scholarly journals Factors influencing caspofungin plasma concentrations in patients of a surgical intensive care unit

2007 ◽  
Vol 60 (1) ◽  
pp. 100-106 ◽  
Author(s):  
T. H. Nguyen ◽  
T. Hoppe-Tichy ◽  
H. K. Geiss ◽  
A. C. Rastall ◽  
S. Swoboda ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Plasma Concentrations ◽  
Surgical Intensive Care Unit ◽  
Surgical Intensive Care ◽  
Factors Influencing

scholarly journals Plasma Concentrations of Posaconazole Administered via Nasogastric Tube in Patients in a Surgical Intensive Care Unit

2012 ◽  
Vol 56 (8) ◽  
pp. 4468-4470 ◽  
Author(s):  
Dominic Störzinger ◽  
Stephan Borghorst ◽  
Stefan Hofer ◽  
Cornelius J. Busch ◽  
Christoph Lichtenstern ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Nasogastric Tube ◽  
High Performance ◽  
Plasma Concentrations ◽  
Volume Of Distribution ◽  
Surgical Intensive Care Unit ◽  
Surgical Intensive Care ◽  
Drug Concentrations ◽  
Apparent Clearance

ABSTRACTAbdominal surgery may affect intestinal absorption and the resulting levels of posaconazole in the blood. We measured plasma posaconazole levels in surgical intensive care unit (SICU) patients and tried to develop a predictive population pharmacokinetics model. A total of 270 samples from 15 patients receiving posaconazole via nasogastric tube were measured by high-performance liquid chromatography (HPLC). SICU patients showed lower plasma drug concentrations, a higher apparent clearance, and a higher volume of distribution than those in hematology patients, possibly due to poor absorption.

FACTORS INFLUENCING DO-NOT-RESUSCITATE (DNR) DECISION MAKING IN A SURGICAL INTENSIVE CARE UNIT

1999 ◽  
Vol 27 (Supplement) ◽  
pp. 172A
Author(s):  
Matthew D. Bacchetta ◽  
Lynn J. Hydo ◽  
Diane P. Heller ◽  
Soumitra R. Eachempati ◽  
Philip S. Barie
Keyword(s):  
Intensive Care Unit ◽  
Decision Making ◽  
Intensive Care ◽  
Surgical Intensive Care Unit ◽  
Do Not Resuscitate ◽  
Surgical Intensive Care ◽  
Factors Influencing
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