scholarly journals Crystal structure of the histone acetyltransferase domain of the human PCAF transcriptional regulator bound to coenzyme A

1999 ◽  
Vol 18 (13) ◽  
pp. 3521-3532 ◽  
Author(s):  
A. Clements
Keyword(s):  
Crystal Structure ◽  
Histone Acetyltransferase ◽  
Coenzyme A ◽  
Transcriptional Regulator ◽  
Acetyltransferase Domain

scholarly journals Crystal structure of a binary complex between human GCN5 histone acetyltransferase domain and acetyl coenzyme A

2007 ◽  
Vol 68 (1) ◽  
pp. 403-407 ◽  
Author(s):  
Anja Schuetz ◽  
Galina Bernstein ◽  
Aiping Dong ◽  
Tatiana Antoshenko ◽  
Hong Wu ◽  
...  
Keyword(s):  
Crystal Structure ◽  
Histone Acetyltransferase ◽  
Coenzyme A ◽  
Binary Complex ◽  
Acetyl Coenzyme A ◽  
Acetyl Coenzyme ◽  
Acetyltransferase Domain

scholarly journals The Human Monocytic Leukemia Zinc Finger Histone Acetyltransferase Domain Contains DNA-binding Activity Implicated in Chromatin Targeting

2007 ◽  
Vol 282 (50) ◽  
pp. 36603-36613 ◽  
Author(s):  
Marc A. Holbert ◽  
Timothy Sikorski ◽  
Juliana Carten ◽  
Danielle Snowflack ◽  
Santosh Hodawadekar ◽  
...  
Keyword(s):  
Dna Binding ◽  
Zinc Finger ◽  
Histone Acetyltransferase ◽  
Binding Activity ◽  
Monocytic Leukemia ◽  
Dna Binding Activity ◽  
Human Monocytic Leukemia ◽  
Acetyltransferase Domain

scholarly journals Crystal structure of the N-terminal domain of VqsR fromPseudomonas aeruginosaat 2.1 Å resolution

2017 ◽  
Vol 73 (7) ◽  
pp. 431-436
Author(s):  
Qing He ◽  
Kang Wang ◽  
Tiantian Su ◽  
Feng Wang ◽  
Lichuan Gu ◽  
...  
Keyword(s):  
Crystal Structure ◽  
Sequence Similarity ◽  
Transcriptional Regulator ◽  
Binding Domain ◽  
Structural Comparison ◽  
Homoserine Lactones ◽  
Terminal Domain ◽  
C Terminus ◽  
Common Motif ◽  
The Common

VqsR is a quorum-sensing (QS) transcriptional regulator which controls QS systems (las,rhlandpqs) by directly downregulating the expression ofqscRinPseudomonas aeruginosa. As a member of the LuxR family of proteins, VqsR shares the common motif of a helix–turn–helix (HTH)-type DNA-binding domain at the C-terminus, while the function of its N-terminal domain remains obscure. Here, the crystal structure of the N-terminal domain of VqsR (VqsR-N; residues 1–193) was determined at a resolution of 2.1 Å. The structure is folded into a regular α–β–α sandwich topology, which is similar to the ligand-binding domain (LBD) of the LuxR-type QS receptors. Although their sequence similarity is very low, structural comparison reveals that VqsR-N has a conserved enclosed cavity which could recognize acyl-homoserine lactones (AHLs) as in other LuxR-type AHL receptors. The structure suggests that VqsR could be a potential AHL receptor.

scholarly journals Crystal Structure of the Sugar Binding Domain of the Archaeal Transcriptional Regulator TrmB

2006 ◽  
Vol 281 (16) ◽  
pp. 10976-10982 ◽  
Author(s):  
Michael Krug ◽  
Sung-Jae Lee ◽  
Kay Diederichs ◽  
Winfried Boos ◽  
Wolfram Welte
Keyword(s):  
Crystal Structure ◽  
Transcriptional Regulator ◽  
Binding Domain ◽  
Sugar Binding

Crystal Structure of Dephospho-Coenzyme A Kinase from Haemophilus influenzae

2001 ◽  
Vol 136 (2) ◽  
pp. 119-125 ◽  
Author(s):  
Galina Obmolova ◽  
Alexey Teplyakov ◽  
Nicklas Bonander ◽  
Edward Eisenstein ◽  
Andrew J Howard ◽  
...  
Keyword(s):  
Crystal Structure ◽  
Haemophilus Influenzae ◽  
Coenzyme A

Screening of a large Rubinstein–Taybi cohort identified many novel variants and emphasizes the importance of the CREBBP histone acetyltransferase domain

2020 ◽  
Vol 182 (11) ◽  
pp. 2508-2520
Author(s):  
Esther Cross ◽  
Philippa J. Duncan‐Flavell ◽  
Rachel J. Howarth ◽  
James I. Hobbs ◽  
Nicholas Simon Thomas ◽  
...  
Keyword(s):  
Histone Acetyltransferase ◽  
Novel Variants ◽  
Acetyltransferase Domain

The 1.75 Å Crystal Structure of Acetyl-CoA Synthetase Bound to Adenosine-5‘-propylphosphate and Coenzyme A†

Biochemistry ◽  
2003 ◽  
Vol 42 (10) ◽  
pp. 2866-2873 ◽  
Author(s):  
Andrew M. Gulick ◽  
Vincent J. Starai ◽  
Alexander R. Horswill ◽  
Kristen M. Homick ◽  
Jorge C. Escalante-Semerena
Keyword(s):  
Crystal Structure ◽  
Coenzyme A ◽  
Acetyl Coa

scholarly journals Crystal structure of FadR, a fatty acid-responsive transcription factor with a novel acyl coenzyme A-binding fold

2000 ◽  
Vol 19 (19) ◽  
pp. 5167-5177 ◽  
Author(s):  
D.M.F van Aalten ◽  
C.C. DiRusso ◽  
J. Knudsen ◽  
R.K. Wierenga
Keyword(s):  
Crystal Structure ◽  
Transcription Factor ◽  
Fatty Acid ◽  
Coenzyme A ◽  
Acyl Coenzyme A

Crystal structure of YfiR, an unusual TetR/CamR-type putative transcriptional regulator from Bacillus subtilis

2006 ◽  
Vol 65 (1) ◽  
pp. 255-257 ◽  
Author(s):  
Shyamala S. Rajan ◽  
Xiaojing Yang ◽  
Ludmilla Shuvalova ◽  
Frank Collart ◽  
Wayne F. Anderson
Keyword(s):  
Crystal Structure ◽  
Bacillus Subtilis ◽  
Transcriptional Regulator
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