Analytical Methods for Foods in the Next Decade

1982 ◽  
Vol 65 (3) ◽  
pp. 531-534
Author(s):  
James T Tanner

Abstract With each passing decade new problems arise for the regulatory analytical chemist. The push for low detection limits from percent to parts per million to parts per billion brought the need for new and improved analytical instrumentation followed by questions of reliability at such low values. Each question has been met by new instruments or techniques and critical studies. The question for the 1980s is not how to achieve low detection limits but how to reliably and rapidly perform analyses at low values. During the 1960s the emphasis was on the single component/element techniques. We seem now to be entering the computer-controlled era. In each analytical specialty, computer-controlled instruments are offered which greatly aid the analyst in producing an accurate, reliable analysis in a shorter time. The advantage of larger numbers of analyses per unit of time with, in some cases, reduced personnel are not to be overlooked in this age of economy. To the AOAC collaborative study this means a reduction in the number of laboratories who can participate. It also means greater standardization of methodology, and the chemist’s laboratory ability becomes less of a factor in producing reliable analyses. Specific analytical examples are discussed to illustrate the trend for the 1980s.

1990 ◽  
Vol 36 (8) ◽  
pp. 1408-1427 ◽  
Author(s):  
James P Gosling

Abstract Immunoassays are now very widely used in the clinical laboratory, either because no other type of assay system is feasible or because they are often the most effective and suitable of the possible analytical methods. The last decade has seen the development and refinement of many new immunoassay reagents and systems. The major trend has been away from liquid-phase assays involving radioisotopic labels, towards fast homogeneous or solid-phase assays capable of operation anywhere; and towards precise and reliable nonisotopic, automated or semi-automated laboratory assays, often with detection limits measured in pico- or attomoles. The use of monoclonal antibodies is now widespread, and the methodologies of labels and of solid-phase components are much more sophisticated. New assay formulations, novel homogeneous systems, immunosensors, free-analyte assays, the importance of thorough validation and of interfering substances, and future trends are discussed.


2020 ◽  
pp. 95-100
Author(s):  
VILENA ANATOLYEVNA YAKIMOVA ◽  

The article presents the directions of development of the methodology of compliance control as one of the forms of control and audit activities of organizations. A system of expert-analytical methods and tools is proposed, a feature of which is the grouping of methods by types and functions of compliance control. In the course of the study, it was found that analytical indicators play the role of indicators indicating possible risks of violation of regulatory legal acts, and make it possible to quickly predict and assess the financial losses of an organization.


Fuel ◽  
1996 ◽  
Vol 75 (4) ◽  
pp. 424-430 ◽  
Author(s):  
Kevin Galbreath ◽  
Christopher Zygarlicke ◽  
Gary Casuccio ◽  
Tracy Moore ◽  
Paul Gottlieb ◽  
...  

1967 ◽  
Vol 50 (3) ◽  
pp. 526-530
Author(s):  
Robert K Johnson

Abstract A collaborative study of the method derived from one proposed by Schumacher, This Journal, 48, 819-826 (1965), was sponsored by the Subcommittee on Analytical Methods, Certified Color Industry Committee. All 6 domestic manufacturers of certified food colors were represented as well as the Division of Color Certification and Evaluation, FDA, Washington, D.C. Eight collaborators analyzed 3 samples each. Intermediates were separated by column chromatography and their concentrations were estimated from ultraviolet absorption measurements. N-Ethyl-iV-(3-sulfobenzyl) sulfanilic acid (ESBSA) and mixed isomers of sulfobenzaldehyde (SB) were recovered at an average level of 98% of the amounts added. Between-laboratory standard deviations ranged from 0.014 to 0.18% when the intermediates were present at levels of 0.07-1.46%. The method is recommended for adoption as official, first action


1998 ◽  
Vol 81 (5) ◽  
pp. 978-990 ◽  
Author(s):  
Gertraud Suhren ◽  
Robert Beukers

Abstract Under the auspices of the International Dairy Federation's Group E503, a collaborative study of the Delvotest SP multiplate microbial inhibitor test was performed to gain information about the detection limits of 2 antimicrobial agents (a β-lactam and a sulfa compound), the variation of test results between users and 2 batches of the test, and the reasons for deviating results. Lyophilized milk samples spiked with various concentrations of cloxacillin or sulfamethoxazole were analyzed. Each substance/concentration combination was tested with each of 2 test batches 14 or 15 times per participating laboratory. Test results were to be read by more than one person and reported on separate forms. Results were obtained from 29 laboratories, which included 5 with no experience and 11 with limited experience with this test. Detection limits for cloxacillin (22.5 or 30 μg/kg, depending on batch) and sulfamethoxazole (45 μg/kg) were established from dose-response curves. A small difference in cloxacillin detection levels between the 2 test batches was observed. Analyses of samples gave almost unanimous results (≥95%). Of deviating results, defined as anomalous results (1.4% of readings), half could be attributed to human errors and half to procedural errors


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