scholarly journals COMPUTERIZED MEIOTIC MAPPING IN ASPERGILLUS NIDULANS

Genetics ◽  
1972 ◽  
Vol 72 (4) ◽  
pp. 595-605
Author(s):  
Gordon L Dorn

ABSTRACT A computer system for the storage and processing of microbial meiotic data has been developed. Based on the language Fortran 4, the program retrieves relevant data and determines the order, map distances, and coefficient of coincidence for any three-gene group. Meiotic data from Aspergillus nidulans were used to test the program. A total of 61 three-gene sequences were processed, and the results were found to be compatible with the published values. The advantages and disadvantages of computer analysis for genetic analysis are discussed.

1968 ◽  
Vol 5 (3) ◽  
pp. 312-318 ◽  
Author(s):  
Charles S. Mayer

A computer analysis of inputs supplied by interviewers provides a set of management statistics that explains reasons for high-cost interviewer performance.


2017 ◽  
Vol 29 (5) ◽  
pp. 727-736 ◽  
Author(s):  
Jaipal S. Choudhary ◽  
Naiyar Naaz ◽  
Moanaro Lemtur ◽  
Bikash Das ◽  
Arun Kumar Singh ◽  
...  

1965 ◽  
Vol 6 (1) ◽  
pp. 13-26 ◽  
Author(s):  
G. Dorn

Summary1. A histochemical method has been applied to the detection of alkaline and acid phosphatase mutants in single colonies of Aspergillus nidulans.2. With the above method it has been possible to isolate mutants in which the alkaline and acid phosphatase activities are affected either separately or simultaneously.3. Crude extracts of wild-type A. nidulans contain four electrophoretically distinct phosphatase components, two with activity at alkaline pH and two with activity at acid pH. Genes affecting three of the four components have been identified.4. Two suppressor mutants of an alkaline phosphataseless mutant (palB7) have been isolated. In a strain carrying palB7 and one of these suppressors, the restoration of an alkaline phosphatase component is accompanied by loss of the faster acid phosphatase component. In a similar strain carrying the other suppressor, the partial restoration of the alkaline phosphatase component goes with an electrophoretic alteration of the slower acid phosphatase component.5. Genetic analysis of twenty-seven mutants has resulted in the identification of fifteen loci affecting the phosphatases. All these loci have been assigned to linkage groups, and twelve of them were also mapped meiotically in relation to other loci.6. One possible model (based on heteropolymeric proteins) has been proposed to account for the electrophoretic and genetic data on the various phosphatase and suppressor mutations.


MedChemComm ◽  
2012 ◽  
Vol 3 (8) ◽  
pp. 997 ◽  
Author(s):  
James F. Sanchez ◽  
Ruth Entwistle ◽  
David Corcoran ◽  
Berl R. Oakley ◽  
Clay C. C. Wang

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