Prevalence of Hepatitis B Virus Infection in Tonga: Identifying High Risk Groups for Immunization with Hepatitis B Vaccine

1986 ◽  
Vol 15 (4) ◽  
pp. 567-571 ◽  
Author(s):  
ROBERT B WAINWRIGHT ◽  
BRIAN J MCMAHON ◽  
THOMAS R BENDER ◽  
WILLIAM L HEYWARD ◽  
STEVEN NAKANISHI ◽  
...  
Keyword(s):  
Hepatitis B Virus ◽  
High Risk ◽  
Virus Infection ◽  
Hepatitis B ◽  
Risk Groups ◽  
Hepatitis B Vaccine ◽  
Hepatitis B Virus Infection ◽  
B Virus

scholarly journals Heterosexual Transmission of Hepatitis B and Implications for Vaccine Prevention Strategies

1991 ◽  
Vol 2 (suppl a) ◽  
pp. 13-17 ◽  
Author(s):  
Miriam J Alter
Keyword(s):  
United States ◽  
Hepatitis B Virus ◽  
High Risk ◽  
Virus Infection ◽  
Hepatitis B ◽  
Risk Groups ◽  
The United States ◽  
Hepatitis B Virus Infection ◽  
B Virus ◽  
Homosexual Activity

Since 1985, cases of hepatitis B virus infection attributable to heterosexual activity have increased by 38%, whereas those attributable to homosexual activity have declined by 62%, Heterosexual activity now accounts for 26% of cases and has replaced homosexual activity in importance as a risk factor for hepatitis B. For heterosexuals, the number of recent (ie, in the preceding four to six months) and lifetime sex partners, as well as a history of other sexually transmitted diseases (eg. syphilis) appear to be significantly associated with increased hepatitis B virus infection. Of equal concern is the rising number of cases among parenteral drug users in the United States and some minority groups, including blacks, Hispanics and Asians. Hepatitis B prevention by administering hepatitis B vaccine to high risk groups before exposure to infection has not been successful, and at least 30% of hepatitis B cases in the United States have no identifiable risk factors. Thus, participation in the current programs which target only high risk groups is not possible. The ideal immunization strategy is integration of hepatitis B vaccine in to the routine childhood immunization schedule.

scholarly journals Seroconversion after Recombinant Hepatitis B Vaccination

1970 ◽  
Vol 11 (2) ◽  
pp. 143-150 ◽  
Author(s):  
Abhijit Guho ◽  
Md Abdul Ahad ◽  
Md Abdus Salam ◽  
Md Abdul Alim ◽  
AKM Enamul Haque ◽  
...  
Keyword(s):  
Hepatitis B Virus ◽  
Virus Infection ◽  
Hepatitis B ◽  
Hepatitis B Vaccine ◽  
Hepatitis B Virus Infection ◽  
Recombinant Hepatitis ◽  
Protective Level ◽  
Significant Difference ◽  
B Virus ◽  
Study Population

Background: Hepatitis B virus infection is an important public health problem with significant morbidity andmortality. Recombinant hepatitis B vaccine for the prevention of hepatitis B virus infection is in practice in differentparts of the world since its availability in 1986. Government of Bangladesh has also included hepatitis B vaccine inEPI schedule since 2005.Materials and methods: This study was carried out to assess the seroconversion status among hepatitis Bvaccinated individuals. A total of 190 individuals including 150 vaccinated persons and 40 non-vaccinated apparentlyhealthy individuals were included as study population. Sources of vaccinated persons were from both EPI and non-EPI schedule of vaccination. Age and sex matched non-vaccinated individuals served as controls for the study. Allindividuals constituting the study population were screened for HBsAg by Immunochromatographic strip test andonly HBsAg-negative persons were included for estimation of their anti-HBs titer.Results: Out of 150 vaccinated individuals, 133(88.67%) were found to have anti-HBs titer in the protective level(>10 IU/L), while 17(11.33%) individuals had anti-HBs titer below the protective level (<10 IU/L). All non-vaccinatedcontrols had anti-HBs titers below the protective level. Regarding immune response developed among vaccinatedindividuals, 67.78%, 23.33% and 8.89% were good-responders, hypo-responders and non-responders respectively.Mean titer of anti-HBs was found significantly higher among recipients who received booster dose than those whoreceived 3 doses schedule (863.39 IU/L vs. 262.40 IU/L), indicating high antibody titer develops after booster dose.Vaccinated group included 85 (56.67%) men and 65 (43.33%) women with protective level of anti-HBs titer foundin 85.88% male and 92.31% female individuals. There was no significant difference of anti-HBs titer between maleand female (p>0.05). Vaccinated individuals from lower socioeconomic condition have had comparatively low rateof protective antibody than people from middle and upper classes.Conclusion: Recombinant HB vaccine induces good level of protective immunity among vaccinated persons.Keywords: Hepatitis B; hepatitis B vaccine; seroconversion; BangladeshDOI: 10.3329/jom.v11i2.5461J MEDICINE 2010; 11 : 143-150

Hepatitis B virus infection in high-risk inner-city neighborhoods in San Francisco

Hepatology ◽  
1995 ◽  
Vol 22 (1) ◽  
pp. 44-49
Author(s):  
David Siegel ◽  
Miriam J. Alter ◽  
Stephen Morse
Keyword(s):  
Hepatitis B Virus ◽  
High Risk ◽  
Virus Infection ◽  
Hepatitis B ◽  
Inner City ◽  
San Francisco ◽  
Hepatitis B Virus Infection ◽  
B Virus

The efficacy of accelerated, multiple, double-dose hepatitis B vaccine against hepatitis B virus infection in cancer patients receiving chemotherapy

2015 ◽  
Vol 34 (5) ◽  
pp. 372-379 ◽  
Author(s):  
Jaswinder Singh Sodhi ◽  
Wasim Raja ◽  
Showkat Ali Zargar ◽  
Abid Showkat ◽  
Shaheena Parveen ◽  
...  
Keyword(s):  
Hepatitis B Virus ◽  
Virus Infection ◽  
Hepatitis B ◽  
Cancer Patients ◽  
Hepatitis B Vaccine ◽  
Hepatitis B Virus Infection ◽  
Double Dose ◽  
B Virus
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