Association of age at first drink and first alcohol intoxication as predictors of mortality: a birth cohort study

Abstract Background More information on the health-related repercussions of age at onset of adolescent drinking is needed. The aim of this study was to examine the associations between self-reported age at first drink and age at first alcohol intoxication with the risk of death by age 30. Methods The sample (n = 6564; 49.1% males) included all participants of the Northern Finland Birth Cohort Study 1986 (NFBC1986) for whom the two measures of adolescent drinking were available. Self-reported age at onset of first drink and first alcohol intoxication were analyzed along with background variables and data regarding subsequent psychiatric diagnoses. Adolescents were dichotomized into those reporting age at first drink and age at first intoxication before or after age 14. Cox regression was used to calculate hazard ratios (HRs) with 95% confidence interval (95% CI) for death by age 30. Results By the age of 30, 0.7% (n = 47) of all 6564 participants were deceased. In the multivariable models, male gender and a history of illicit substance use in adolescence were associated with both all-cause mortality and mortality due to accidents or suicide. After controlling for confounding variables, age at first alcohol intoxication was associated with all-cause mortality (HR 2.33; 95% CI 1.04–5.20) as well as death due to accidents or suicide (HR 2.99; 95% CI 1.11–8.05). Conclusions Earlier age at first intoxication carries long-term repercussions with respect to premature loss of life. Efforts should be made targeting the prolongation of initiating binge drinking in adolescence to diminish this mortality risk.

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Physical heaviness of work and sitting at work as predictors of mortality: a 26-year follow-up of the Helsinki Birth Cohort Study

BMJ Open ◽

10.1136/bmjopen-2018-026280 ◽

2019 ◽

Vol 9 (5) ◽

pp. e026280 ◽

Cited By ~ 4

Author(s):

Tuija M Mikkola ◽

Mikaela B von Bonsdorff ◽

Minna K Salonen ◽

Hannu Kautiainen ◽

Leena Ala-Mursula ◽

...

Keyword(s):

Cohort Study ◽

Birth Cohort ◽

Cardiovascular Mortality ◽

National Level ◽

Secondary Outcome ◽

Birth Cohort Study ◽

Specific Level ◽

Risk Of Death ◽

All Cause Mortality

ObjectivesTo examine the relationships of late-career physical heaviness of work and sitting at work with mortality. A national-level job exposure matrix was used to determine the occupation-specific level of physical heaviness and sitting.DesignProspective cohort study between years 1990 and 2015.SettingCommunity.Participants5210 men and 4725 women from the Helsinki Birth Cohort Study with an occupational code at baseline (ages 45–57 years).Primary and secondary outcome measuresTotal, cardiovascular (International Classification of Diseases 10th Revision I00–I99), cancer (C00–C97) and external (S00–Y84) mortality.ResultsThe exposures, physical heaviness and sitting had a non-linear, inverse relationship. During the 26-year follow-up, 1536 men and 759 women died. Among men, physical heaviness of work was positively associated and sitting at work was negatively associated with all-cause, cardiovascular and external cause mortality but they were not associated with cancer mortality. The HRs for men in the highest quartile of physical heaviness of work compared with men in the lowest quartile were 1.54 (1.31–1.80) for all-cause mortality, 1.70 (1.30–2.23) for cardiovascular mortality and 3.18 (1.75–5.78) for external cause mortality (adjusted for age and years of education). Compared with the lowest quartile, the HRs for the highest quartile of sitting at work among men were 0.71 (0.61–0.82) for all-cause mortality, 0.59 (0.45–0.77) for cardiovascular mortality and 0.38 (0.22–0.66) for external cause mortality. In women, neither physical heaviness of work nor sitting at work was associated with mortality.ConclusionsMen in physically heavy work at their late-work career are at higher risk of death than men in physically light work.

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Organic food consumption during pregnancy is associated with different food intake and health-related characteristics: the KOALA Birth Cohort Study

10.1055/s-0037-1608303 ◽

2017 ◽

Author(s):

APS Simões-Wüst ◽

C Moltó-Puigmartí ◽

E Jansen ◽

M van Dongen ◽

P Dagnelie ◽

...

Keyword(s):

Cohort Study ◽

Food Intake ◽

Birth Cohort ◽

Food Consumption ◽

Organic Food ◽

Birth Cohort Study ◽

Health Related ◽

Organic Food Consumption

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Body composition and changes in health-related quality of life in older age: a 10-year follow-up of the Helsinki Birth Cohort Study

Quality of Life Research ◽

10.1007/s11136-020-02453-1 ◽

2020 ◽

Vol 29 (8) ◽

pp. 2039-2050

Author(s):

Tuija M. Mikkola ◽

Hannu Kautiainen ◽

Mikaela B. von Bonsdorff ◽

Minna K. Salonen ◽

Niko Wasenius ◽

...

Keyword(s):

Quality Of Life ◽

Body Composition ◽

Cohort Study ◽

Birth Cohort ◽

Birth Cohort Study ◽

Health Related Quality ◽

Related Quality ◽

Health Related

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Oral health-related behaviours do not mediate the effect of maternal education on adolescents' gingival bleeding: A birth cohort study

Community Dentistry And Oral Epidemiology ◽

10.1111/cdoe.12350 ◽

2017 ◽

Vol 46 (2) ◽

pp. 169-177 ◽

Cited By ~ 5

Author(s):

Marco A. Peres ◽

Gustavo G. Nascimento ◽

Karen G. Peres ◽

Flavio F. Demarco ◽

Ana B. Menezes

Keyword(s):

Cohort Study ◽

Oral Health ◽

Birth Cohort ◽

Maternal Education ◽

Birth Cohort Study ◽

Gingival Bleeding ◽

Health Related

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Socioeconomic inequalities in circulatory and all-cause mortality after retirement: the impact of mid-life income and old-age pension. Evidence from the Uppsala Birth Cohort Study

Journal of Epidemiology & Community Health ◽

10.1136/jech.2010.131177 ◽

2011 ◽

Vol 66 (7) ◽

pp. e16-e16 ◽

Cited By ~ 19

Author(s):

Stefan Fors ◽

Bitte Modin ◽

Ilona Koupil ◽

Denny Vågerö

Keyword(s):

Cohort Study ◽

Birth Cohort ◽

Old Age ◽

Socioeconomic Inequalities ◽

Birth Cohort Study ◽

All Cause Mortality ◽

The Impact

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Mental health related determinants of parenting stress among urban mothers of young children – results from a birth-cohort study in Ghana and Côte d’Ivoire

BMC Psychiatry ◽

10.1186/1471-244x-14-156 ◽

2014 ◽

Vol 14 (1) ◽

Cited By ~ 9

Author(s):

Nan Guo ◽

◽

Carola Bindt ◽

Marguerite Te Bonle ◽

John Appiah-Poku ◽

...

Keyword(s):

Mental Health ◽

Cohort Study ◽

Young Children ◽

Parenting Stress ◽

Birth Cohort ◽

Cote D'ivoire ◽

Côte D’Ivoire ◽

Birth Cohort Study ◽

Urban Mothers ◽

Health Related

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Migraine as a predictor of mortality: The HUNT study

Cephalalgia ◽

10.1177/0333102415593090 ◽

2015 ◽

Vol 36 (4) ◽

pp. 351-357 ◽

Cited By ~ 9

Author(s):

Anders Nikolai Åsberg ◽

Lars Jacob Stovner ◽

John-Anker Zwart ◽

Bendik Slagsvold Winsvold ◽

Ingrid Heuch ◽

...

Keyword(s):

Cohort Study ◽

Cardiovascular Mortality ◽

Cox Regression ◽

Population Based ◽

Risk Of Death ◽

Hazard Ratios ◽

All Cause Mortality ◽

Large Prospective Cohort Study ◽

Migrainous Headache

Background There is conflicting evidence for the association between migraine and increased mortality risk. The aim of this study was to investigate the relationship between migraine and non-migrainous headache, and all-cause mortality and cardiovascular mortality. Methods In this prospective population-based cohort study from Norway, we used baseline data from the second Nord-Trøndelag Health Survey (HUNT2), performed between 1995 and 1997 in the County of Nord-Trøndelag. These data were linked with a comprehensive mortality database with follow-up through the year 2011. A total of 51,853 (56% of invited) people were categorized based on their answers to the headache questions in HUNT2 (headache free, migraine or non-migrainous headache). Hazard ratios (HRs) of mortality during a mean of 14.1 years of follow-up were estimated using Cox regression. Results During the follow-up period 9408 died, 4321 of these from cardiovascular causes. There was no difference in all-cause mortality between individuals with migraine and non-migrainous headache compared to those without headache or between headache status and mortality by cardiovascular disease. There was, however, among men with migraine without aura a reduced risk of death by cardiovascular diseases (HR 0.72, 95% confidence interval 0.56–0.93). This relationship was not evident in women. Conclusion In this large, prospective cohort study there was no evidence for a higher all-cause mortality or cardiovascular mortality among individuals with migraine.

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Avoidable deaths in the first four years of life among children in the 2004 Pelotas (Brazil) birth cohort study

Cadernos de Saúde Pública ◽

10.1590/s0102-311x2011001400007 ◽

2011 ◽

Vol 27 (suppl 2) ◽

pp. s185-s197 ◽

Cited By ~ 6

Author(s):

Iná S. Santos ◽

Alicia Matijasevich ◽

Aluísio J. D. Barros ◽

Elaine P. Albernaz ◽

Marlos Rodrigues Domingues ◽

...

Keyword(s):

Cohort Study ◽

Prenatal Care ◽

Birth Cohort ◽

Health Care Quality ◽

Family Income ◽

Care Quality ◽

Birth Cohort Study ◽

Avoidable Deaths ◽

Risk Of Death ◽

Increased Risk

Avoidable deaths have been employed as indicators of health care quality. The aim of this study was to identify factors associated with avoidable deaths from birth to four years of age among children from the 2004 Pelotas (Brazil) birth cohort study. From January 1st, 2004, to December 31st, 2005, deaths were monitored on a daily basis and the causes were investigated and classified according to avoidability. After the first year, deaths were monitored through the Mortality Information System. A total of 94 children died during this period. It was possible to classify 92 deaths, 70 of which were preventable. Low family income, fewer prenatal visits and poor-quality prenatal care, preterm birth, low 5-minute Apgar score, and no breastfeeding in the first 24 hours of life were associated with increased risk of death. Prematurity was present in 39 deaths, but only five of these would have been prevented by measures provided during prenatal care. Although limited, compliance with antenatal care program guidelines is still the most important strategy for preventing avoidable deaths in childhood, particularly among the poorest children.

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