scholarly journals Biomarkers in inherited arrhythmias: necessity for validation and collaboration

2020 ◽  
Vol 41 (47) ◽  
pp. 4523-4524
Author(s):  
Arthur A M Wilde ◽  
Elisabeth M Lodder
Keyword(s):  
Inherited Arrhythmias

Investigating inherited arrhythmias using hiPSC-derived cardiomyocytes

Methods ◽  
2021 ◽  
Author(s):  
Alia Arslanova ◽  
Sanam Shafaattalab ◽  
Eric Lin ◽  
Tiffany Barszczewski ◽  
Leif Hove-Madsen ◽  
...  
Keyword(s):  
Inherited Arrhythmias

scholarly journals Inherited Arrhythmias

Circulation ◽  
2007 ◽  
Vol 116 (20) ◽  
pp. 2325-2345 ◽  
Author(s):  
Stephan E. Lehnart ◽  
Michael J. Ackerman ◽  
D. Woodrow Benson ◽  
Ramon Brugada ◽  
Colleen E. Clancy ◽  
...  
Keyword(s):  
Inherited Arrhythmias

Inherited Arrhythmias: Brugada Syndrome and Early Repolarisation Syndrome

2018 ◽  
pp. 437-480
Author(s):  
Pieter G. Postema ◽  
Krystien V. V. Lieve ◽  
Arthur A. M. Wilde
Keyword(s):  
Brugada Syndrome ◽  
Inherited Arrhythmias

Inherited arrhythmias and conduction disorders

2020 ◽  
pp. 245-286
Author(s):  
Perry Elliott ◽  
Pier D. Lambiase ◽  
Dhavendra Kumar
Keyword(s):  
Ventricular Tachycardia ◽  
Beta Blockers ◽  
Calcium Handling ◽  
Polymorphic Ventricular Tachycardia ◽  
Beta Blockade ◽  
Na Channel ◽  
Conduction Disorders ◽  
Younger Age ◽  
Channel Currents ◽  
Inherited Arrhythmias

Long QT syndrome is primarily a disorder of repolarization with three principal ion channel currents accounting for the condition. Management revolves around optimization of beta blockade and avoidance of triggers with implantable cardiac defibrillators (ICD) recommended in high risk cases. Brugada syndrome is thought to be caused by Na channel mutations although the aetiology is not fully established. Controversy exists regarding optimal risk stratification approaches. Catecholaminergic polymorphic ventricular tachycardia is caused by abnormalities in calcium handling leading to bidirectional ventricular tachycardia/VF and can be managed using medication –principally beta blockers and occasionally sympathectomy with ICD in cardiac arrest survivors with specific caveats. Inherited conduction disorders should always be considered in patients presenting at a younger age with conduction disease paying specific attention to lamin mutations where an ICD will need to be considered.

scholarly journals Molecular Mechanisms of Inherited Arrhythmias

2008 ◽  
Vol 9 (3) ◽  
pp. 160-168 ◽  
Author(s):  
Cordula Wolf ◽  
Charles Berul
Keyword(s):  
Molecular Mechanisms ◽  
Inherited Arrhythmias

scholarly journals Health status in patients at risk of inherited arrhythmias and sudden unexpected death compared to the general population

2010 ◽  
Vol 11 (1) ◽  
Author(s):  
Anniken Hamang ◽  
Geir Egil Eide ◽  
Karin Nordin ◽  
Berit Rokne ◽  
Cathrine Bjorvatn ◽  
...  
Keyword(s):  
At Risk ◽  
Health Status ◽  
General Population ◽  
Sudden Unexpected Death ◽  
Unexpected Death ◽  
Patients At Risk ◽  
Inherited Arrhythmias

Decreased Density of Itoin Left Ventricular Myocytes from German Shepherd Dogs with Inherited Arrhythmias

1997 ◽  
Vol 8 (8) ◽  
pp. 872-883 ◽  
Author(s):  
LISA C. FREEMAN ◽  
LINDA M. PACIORETTY ◽  
N. SYDNEY MOISE ◽  
ROBERT S. KASS ◽  
ROBERT F. GILMOUR
Keyword(s):  
Ventricular Myocytes ◽  
Left Ventricular ◽  
German Shepherd ◽  
Inherited Arrhythmias
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