scholarly journals SOCIOECONOMIC STATUS AND MISSED CLINICAL APPOINTMENTS IN AGE-RELATED MACULAR DEGENERATION

2018 ◽  
Vol 2 (suppl_1) ◽  
pp. 500-501
Author(s):  
B Dougherty ◽  
S Cooley ◽  
R Deffler ◽  
F Davidorf
Keyword(s):  
Socioeconomic Status ◽  
Macular Degeneration ◽  
Age Related Macular Degeneration ◽  
Age Related

The pattern and gender disparity in global burden of age-related macular degeneration

2020 ◽  
pp. 112067212092725
Author(s):  
Xiling Lin ◽  
Lixia Lou ◽  
Qi Miao ◽  
Yijie Wang ◽  
Kai Jin ◽  
...  
Keyword(s):  
Socioeconomic Status ◽  
Macular Degeneration ◽  
Gender Disparity ◽  
Age Related Macular Degeneration ◽  
Global Burden ◽  
Gini Coefficients ◽  
Male Ratio ◽  
Age Related ◽  
Life Years ◽  
And Gender

Purpose: To explore the trend patterns and gender disparity in global burden of age-related macular degeneration (AMD) by year, age, and socioeconomic status using disability-adjusted life-years (DALYs) from Global Burden of Disease (GBD) study 2017. Methods: DALYs and impairment data caused by AMD were extracted from GBD Study 2017. World Bank income level (WBIL) and human development index (HDI) in 2017 were cited as indicators of socioeconomic status. The Gini coefficients and the concentration indexes were calculated to unveil trends in between-country inequality. The association between gender inequality and socioeconomic levels was analyzed by Pearson correlation. Results: Total age-standardized DALYs of AMD showed a slightly descending pattern in recent years. However, gender disparity has existed since 1990 for almost three decades, with female being more heavily impacted. This pattern became more obvious with aging and varied among different WHO and WBIL regions. Meanwhile, female subjects tended to have higher vision impairments. Gini coefficients of AMD burden increased from 0.423 to 0.448, while the ones of female-to-male ratio fluctuated around 0.11 between 1990 and 2017, with concentration indexes changing from 0.024 to −0.057 and 0.046 to 0.029 respectively. Female-minus-male difference ( r = 0.1721, p = 0.0195) and female-to-male ratio ( r = 0.2072, p = 0.0048) of age-standardized DALYs rates were positively related to HDI. Conclusions: Though global AMD health care is progressing, gender imbalance in disease burden of AMD distribution barely improved. Gender sensitive health policy should be emphasized for the increasing elder population and relieving the higher AMD burden of females.

scholarly journals Association of Sex with the Global Burden of Age-related Macular Degeneration

2020 ◽  
Author(s):  
Jing Wu ◽  
Jiayue Zhou ◽  
Xiajing Tang ◽  
Xiaoning Yu ◽  
Xingchao Shentu
Keyword(s):  
Socioeconomic Status ◽  
Linear Regression ◽  
Macular Degeneration ◽  
Human Development ◽  
Pearson Correlation ◽  
Age Related Macular Degeneration ◽  
Global Burden ◽  
Regression Analyses ◽  
Public Attention ◽  
Age Related

Abstract Background: Age-related macular degeneration (AMD) is the third leading cause of blindness and affects approximately 196 million people. This study aims to explore the association of sex with the global burden of AMD by year, age, and socioeconomic status using disability-adjusted life-years (DALYs).Methods: Global, national sex-specific DALY numbers, crude DALY rates, and age-standardized DALY rates caused by AMD, by year and age, were extracted from the Global Burden of Disease Study 2017. The human development index (HDI) in 2017 was extracted as an indicator of national socioeconomic status from the Human Development Report 2018 (HDR 2018). Pearson correlation and linear regression analyses were conducted to investigate the association between socioeconomic status and sex inequality of AMD.Results: Differences in the sex-specific global burden of AMD have persisted since 1990 to 2017. Female individuals had higher burden than male individuals of the same age in 2017, and the differences gradually increased after 55 years and maximized at 80 years or older with 105.41 DALYs rates in female vs 81.00 DALYs rates in male. The paired Wilcoxon signed rank test indicated that female had higher age-standardized DALY rates than male had (Z = -6.520, P < 0.001) and countries with lower HDI values had higher age-standardized DALY rates among both sexes. DALY rate ratio and sex differences in age-standardized DALY rates were positively associated with HDI in both Pearson correlation analyses and linear regression analyses of AMD. (P < 0.05).Conclusions: Although global blindness and vision impairment health care is progressing, sex inequality in AMD burden remained persistent since the past few decades. These findings might raise more public attention to the gender differences in global AMD burden and the association between the sex-related global burden and socioeconomic status.

scholarly journals Socioeconomic status and visual outcome in patients with neovascular age-related macular degeneration

2020 ◽  
pp. 112067212092078
Author(s):  
Nadav Levinger ◽  
Gala Beykin ◽  
Michelle Grunin ◽  
Diego Almeida ◽  
Jaime Levy ◽  
...  
Keyword(s):  
Socioeconomic Status ◽  
Optical Coherence Tomography ◽  
Visual Acuity ◽  
Macular Degeneration ◽  
Medical Information ◽  
Visual Outcome ◽  
Age Related Macular Degeneration ◽  
Optical Coherence ◽  
Age Related ◽  
Baseline Visual Acuity

Purpose Visual outcome in patients with neovascular age-related macular degeneration is variable. We aimed to evaluate for association between socioeconomic status visual acuity in neovascular age-related macular degeneration. Methods A retrospective single-center study of a consecutive group of neovascular age-related macular degeneration patients was performed. Socioeconomic status was determined for each patient based on the 2008 Israeli census. Medical information was extracted from medical records and included visual acuity and optical coherence tomography parameters. Associations between socioeconomic status and clinical outcomes were analyzed. Results A total of 233 patients were included in the analysis. A correlation was found between low baseline visual acuity of the first eye diagnosed with neovascular age-related macular degeneration and low socioeconomic status (r = −0.13, p = 0.049; n = 233). The difference between the visual acuity of the lowest and the highest socioeconomic status categories at baseline was approximately 3 ETDRS lines (p = 0.048). Socioeconomic status and baseline visual acuity of the second eye of the same individual with neovascular age-related macular degeneration were not correlated (r = −0.05, p = 0.95). Socioeconomic status was not associated with the number of anti-vascular endothelial growth factor injections of the first or second eye, or the visual acuity outcome of the first or second eye after 1 year of therapy (p = 0.421, p = 0.9, respectively). Central subfield thickness of the first eye at presentation as measured by spectral-domain optical coherence tomography was associated with socioeconomic status (r = −0.31 p = 0.001). Conclusion Individuals of lower socioeconomic status presented at more advanced stage of the disease when developing neovascular age-related macular degeneration in the first eye but not in the second eye. The research underscores the importance of improving referral patterns and awareness for the lowest socioeconomic status classes.

Age related macular degeneration (ARMD) – pathophysiological and clinical features and therapeutic concepts

2001 ◽  
Vol 58 (1) ◽  
pp. 28-35 ◽  
Author(s):  
Ursula Körner-Stiefbold
Keyword(s):  
Macular Degeneration ◽  
Clinical Features ◽  
Altersbedingte Makuladegeneration ◽  
Age Related Macular Degeneration ◽  
Genetische Faktoren ◽  
Age Related ◽  
Therapeutic Concepts

Die altersbedingte Makuladegeneration (AMD) ist eine der häufigsten Ursachen für einen irreversiblen Visusverlust bei Patienten über 65 Jahre. Nahezu 30% der über 75-Jährigen sind von einer AMD betroffen. Trotz neuer Erkenntnisse in der Grundlagenforschung ist die Ätiologie, zu der auch genetische Faktoren gehören, noch nicht völlig geklärt. Aus diesem Grund sind die Behandlungsmöglichkeiten zum jetzigen Zeitpunkt noch limitiert, so dass man lediglich von Therapieansätzen sprechen kann. Die derzeit zur Verfügung stehenden Möglichkeiten wie medikamentöse, chirurgische und laser- und strahlentherapeutische Maßnahmen werden beschrieben.

Nutrition in Age-Related Macular Degeneration Survey

2018 ◽  
Author(s):  
Rebekah Stevens ◽  
Richard Cooke ◽  
Hannah Bartlett
Keyword(s):  
Macular Degeneration ◽  
Age Related Macular Degeneration ◽  
Age Related
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