scholarly journals Parents survive longer after stroke than childless individuals: a prospective cohort study of Swedes over the age of 65

2019 ◽  
Vol 29 (6) ◽  
pp. 1090-1095
Author(s):  
Anna C Meyer ◽  
Jenny Torssander ◽  
Mats Talbäck ◽  
Karin Modig

Abstract Background Parents have lower mortality than childless individuals, and one possible explanation is support provided by adult children. Since stroke often results in functional limitations, support from children may be of particular importance. Here, we examine whether the presence of children matters for survival after stroke among older Swedish men and women. Methods This prospective cohort study linked data from several Swedish population registers. Individuals aged 65 years and older hospitalized for their first ischemic stroke between 1998 and 2002 (33 960 men and 36 189 women) were followed 12 years for survival. Hazard ratios for all-cause mortality were calculated by number of children using Cox proportional hazard regression stratified by sex and marital status and adjusted for education, income and comorbidities. Results Childlessness and having only one child was associated with higher mortality after stroke compared with having two children among men and women. The relative survival disadvantage of childless individuals was largest among married women [HR 1.28 (1.18–1.39)] and smallest among married men [1.09 (1.03–1.15)]. The differences in predicted median survival between childless individuals and those with two children were 4 and 7 months among married and unmarried men, and 15 and 9 months among married and unmarried women, respectively. Conclusions Having children is associated with a longer survival after stroke among men and women regardless of marital status. Our findings further suggest that the presence of children is especially connected to married women’s survival. These results may have implications for the improvement of informal care for childless older individuals.

2019 ◽  
Vol 95 (7) ◽  
pp. 505-510 ◽  
Author(s):  
Genevieve A F S van Liere ◽  
Christian J P A Hoebe ◽  
Jeanne AMC Dirks ◽  
Petra FG Wolffs ◽  
Nicole H T M Dukers-Muijrers

ObjectiveChlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) infections can clear without treatment. Despite high prevalence of anorectal infections in men who have sex with men (MSM) and women, studies on anorectal clearance are scarce. Moreover it is unknown whether bacterial load affects urogenital/anorectal CT clearance. In this prospective cohort study, CT and NG clearance is assessed at three anatomical sites of men and women.MethodsCT-positive and NG-positive MSM, heterosexual men and women ≥18 years of age visiting our STI clinic between 2011 and 2013 underwent a repeat test when returning for treatment (n=482). The primary outcome was clearance, defined as a positive nucleic acid amplification test (NAAT) at screening-consultation, followed by a negative NAAT at treatment-consultation. Sociodemographics, sexual risk behaviour and CT bacterial load (inhouse quantitative PCR) were tested as determinants for clearance using multivariable logistic regression for CT and Fisher’s exact test for NG.ResultsCT clearance was 9.1% (10/110) for urine, 6.8% (20/292) for vaginal swabs, 12.7% (8/63) for anorectal swabs (ie, 4.0% [1/25] in MSM and 18.4% [7/38] in women) and 57.1% (4/7) for oropharyngeal swabs. For NG this was 33.3% (2/6), 28.6% (2/7), 20.0% (2/10) and 27.3% (6/22), respectively. The number of days between tests (median 10, IQR 7–14) was not associated with clearance. Lower bacterial load at screening was the only predictor for CT clearance (urine mean 1.2 vs 2.6 log CT/mL, p=0.001; vaginal swabs mean 2.1 vs 5.2 log CT/mL p<0.0001; anorectal swabs mean 2.0 vs 3.7 log CT/mL, p=0.002). None of the tested determinants were associated with NG clearance.ConclusionsThis study reports the largest number of anorectal infections tested for CT and NG clearance to date. Clearance in all sample types was substantial: between 7% and 57% for CT, and between 20% and 33% for NG (notwithstanding low absolute numbers). CT clearance was associated with a lower load at screening. However, not all individuals with low bacterial CT load cleared the infection, hampering STI guideline change.


BMJ ◽  
2016 ◽  
pp. i5855 ◽  
Author(s):  
Nicola Veronese ◽  
Yanping Li ◽  
JoAnn E Manson ◽  
Walter C Willett ◽  
Luigi Fontana ◽  
...  

PLoS ONE ◽  
2016 ◽  
Vol 11 (9) ◽  
pp. e0163754 ◽  
Author(s):  
Tone Bull Enger ◽  
Hilde Pleym ◽  
Roar Stenseth ◽  
Guri Greiff ◽  
Alexander Wahba ◽  
...  

2006 ◽  
Vol 37 (05) ◽  
pp. 705 ◽  
Author(s):  
TELLERVO KORHONEN ◽  
ULLA BROMS ◽  
JYRKI VARJONEN ◽  
KALLE ROMANOV ◽  
MARKKU KOSKENVUO ◽  
...  

BMJ ◽  
2020 ◽  
pp. m2984 ◽  
Author(s):  
Linda L Magnusson Hanson ◽  
Anna Nyberg ◽  
Ellenor Mittendorfer-Rutz ◽  
Fredrik Bondestam ◽  
Ida E H Madsen

Abstract Objective To analyse the relation between exposure to workplace sexual harassment and suicide, as well as suicide attempts. Design Prospective cohort study. Setting Sweden. Participants 86 451 men and women of working age in paid work across different occupations responded to a self-report questionnaire including exposure to work related sexual harassment between 1995 and 2013. The analytical sample included 85 205 people with valid data on sexual harassment, follow-up time, and age. Main outcome measures Suicide and suicide attempts ascertained from administrative registers (mean follow-up time 13 years). Results Among the people included in the respective analyses of suicide and suicide attempts, 125 (0.1%) died from suicide and 816 (1%) had a suicide attempt during follow-up (rate 0.1 and 0.8 cases per 1000 person years). Overall, 11 of 4095 participants exposed to workplace sexual harassment and 114 of 81 110 unexposed participants committed suicide, and 61/4043 exposed and 755/80 513 unexposed participants had a record of suicide attempt. In Cox regression analyses adjusted for a range of sociodemographic characteristics, workplace sexual harassment was associated with an excess risk of both suicide (hazard ratio 2.82, 95% confidence interval 1.49 to 5.34) and suicide attempts (1.59, 1.21 to 2.08), and risk estimates remained significantly increased after adjustment for baseline health and certain work characteristics. No obvious differences between men and women were found. Conclusions The results support the hypothesis that workplace sexual harassment is prospectively associated with suicidal behaviour. This suggests that suicide prevention considering the social work environment may be useful. More research is, however, needed to determine causality, risk factors for workplace sexual harassment, and explanations for an association between work related sexual harassment and suicidal behaviour.


2009 ◽  
Vol 27 (4) ◽  
pp. 485-493 ◽  
Author(s):  
Andrew W. Roddam ◽  
Paul Appleby ◽  
Rachel Neale ◽  
Mitch Dowsett ◽  
Elizabeth Folkerd ◽  
...  

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