by MHC class II molecules and T-cell receptors

1999 ◽  
Vol 18 (1) ◽  
pp. 9-21 ◽  
Author(s):  
A. C. Papageorgiou
Keyword(s):  
T Cell ◽  
Mhc Class Ii ◽  
T Cell Receptors ◽  
Class Ii ◽  
Structural Basis ◽  
Exotoxin A ◽  
Cell Receptors ◽  
Mhc Class Ii Molecules

Interactions of CD4 with MHC class II molecules, T cell receptors and p56 lck

1993 ◽  
Vol 342 (1299) ◽  
pp. 13-24 ◽  
Keyword(s):  
T Cell ◽  
Mhc Class Ii ◽  
T Cell Receptors ◽  
Protein Tyrosine Kinase ◽  
Cell Receptor ◽  
Class Ii ◽  
Cell Receptors ◽  
Multimeric Complex ◽  
And Function ◽  
Immunoglobulin Supergene Family

CD4 and CD8 are members of the immunoglobulin supergene family of proteins, and function as co-receptors with the T cell receptor (TCR) in binding MHC class II or class I molecules, respectively. Within this multimeric complex, CD4 interacts with three distinct ligands. CD4 interacts through its D1 and D2 domains with MHC class II proteins, through its D3 and D4 domains with T cell receptors, and through its cytoplasmic tail with p56 lck , a src -related, protein tyrosine kinase. Each of these interactions is important in the function of CD4 and will be discussed in turn.

scholarly journals Characterization of a library of twenty HBV-specific MHC class II-restricted T cell receptors

2021 ◽  
Author(s):  
Sophia Schreiber ◽  
Melanie Honz ◽  
Weeda Mamozai ◽  
Peter Kurktschiev ◽  
Matthias Schiemann ◽  
...  
Keyword(s):  
T Cell ◽  
Mhc Class Ii ◽  
T Cell Receptors ◽  
Class Ii ◽  
Cell Receptors

Characterization of MHC class II-restricted T-cell receptors for T-cell therapy of HBV infection

Cytotherapy ◽  
2019 ◽  
Vol 21 (5) ◽  
pp. S10
Author(s):  
S. Schreiber ◽  
M. Honz ◽  
M. Schiemann ◽  
C. Zielinski ◽  
U. Protzer ◽  
...  
Keyword(s):  
T Cell ◽  
Cell Therapy ◽  
Mhc Class Ii ◽  
T Cell Receptors ◽  
Class Ii ◽  
Hbv Infection ◽  
T Cell Therapy ◽  
Cell Receptors

scholarly journals Isolation of human MHC class II-restricted T cell receptors from the autologous T-cell repertoire with potent anti-leukaemic reactivity

Immunology ◽  
2012 ◽  
Vol 137 (3) ◽  
pp. 226-238 ◽  
Author(s):  
Luise U Weigand ◽  
Xiaoling Liang ◽  
Sabine Schmied ◽  
Sabine Mall ◽  
Richard Klar ◽  
...  
Keyword(s):  
T Cell ◽  
Mhc Class Ii ◽  
T Cell Receptors ◽  
Class Ii ◽  
T Cell Repertoire ◽  
Cell Repertoire ◽  
Cell Receptors

scholarly journals Peptide–MHC Binding Reveals Conserved Allosteric Sites in MHC Class I- and Class II-Restricted T Cell Receptors (TCRs)

2020 ◽  
Vol 432 (24) ◽  
pp. 166697 ◽  
Author(s):  
Yanan He ◽  
Pragati Agnihotri ◽  
Sneha Rangarajan ◽  
Yihong Chen ◽  
Melissa C. Kerzic ◽  
...  
Keyword(s):  
T Cell ◽  
Mhc Class I ◽  
T Cell Receptors ◽  
Class Ii ◽  
Class I ◽  
Cell Receptors ◽  
Allosteric Sites

Structural basis for the recognition of mutant self by a tumor-specific, MHC class II–restricted T cell receptor

2007 ◽  
Vol 8 (4) ◽  
pp. 398-408 ◽  
Author(s):  
Lu Deng ◽  
Ries J Langley ◽  
Patrick H Brown ◽  
Gang Xu ◽  
Leslie Teng ◽  
...  
Keyword(s):  
T Cell ◽  
T Cell Receptor ◽  
Mhc Class Ii ◽  
Cell Receptor ◽  
Class Ii ◽  
Structural Basis
Sign in / Sign up

Export Citation Format

Share Document