scholarly journals Association between BMI and semen quality: an observational study of 3966 sperm donors

2018 ◽  
Vol 34 (1) ◽  
pp. 155-162 ◽  
Author(s):  
Jixuan Ma ◽  
Li Wu ◽  
Yun Zhou ◽  
Hai Zhang ◽  
Chengliang Xiong ◽  
...  
Keyword(s):  
Observational Study ◽  
Semen Quality ◽  
Sperm Count ◽  
Sperm Concentration ◽  
Normal Weight ◽  
Motile Sperm ◽  
Sperm Number ◽  
Sperm Donors ◽  
Semen Volume ◽  
Total Motile Sperm Count

Abstract STUDY QUESTION What is the relationship between abnormal BMI and semen quality? SUMMARY ANSWER Underweight was significantly associated with lower sperm concentration, total sperm number and total motile sperm count, while overweight was significantly associated with lower semen volume, total sperm number and total motile sperm count. WHAT IS KNOWN ALREADY Abnormal BMI has been associated with lower semen quality, but the results remain somewhat controversial. In addition, most previous studies have focused on the influence of obesity or overweight on semen quality, and evidence on the association between underweight and semen quality is rare. STUDY DESIGN, SIZE, DURATION This research was an observational study investigating 3966 sperm donors from a large sperm bank in Wuhan city, China. These donors passed the screening for sperm donation and underwent 29 949 semen examinations between 1 January 2013 and 9 April 2018. PARTICIPANTS/MATERIALS, SETTING, METHODS BMI was categorized into four groups: underweight (<18.5 kg/m2), normal weight (18.5–24.9 kg/m2), overweight (25–29.9 kg/m2) and obese (≥30 kg/m2). Semen volume, sperm concentration, total sperm number, total motility, progressive motility and total motile sperm count were determined by trained clinical technicians. Linear mixed models were used to conduct dose–response analyses between BMI and semen quality parameters. MAIN RESULTS AND THE ROLE OF CHANCE Underweight was significantly associated with a 3.0% (95% CI: 0.1%, 5.8%), 6.7% (1.9%, 11.3%) and 7.4% (2.2%, 12.4%) reduction in sperm concentration, total sperm number and total motile sperm count, respectively. Overweight was significantly associated with a 4.2% (1.6%, 6.8%), 3.9% (0.9%, 6.9%) and 3.6% (0.2%, 6.9%) reduction in semen volume, total sperm number and total motile sperm count, respectively. Non-linear models including continuous BMI as a natural cubic spline function yielded similar results. LIMITATIONS, REASONS FOR CAUTION Our study subjects were sperm donors who are typically young and healthy, and therefore not representative of the general male population. Caution should be paid in generalizing our results to other populations. Furthermore, we did not measure the donors’ weight repeatedly along with each semen donation; instead, we only measured it once during the screening, which may cause bias due to the variations of weight across time. WIDER IMPLICATIONS OF THE FINDINGS Our study provides evidence that underweight and overweight are associated with lower semen quality, and highlights the importance of maintaining a normal weight for men. STUDY FUNDING/COMPETING INTEREST(S) This work was supported by the Health and Family Planning Commission of Hubei Province (Grant number WJ2015MA027), the Hubei Provincial Committee of the Communist Youth League of China, and Center for Global and Regional Environmental Research at the University of Iowa. The authors declare that there are no conflicts of interest. TRIAL REGISTRATION NUMBER N/A.

Decline in semen quality among infertile men during the past 15 years in Western Algeria (SIDI-BEL-ABBES)

2016 ◽  
Vol 6 (4) ◽  
pp. 112-118
Author(s):  
El-haina Fatima Zohra ◽  
Bendahmane Malika
Keyword(s):  
Semen Quality ◽  
Sperm Count ◽  
Linear Regression Analysis ◽  
Semen Parameters ◽  
Motile Sperm ◽  
Infertile Men ◽  
Semen Volume ◽  
Western Algeria ◽  
Study Population ◽  
Total Motile Sperm Count

The current study aimed at measuring changes in semen quality and quantity in young healthy sperm of the partner in western Algeria over 15 years. A retrospective analysis of semen parameters over 15 years was carried out using linear regression analysis, at the fertility laboratory in West Algeria. Study population consisted of 188 young partners, aged 25 to 35 years, who donated sperm samples for artificial insemination between 2000 and 2015. Their wives with infertility problems were surveyed using questionnaire about their lifestyles and infertility factors. There were no statistically significant changes in semen concentration and motility during the study period. The mean semen volume increased by 0.1 mL per year (P < 0.0001), with a concomitant mean rise of 5.8 × 106 per year in total motile sperm count. The percentage of sperm normal morphology decreased by a mean of 1% per year during the entire period (P < 0.0001). During these 15 past years, there has been an increase in total motile sperm count, and semen volume where-as, a decline in normal sperm morphology has been noticed that is independ-ent of the age and the duration of abstinence of infertile men.

scholarly journals The Association Between Abstinence Period and Semen Parameters: Results in Normal Samples and Different Sperm Pathology

2021 ◽  
Author(s):  
Min Xie ◽  
Silvan Hämmerli ◽  
Kerstin Blickenstorfer ◽  
Brigitte Leeners
Keyword(s):  
Semen Quality ◽  
Sperm Quality ◽  
Sperm Count ◽  
Sperm Concentration ◽  
Semen Parameters ◽  
Sexual Abstinence ◽  
Normal Morphology ◽  
Few Data ◽  
Total Motile Sperm Count ◽  
Abstinence Period

Abstract Purpose: The length of sexual abstinence seems to influence sperm quality. However, few data on the relevance of abstinence time in pathological sperm samples are available. With our study, we look for associations of abstinence length and semen quality. Methods: We studied semen samples from 4423 men undergoing fertility evaluation. Sperm concentration, percentage of progressively motile spermatozoa, total motile sperm count, percentage of spermatozoa with normal morphology, were compared after each day and 0-2, 3-7 and >7 days of abstinence. Results: We found that a longer abstinence time was related to higher sperm concentration in normal semen samples (P<0.001) and in semen samples with any sperm pathology (P<0.001, P=0.004) with the exception of oligozoospermia (P=0.125). Longer abstinence time was also associated with significantly reduced progressive motility in normal samples (P<0.001) and in cases of teratozoospermia (P<0.001). In normal samples a higher percentage of sperm were morphologically normal after a shorter abstinence period (P=0.03); in oligoasthenoteratozoospermia (OAT) samples, this was the case after a longer abstinence period (P=0.013). Conclusion: A longer abstinence time is associated with higher sperm concentration, whereas sperm motility is optimal after shorter abstinence times; results on morphology are controversial. The recommendation on abstinence time needs to be adjusted in relation to the parameter that needs to be improved.

scholarly journals Analysis of seasonal variability of sperm donors’ semen parameters

2018 ◽  
Vol 8 (3) ◽  
pp. 28-35
Author(s):  
Igor A. Korneyev ◽  
Ruslan D. Zasseev ◽  
Ol'ga B. Pashina ◽  
Ali E. Mamedov ◽  
Al'bert M. Dogov ◽  
...  
Keyword(s):  
Seasonal Variability ◽  
Reproductive Medicine ◽  
Sperm Concentration ◽  
Sperm Parameters ◽  
Semen Parameters ◽  
Motile Sperm ◽  
Sperm Number ◽  
Progressive Motility ◽  
Sperm Donors ◽  
The Mean

Introduction. The concept of seasonal variability of sperm parameters is controversial. However, it should be considered during medical evaluation and solicitation of sperm donors. Aim. To evaluate seasonal variability of sperm parameters from anonymous sperm donors in a reproductive medicine center. Materials and methods. A retrospective study of 1252 semen samples from 39 sperm donors (mean age 27.1 ± 3.9 years) in a reproductive medicine center in Saint Petersburg during the period from October 1, 2015 to October 1, 2017 was performed according to WHO 2010 recommendations. Semen volume, sperm concentration, total sperm number, progressive motility, and number of progressively motile sperm were analyzed. Results. Individual variability in semen parameters was high. The mean ejaculate volume in the summer months was higher than in the autumn, winter, and spring (t = 3.65, p < 0.001; t = 4.18, p < 0.0001; t = 1.92, p = 0.056 respectively). The lowest volume (2.83 ± 1.32 ml) was registered in January. The mean sperm concentration in summer was lower than in autumn, winter, and spring (t = 3.65, p < 0.001; t = 4.18, p < 0.0001; t = 1.92, p = 0.056 respectively). It was higher in winter than in spring and autumn (t = 2.54, p = 0.012; t = 1.72, p = 0.082 respectively). The highest mean sperm concentration was registered in January and the lowest in July (157.2 ± 46.6 and 131.9 ± 44.0 million sperm per ml, respectively). No significant seasonal differences were found in total sperm number, progressive motility, or number of progressively motile sperm (p > 0.1). Conclusions. The study suggests there is both individual and seasonal variability in sperm donors’ semen parameters. As several semen samples are needed to rate semen quality, we recommend that semen analysis for a potential sperm donor be performed in the summer months.

scholarly journals MP26-14 EXTERNAL VALIDATION OF THE POST-VARICOCELECTOMY SEMEN QUALITY NOMOGRAM TO PREDICT TOTAL MOTILE SPERM COUNT

2020 ◽  
Vol 203 ◽  
pp. e405-e406
Author(s):  
Hyung Ho Lee ◽  
Won Sik Jang ◽  
Ji Eun Heo ◽  
Jong Soo Lee ◽  
Ki Hong Kim ◽  
...  
Keyword(s):  
Semen Quality ◽  
Sperm Count ◽  
External Validation ◽  
Motile Sperm ◽  
Total Motile Sperm Count

scholarly journals Semen parameter improvements after microsurgical subinguinal varicocele repair are durable for more than 12 months

2019 ◽  
Vol 14 (3) ◽  
Author(s):  
Vinayak Madhusoodanan ◽  
Premal Patel ◽  
Ruben Blachman-Braun ◽  
Ranjith Ramasamy
Keyword(s):  
Semen Quality ◽  
Sperm Count ◽  
Semen Parameters ◽  
Semen Parameter ◽  
Semen Volume ◽  
Retrospective Nature ◽  
Baseline Characteristics ◽  
One Year ◽  
Varicocele Repair ◽  
Total Motile Sperm Count

Introduction: Varicoceles account for the most common correctable cause of male infertility, with varicocele repair leading to improvements in semen quality. However, there is little evidence to establish the durability of varicocele repair. We analyzed the durability of improvements in postoperative semen parameters following microsurgical subinguinal varicocele repair. Methods: We evaluated all men who underwent microscopic subinguinal varicocelectomy from 2015‒2019. Patients were included if they desired fertility and had a followup of at least 12 months. We assessed the baseline characteristics of these patients, as well as semen volume, total motile sperm count (TMSC), concentration, percent motility, and morphology. Semen parameters were analyzed at baseline (preoperative), approximately three months and ≥12 months postoperatively. Results: Of 105 men who underwent varicocelectomy, 18 men had a followup of at least 12 months. These men presented with median age 34.5 (27–38] years for a median followup duration of 14.5 (13–22.5) months. TMSC levels increased from 6.4 (1.1–24.5) million at baseline to 11.1 (2.4–38.4) million at approximately three months and remained similar at 12.5 (1.6–31.5) million at ≥12 months. The study is limited by its retrospective nature and limited sample size. Conclusions: Microscopic subinguinal varicocele repairs can result in durable improvements of semen quality beyond one year, as demonstrated by upgrade in median TMSC. Further studies should be performed to confirm our findings.

scholarly journals ASSOCIATIONS BETWEEN PITUITARY-GONADAL AXIS PARAMETERS AND SEMEN QUALITY IN YOUNG, HEALTHY MEN (AndroLS)

2019 ◽  
Vol 15 (3) ◽  
pp. e11-e24
Author(s):  
Józków Paweł ◽  
Medras Marek ◽  
Szmigiero Leszek ◽  
Słowinska-Lisowska Małgorzata ◽  
Lwow Felicja
Keyword(s):  
Sperm Morphology ◽  
Semen Quality ◽  
Sperm Count ◽  
Sperm Concentration ◽  
Free Testosterone ◽  
Quality Parameters ◽  
Sex Hormone Binding Globulin ◽  
Total Testosterone ◽  
Semen Volume ◽  
The Impact

Background and ObjectiveHormonal measurements play an important role in the evaluation of male fertility potential. In men without hypogonadism, the impact of androgen status on semen is rarely analyzed.Material and MethodsWe evaluated associations between parameters of the pituitary-gonadal axis: luteinizing hormone (LH), follicle-stimulating hormone (FSH), total testosterone (T), free testosterone (FT), calculated testosterone (TC), bioavailable testosterone (TB), sex hormone-binding globulin (SHBG), free androgen index, and semen quality parameters in healthy young men.ResultsIn our study group, sperm concentration and sperm count were associated with FSH and FT. The percentage of immotile sperm was associated with LH and T. The percentage of vital sperm was negatively related to LH. We identified negative, independent associations between T and semen volume (p<0.026) and TC and semen volume (p<0.025). We observed negative, independent association between FSH, FT, and total sperm count (both P<0.002) and between FT and the percentage of normal forms (P<0.012). There were positive associations between LH and T and the percentage of immotile sperm (P<0.007 and P<0.034, respectively). There were no relationships between sperm morphology parameters and the parameters of the pituitary-gonadal axis.ConclusionIn healthy eugonadal men, variations in FSH, LH, T, and FT (within normal limits) are reflected in semen characteristics but not in sperm morphology features.

scholarly journals The Association Between Abstinence Period And Semen Parameters: Results In Normal Samples And Different Sperm Pathology

2021 ◽  
Author(s):  
Min Xie ◽  
Silvan Haemmerli ◽  
Kerstin Blickenstorfer ◽  
Brigitte Leeners
Keyword(s):  
Semen Quality ◽  
Sperm Quality ◽  
Sperm Count ◽  
Sperm Concentration ◽  
Semen Parameters ◽  
Sexual Abstinence ◽  
Normal Morphology ◽  
Few Data ◽  
Total Motile Sperm Count ◽  
Abstinence Period

Abstract Purpose: The length of sexual abstinence seems to influence sperm quality. However, few data on the relevance of abstinence time in pathological sperm samples are available. With our study, we look for associations of abstinence length and semen quality. Methods: We studied semen samples from 4423 men undergoing fertility evaluation. Sperm concentration, percentage of progressively motile spermatozoa, total motile sperm count, percentage of spermatozoa with normal morphology, were compared after each day and 0-2, 3-7 and >7 days of abstinence.Results: We found that a longer abstinence time was related to higher sperm concentration in normal semen samples (P<0.001) and in semen samples with any sperm pathology (P<0.001, P=0.004) with the exception of oligozoospermia (P=0.125). Longer abstinence time was also associated with significantly reduced progressive motility in normal samples (P<0.001) and in cases of teratozoospermia (P<0.001). In normal samples a higher percentage of sperm were morphologically normal after a shorter abstinence period (P=0.03); in oligoasthenoteratozoospermia (OAT) samples, this was the case after a longer abstinence period (P=0.013).Conclusion: A longer abstinence time is associated with higher sperm concentration, whereas sperm motility is optimal after shorter abstinence times; results on morphology are controversial. The recommendation on abstinence time needs to be adjusted in relation to the parameter that needs to be improved.

scholarly journals Antioxidant Vitamins and Carotenoids Intake and the Association With Poor Semen Quality: A Cross-Sectional Analysis of Men Referring to an Italian Fertility Clinic

2021 ◽  
Vol 8 ◽  
Author(s):  
Valentina De Cosmi ◽  
Fabio Parazzini ◽  
Carlo Agostoni ◽  
Stefania Noli ◽  
Sonia Cipriani ◽  
...  
Keyword(s):  
Randomized Clinical Trials ◽  
Semen Quality ◽  
Sperm Count ◽  
Sperm Concentration ◽  
Cross Sectional ◽  
Cross Sectional Analysis ◽  
Health History ◽  
Semen Volume ◽  
Sectional Analysis ◽  
Β Carotene

Several studies suggested that male's diet affects fertility. This cross-sectional analysis from a prospective cohort study aims to explore the relation between antioxidants intake and sperm parameters in sub-fertile couples referring to a Fertility center. Socio-demographic characteristics, health history, lifestyle habits, and diet information were obtained. A semen sample was analyzed to proceed with assisted reproduction. Three hundred and twenty-three men were enrolled: 19.1% had semen volume (SV) &lt; 1.5 mL, 31.4% sperm concentration (SC) &lt; 15.0 mil/mL, 26.8% sperm motility &lt; 32%, and 33.0% had total sperm count (TSC) &lt; 39.0 mil. Higher levels of α-carotene were associated to lower risk of low SC [4th vs. 1st quartile, adjusted OR (aOR) 0.43, 95% CI 0.20–0.91) and low TSC (aOR 0.46, 95% CI 0.22–0.95). Higher intake of β-carotene was inversely associated with risk of low TSC. Lycopene intake was associated with higher risk for these conditions (aOR 2.46, 95%CI 1.01–5.98, SC), and (aOR 3.11, 95%CI 1.29–7.50, TSC). Risk of low semen volume was lower in men with higher level of vitamin D intake (aOR 0.25, 95%CI 0.09–0.66)]. Further research, especially, well-designed randomized clinical trials (RCT), is needed to understand how diet modifications may have a role in modulating male fertility and fecundability.

Analysis of diurnal variability of sperm donors’ semen parameters

2019 ◽  
Vol 9 (1) ◽  
pp. 11-16
Author(s):  
Igor A. Korneyev ◽  
Ruslan D. Zasseev ◽  
Ol’ga B. Pashina ◽  
Ali E. Mamedov ◽  
Pavel S. Kondrashkin ◽  
...  
Keyword(s):  
Reproductive Medicine ◽  
Semen Analysis ◽  
Sperm Concentration ◽  
Sperm Parameters ◽  
Semen Parameters ◽  
Motile Sperm ◽  
Diurnal Variability ◽  
Sperm Donors ◽  
Medical Evaluation ◽  
Semen Volume

Introduction. Diurnal variability of sperm parameters is controversial and should be considered during medical evaluation and solicitation of sperm donors. Aim: to evaluate diurnal variability of sperm parameters of anonymous sperm donors in reproductive medicine center. Materials and methods. Records of 1253 semen samples analysis of 39 sperm donors (mean age 27.1 ± 3.9 years) were retrospectively studied in reproductive medicine center in Saint Petersburg. Semen analysis was performed according to WHO 2010 recommendations. Diurnal variations of semen volume, sperm concentration, total sperm number, progressive motility and number of progressively motile sperm were analyzed. Results. Mean ejaculate volume, sperm total number and number of progressively motile sperm were higher after 3 p.m. (t = 5.63, p < 0.0001; t = 3.66, p = 0.0003 and t = 1.76, p = 0.078, respectively), while sperm concentration and percent of progressively motile sperm was lower (t = 2.03, p = 0.043 and t = 4.63, p = 0.0003, respectively).The lowest and the highest mean sperm numbers were registered in time slots between 12 a.m.–1 p.m. and 4 p.m.–5 p.m., respectively. Conclusions. The study suggests the diurnal variability of sperm donors’ semen parameters. We might recommend a potential sperm donor preservation to be performed after 3 p.m., preferentially within 4 p.m.–5 p.m. interval.

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