Determination of Semduramicin Sodium in Poultry Liver by Liquid Chromatography with Vanillin Postcolumn Derivatization
1994 ◽
Vol 77
(3)
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pp. 577-582
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Keyword(s):
The Mean
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Abstract A liquid chromatographic (LC) method is described for the quantitative determination of semduramicin sodium in broiler liver when administered under projected use conditions. For this procedure, semduramicin sodium is extracted from liver with methanolic ammonium hydroxide, separated and concentrated by solid-phase extraction steps, and determined by LC with postcolumn derivatization with vanillin. The mean recovery of drug was 95% over the 40-320 ng/g range, the coefficient of variation was ±10% or better, and no interference was observed from commercial poly ether ionophores. The minimum level of detection for semduramicin sodium in broiler liver is 25 ng/g.
2009 ◽
Vol 1216
(27)
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pp. 5176-5181
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2008 ◽
Vol 617
(1-2)
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pp. 216-224
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1992 ◽
Vol 75
(5)
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pp. 790-795
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2005 ◽
Vol 53
(11)
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pp. 1472-1474
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2007 ◽
Vol 858
(1-2)
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pp. 168-176
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2005 ◽
Vol 20
(2)
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pp. 275-283
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1988 ◽
Vol 71
(4)
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pp. 776-778
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