Selection of Vδ+ T Cell Receptors of Intestinal Intraepithelial Lymphocytes is Dependent on Class II Histocompatibility Antigen Expression

1991 ◽  
pp. 255-267 ◽  
Author(s):  
L. Lefrancois ◽  
R. LeCorre ◽  
Judy Mayo ◽  
J. A. Bluestone ◽  
T. Goodman
Keyword(s):  
T Cell ◽  
T Cell Receptors ◽  
Antigen Expression ◽  
Class Ii ◽  
Intraepithelial Lymphocytes ◽  
Histocompatibility Antigen ◽  
Cell Receptors ◽  
Intestinal Intraepithelial Lymphocytes ◽  
Selection Of

Diversity of γδ T-cell receptors on murine intestinal intraepithelial lymphocytes

Nature ◽  
1989 ◽  
Vol 339 (6227) ◽  
pp. 712-714 ◽  
Author(s):  
Yohtaroh Takagaki ◽  
Amy DeCloux ◽  
Marc Bonneville ◽  
Susumu Tonegawa
Keyword(s):  
T Cell ◽  
T Cell Receptors ◽  
Intraepithelial Lymphocytes ◽  
Γδ T Cell ◽  
Cell Receptors ◽  
Intestinal Intraepithelial Lymphocytes

scholarly journals Peptide–MHC Binding Reveals Conserved Allosteric Sites in MHC Class I- and Class II-Restricted T Cell Receptors (TCRs)

2020 ◽  
Vol 432 (24) ◽  
pp. 166697 ◽  
Author(s):  
Yanan He ◽  
Pragati Agnihotri ◽  
Sneha Rangarajan ◽  
Yihong Chen ◽  
Melissa C. Kerzic ◽  
...  
Keyword(s):  
T Cell ◽  
Mhc Class I ◽  
T Cell Receptors ◽  
Class Ii ◽  
Class I ◽  
Cell Receptors ◽  
Allosteric Sites

scholarly journals Qa-2–Dependent Selection of Cd8α/α T Cell Receptor α/β1 Cells in Murine Intestinal Intraepithelial Lymphocytes

2001 ◽  
Vol 193 (3) ◽  
pp. 413-414
Author(s):  
Gobardhan Das ◽  
Dina S. Gould ◽  
Mathew M. Augustine ◽  
Gladis Fragoso ◽  
Edda Sciutto ◽  
...  
Keyword(s):  
T Cell ◽  
T Cell Receptor ◽  
Cell Receptor ◽  
Intraepithelial Lymphocytes ◽  
Intestinal Intraepithelial Lymphocytes ◽  
Selection Of

Abstract 2564: Selection of affinity-enhanced T-cell receptors for adoptive T-cell therapy targeting MAGE-A10

2018 ◽  
Author(s):  
Ellen Border ◽  
Joseph P. Sanderson ◽  
Thomas Weissensteiner ◽  
Natalie Hyland ◽  
Tom Holdich ◽  
...  
Keyword(s):  
T Cell ◽  
Cell Therapy ◽  
T Cell Receptors ◽  
Adoptive T Cell Therapy ◽  
T Cell Therapy ◽  
Cell Receptors ◽  
Selection Of

scholarly journals Affinity-enhanced T-cell receptors for adoptive T-cell therapy targeting MAGE-A10: strategy for selection of an optimal candidate

2018 ◽  
Vol 8 (2) ◽  
pp. e1532759 ◽  
Author(s):  
Ellen C. Border ◽  
Joseph P. Sanderson ◽  
Thomas Weissensteiner ◽  
Andrew B. Gerry ◽  
Nicholas J. Pumphrey
Keyword(s):  
T Cell ◽  
Cell Therapy ◽  
T Cell Receptors ◽  
Adoptive T Cell Therapy ◽  
T Cell Therapy ◽  
Cell Receptors ◽  
Optimal Candidate ◽  
Selection Of

Interactions of CD4 with MHC class II molecules, T cell receptors and p56 lck

1993 ◽  
Vol 342 (1299) ◽  
pp. 13-24 ◽  
Keyword(s):  
T Cell ◽  
Mhc Class Ii ◽  
T Cell Receptors ◽  
Protein Tyrosine Kinase ◽  
Cell Receptor ◽  
Class Ii ◽  
Cell Receptors ◽  
Multimeric Complex ◽  
And Function ◽  
Immunoglobulin Supergene Family

CD4 and CD8 are members of the immunoglobulin supergene family of proteins, and function as co-receptors with the T cell receptor (TCR) in binding MHC class II or class I molecules, respectively. Within this multimeric complex, CD4 interacts with three distinct ligands. CD4 interacts through its D1 and D2 domains with MHC class II proteins, through its D3 and D4 domains with T cell receptors, and through its cytoplasmic tail with p56 lck , a src -related, protein tyrosine kinase. Each of these interactions is important in the function of CD4 and will be discussed in turn.

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