scholarly journals Characterization of poxtA, a novel phenicol–oxazolidinone–tetracycline resistance gene from an MRSA of clinical origin

2018 ◽  
Vol 73 (7) ◽  
pp. 1763-1769 ◽  
Author(s):  
Alberto Antonelli ◽  
Marco Maria D’Andrea ◽  
Andrea Brenciani ◽  
Cesira L Galeotti ◽  
Gianluca Morroni ◽  
...  
2000 ◽  
Vol 44 (3) ◽  
pp. 790-793 ◽  
Author(s):  
Claire Poyart ◽  
Gilles Quesne ◽  
Philippe Acar ◽  
Patrick Berche ◽  
Patrick Trieu-Cuot

ABSTRACT Clinical blood isolates from three sequential episodes of endocarditis occurring over a 6-month period in a child with a malformative cardiopathy were investigated. All isolates identified asAbiotrophia defectiva were resistant to erythromycin-clindamycin and to tetracycline-minocycline, due to the presence of sequences homologous to the erythromycin resistance geneermB and to the tetracycline resistance genetet(M), respectively. These resistance genes were located on a chromosomally borne composite Tn916-related transposon. These results demonstrate the involvement of conjugative transposons in the dissemination of antibiotic resistance in the genusAbiotrophia.


2003 ◽  
Vol 47 (4) ◽  
pp. 1430-1432 ◽  
Author(s):  
M. L. Diaz-Torres ◽  
R. McNab ◽  
D. A. Spratt ◽  
A. Villedieu ◽  
N. Hunt ◽  
...  

ABSTRACT A major drawback of most studies on how bacteria become resistant to antibiotics is that they concentrate mainly on bacteria that can be cultivated in the laboratory. In the present study, we cloned part of the oral metagenome and isolated a novel tetracycline resistance gene, tet(37), which inactivates tetracycline.


2000 ◽  
Vol 44 (3) ◽  
pp. 775-777 ◽  
Author(s):  
Karen P. Scott ◽  
Claire M. Melville ◽  
Teresa M. Barbosa ◽  
Harry J. Flint

ABSTRACT Members of our group recently identified a new tetracycline resistance gene, tet(W), in three genera of rumen obligate anaerobes. Here, we show that tet(W) is also present in bacteria isolated from human feces. The tet(W) genes found in human Fusobacterium prausnitzii andBifidobacterium longum isolates were more than 99.9% identical to those from a rumen isolate of Butyrivibrio fibrisolvens.


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