scholarly journals Iron deficiency is associated with impaired quality of life in non-anaemic patients hospitalized for acute decompensated heart failure

2013 ◽  
Vol 34 (suppl 1) ◽  
pp. 1728-1728
Author(s):  
F. Hammer ◽  
S. Stauffenberg ◽  
H. Faller ◽  
G. Ertl ◽  
S. Stoerk ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Heart Failure ◽  
Iron Deficiency ◽  
Acute Decompensated Heart Failure ◽  
Decompensated Heart Failure ◽  
Impaired Quality

Medical Resource Use, Costs, and Quality of Life in Patients With Acute Decompensated Heart Failure: Findings From ASCEND-HF

2013 ◽  
Vol 19 (9) ◽  
pp. 611-620 ◽  
Author(s):  
Shelby D. Reed ◽  
Padma Kaul ◽  
Yanhong Li ◽  
Zubin J. Eapen ◽  
Linda Davidson-Ray ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Heart Failure ◽  
Resource Use ◽  
Acute Decompensated Heart Failure ◽  
Decompensated Heart Failure ◽  
Medical Resource

Abstract P160: Relationship of Physical Function and Quality of Life in Elderly Patients With Acute Decompensated Heart Failure: The Rehabilitation Therapy in Older Acute Heart Failure Patients (The REHAB-HF Trial)

Circulation ◽  
2018 ◽  
Vol 137 (suppl_1) ◽  
Author(s):  
Amer I Aladin ◽  
David Whellan ◽  
Robert Mentz ◽  
Gordon Reeves ◽  
Pamela Duncan ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Heart Failure ◽  
Physical Function ◽  
Acute Decompensated Heart Failure ◽  
Nyha Class ◽  
Decompensated Heart Failure ◽  
Walking Distance ◽  
High Risk Population ◽  
Rehabilitation Therapy

Introduction: Older patients with acute decompensated heart failure (ADHF) have impaired physical function (PF) and reduced quality of life (QOL). However, the relationship between impairments in PF and QOL are unknown but relevant to clinical practice and design of targeted intervention trials in this high-risk population. Methods: We assessed 202 consecutive patients hospitalized with ADHF in the multicenter Rehabilitation Therapy in Older Acute HF Patients (REHAB-HF) Trial. Standard measures of PF included the Short Physical Performance Battery (SPPB), a validated PF outcome measure in frail elderly, and 6-minute Walking Distance (6MWD). QOL was assessed by Kansas City Cardiomyopathy Questionnaire (KCCQ). Pearson’s correlation statistics examined associations between PF and QOL. Stepwise regressions were performed to identify independent predictors of QOL including PF measures, demographics, and disease severity indicators (NYHA class, previous hospitalizations, duration of current hospitalization, and number of HF signs and symptoms). Results: Participants were 72±7.5 years, BMI 33.2±8.8 kg/m 2 , 54% women, 52% non-white, 52% with reduced ejection fraction, and 44% with previous hospitalizations within 6 months. Participants had marked deficits in PF (SPPB 6.0±2.5 units, 6MWD 185±99 meters) and low QOL (KCCQ Physical Limitation Score (PLS) 47.3±23.8). There were modest but highly significant correlations of QOL measures with SPPB, 6MWD, and number of HF symptoms and signs (Table). Using stepwise regressions, 6MWD and BMI were modest, significant independent predictors of QOL (partial r=0.18, p=0.012 and partial r=-0.27, p=0.0003, respectively), while SPPB, demographics, and HF severity indicators were not. Conclusion: In older, hospitalized ADHF patients, PF and QOL are both severely impaired, but are only modestly related. PF and QOL assess unique domains of impairment and provide complementary information for characterizing clinically meaningful patient-oriented outcomes in ADHF.

scholarly journals Cognition, Physical Function, and Quality of Life in Older Patients With Acute Decompensated Heart Failure

2020 ◽  
Author(s):  
Amy M. Pastva ◽  
Christina E. Hugenschmidt ◽  
Dalane W. Kitzman ◽  
M. Benjamin Nelson ◽  
Gretchen A. Brenes ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Heart Failure ◽  
Physical Function ◽  
Older Patients ◽  
Acute Decompensated Heart Failure ◽  
Decompensated Heart Failure

scholarly journals PROGNOSTIC VALUE OF SOME INDICES OF LIFE QUALITY IN PATIENTS WITH ACUTE DECOMPENSATED HEART FAILURE IN CORRELATION WITH INFLAMMATORY STRESS MARKER

2017 ◽  
Vol 9 (2) ◽  
pp. 73-77
Author(s):  
V A Kostenko ◽  
E A Skorodumova ◽  
E G Skorodumova ◽  
A V Rysev ◽  
N A Dymnikova
Keyword(s):  
Quality Of Life ◽  
Heart Failure ◽  
Acute Decompensated Heart Failure ◽  
Life Quality ◽  
Decompensated Heart Failure ◽  
Medium Term ◽  
Inflammatory Stress ◽  
Stress Markers ◽  
Correlation Data

The article describes the study of the quality of life in patients with acute decompensated heart fail- ure and comparison of data and a visual analogue scale of Kansas questionnaire in patients with acute decompensated heart failure and also their correlation with known prognostic factors such as level of inflammatory stress markers. Since there can not be a 'gold standard' profiles, their validity can be estimated taking into account the coefficient of correlation data profiles with the prognosis. To assess the quality of life parameters, a Kansas questionnaire was used. Each item was evaluated by patients in1 to 6 points.. Prognostically unfavorable in the questionnaire were the marks from 1 to 3. According to the results of the study, it was shown that the QOL questionnaire can serve not only as a marker for assessing the patient's treatment, but also as an indicator of the medium-term vital prognosis. Correla- tion of these parameters of QOL with objective parameters reflecting the function of the left ventricle, comorbid status (primarily, the state of the kidneys), as well as signs of inflammatory stress are noted.

scholarly journals State-of-the-art Structural Interventions in Heart Failure

2019 ◽  
Vol 5 (3) ◽  
pp. 147-154 ◽  
Author(s):  
Jeffrey Park ◽  
Hussam S Suradi
Keyword(s):  
Heart Failure ◽  
Acute Decompensated Heart Failure ◽  
Structural Heart Disease ◽  
Decompensated Heart Failure ◽  
Structural Interventions ◽  
The Past ◽  
Effective Interventions ◽  
The Us ◽  
Multiple Trials

Heart failure (HF) is a leading cause of hospitalisation and healthcare costs worldwide. Acute decompensated heart failure accounts for more than 1 million hospitalisations in the US. Despite advances in the quality of acute and chronic HF disease management, gaps in knowledge about effective interventions to support the transition of care for patients with HF remain. Despite multiple trials of promising therapies, standard care consists of decongestion with IV diuretics and haemodynamic support with vasodilators and inotropes and this has remained largely unchanged during the past 45 years. Newer advances in medical innovations and structural heart disease interventions have now given promise to improved survival, outcomes and quality of life for patients with advanced HF of multiple aetiologies. In this article, we focus on structural interventions in the treatment of patients with HF.

scholarly journals Iron deficiency after kidney transplantation

2020 ◽  
Author(s):  
Joanna Sophia J Vinke ◽  
Marith I Francke ◽  
Michele F Eisenga ◽  
Dennis A Hesselink ◽  
Martin H de Borst
Keyword(s):  
Quality Of Life ◽  
Heart Failure ◽  
Immune System ◽  
Iron Deficiency ◽  
Patient Outcomes ◽  
Excess Mortality ◽  
Transplant Recipients ◽  
Kidney Transplant Recipients ◽  
The Impact

Abstract Iron deficiency (ID) is highly prevalent in kidney transplant recipients (KTRs) and has been independently associated with an excess mortality risk in this population. Several causes lead to ID in KTRs, including inflammation, medication and an increased iron need after transplantation. Although many studies in other populations indicate a pivotal role for iron as a regulator of the immune system, little is known about the impact of ID on the immune system in KTRs. Moreover, clinical trials in patients with chronic kidney disease or heart failure have shown that correction of ID, with or without anaemia, improves exercise capacity and quality of life, and may improve survival. ID could therefore be a modifiable risk factor to improve graft and patient outcomes in KTRs; prospective studies are warranted to substantiate this hypothesis.

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