scholarly journals 260 Effects of iron administration timing on pre-weaning performance and hematological criteria in pigs

2020 ◽  
Vol 98 (Supplement_3) ◽  
pp. 88-89
Author(s):  
Hayden E Williams ◽  
Ryan T Maurer ◽  
Brittany Carrender ◽  
Joel M DeRouchey ◽  
Jason C Woodworth ◽  
...  

Abstract Newborn pigs (n=1,892; 1.5 kg BW) were used in a 20-d study evaluating the effects of Fe injection timing after birth on preweaned pig performance and blood criteria. A total of 172 litters were used. One d after farrowing, piglets were weighed, and 11 pigs within each litter were allotted to 1 of 6 treatments in a CRD. Treatments consisted of pigs receiving no Fe injection or 200-mg of injectable Fe (GleptoForte, Ceva Animal Health, Lenexa, KS) provided on d 1, 3, 5, or 7 of age, or 200-mg on d 1 plus 200-mg on d 12. 1 pig/litter received no Fe injection and 2 pigs/litter were placed on all other treatments. Piglets were weighed on d 1 and 20 after birth to determine growth performance and bled on d 20 to determine Fe status. Increasing the age that piglets received the Fe injection tended to decrease (linear; P=0.080) ADG. Not providing an Fe injection decreased (P=0.0001) overall ADG and d 20 BW compared to all other treatments. Hemoglobin and Hct decreased (linear; P< 0.05) with increasing age when pigs received an Fe injection. There was no evidence of differences (P >0.10) between the pigs receiving a 200-mg injection on d 1 and d 12 compared to those receiving the Fe on d 1 only. Pigs not provided an Fe injection had decreased (P=0.0001) Hb and Hct values compared to pigs receiving an Fe injection. Pigs receiving the 200-mg injection on d 1 and 12 had increased (P=0.0001) Hb and Hct values compared to pigs receiving 200-mg on d 1 only. Results suggest that providing a 200-mg Fe injection within 7 d after farrowing is sufficient for optimizing preweaning growth performance. The additional 200-mg Fe injection at d 12 did not influence growth performance but does increase Hb and Hct at weaning.

2019 ◽  
Vol 97 (Supplement_2) ◽  
pp. 151-152
Author(s):  
Cierra Roubicek ◽  
Hayden E Williams ◽  
Joel M DeRouchey ◽  
Jason C Woodworth ◽  
Steve S Dritz ◽  
...  

Abstract Newborn pigs (n = 324; 1.6 kg BW) were used in an 19-d study evaluating the effects of Fe injection timing after birth on preweaned pig performance and blood criteria. A total of 27 litters were used, with the number of pigs per sow equalized on each day of farrowing. Two d after farrowing, all piglets were weighed, and six barrows and six gilts within each litter were allotted to 1 of 6 treatments in a CRD. Treatments consisted of a negative control receiving no Fe injection or 200 mg of injectable Fe (Gleptoforte, Ceva Animal Health, Lenexa, KS) provided on d 2, 4, 6, 8, or 10 after farrowing. Piglets were weighed and bled on d 2, 12, and 21 after birth to determine growth performance and blood Fe status. Overall, increasing the age that piglets received a 200 mg Fe injection until 4 or 6 d after birth tended to increase (quadratic; P = 0.065) ADG (Table 1). Not providing an Fe injection tended to decrease (P = 0.070) overall ADG and decreased (P = 0.0003) d 21 BW compared to all other treatments. Significant treatment×day interactions (P < 0.001) were observed for hemoglobin (Hgb) and hematocrit (Hct). The interactions occurred because pigs injected with 200 mg of Fe on d 2, 4, 6, or 8 after birth had increasing values until d 21 after birth, while pigs receiving a 200 mg Fe injection on d 10 after birth had decreasing values to d 12 then increasing values to d 21. Pigs not provided an Fe injection after birth had decreasing values to d 21. These results suggest that providing a 200 mg Fe injection on d 4 or 6 after farrowing provided the greatest preweaning growth performance and blood Fe status until weaning.


Author(s):  
Hayden E Williams ◽  
Brittany Carrender ◽  
Cierra D Roubicek ◽  
Ryan Maurer ◽  
Joel M DeRouchey ◽  
...  

Abstract Two experiments were conducted to evaluate the effects of Fe injection timing after birth on suckling and subsequent nursery and growing-finishing pig performance. The injectable Fe source used in both experiments was GleptoForte (Ceva Animal Health, LLC., Lenexa, KS). GleptoForte contains gleptoferron which is a Fe macro-molecule complex. In Exp. 1, a total of 324 newborn pigs [DNA 241 × 600, initially 1.6 ± 0.04 kg body weight (BW)] within 27 litters were used. Two days after birth, all piglets were weighed, and six barrows and six gilts per litter were allotted to 1 of 6 treatments consisting of no Fe injection or 200 mg of injectable Fe provided in a single injection on d 2, 4, 6, 8, or 10 of age. Pigs were weaned (~21 d of age) and allotted to nursery pens with all pigs in each pen having received the same Fe treatment. In Exp. 2, a total of 1,892 newborn pigs (PIC 359 × C40; initially 1.5 ± 0.02 kg BW) within 172 litters were used. One day after birth, piglets were weighed, and 11 pigs within each litter were allotted to 1 of 6 treatments consisting of no Fe injection or 200 mg of injectable Fe provided on d 1, 3, 5, or 7 of age, or 200 mg on d 1 plus 200 mg on d 12 of age. Pigs were weaned (19 d of age) and placed in a commercial wean-to-finish facility in a total of 15 pens with equal representation of treatments in each pen. In both experiments, not providing an Fe injection after birth decreased (P &lt; 0.05) preweaning average daily gain (ADG), weaning weight, and hemoglobin and hematocrit values compared to all other treatments. In Exp. 1, increasing the age that piglets received an Fe injection until 4 or 6 d after birth provided marginal evidence for an improvement (quadratic; P = 0.070) in preweaning ADG. For the nursery period, increasing the age that piglets received an Fe injection improved (quadratic; P = 0.013) d 80 BW, but there was no evidence of a difference (P &gt; 0.10) in d 173 BW at the end of the grow-finish period. In Exp. 2, increasing the age that piglets received a 200 mg Fe injection showed no evidence of difference (P &gt; 0.10) for subsequent nursery and growing-finishing ADG. In both experiments, hemoglobin and hematocrit values were decreased (linear; P &lt; 0.05) at weaning with increasing age when pigs received an Fe injection. These experiments suggest that providing a 200 mg Fe injection within 7 d after farrowing is sufficient for optimizing preweaning and subsequent growth performance.


2020 ◽  
Vol 98 (Supplement_3) ◽  
pp. 86-87
Author(s):  
Hayden E Williams ◽  
Ryan T Maurer ◽  
Brittany Carrender ◽  
Joel M DeRouchey ◽  
Jason C Woodworth ◽  
...  

Abstract Weaned pigs (n=1,722; 5.9 kg BW) were used in a 53-d study evaluating the effects of Fe injection timing on subsequent nursery pig performance. Treatments consisted of a negative control for piglets receiving no Fe injection or 200-mg of injectable Fe (GleptoForte, Ceva Animal Health, Lenexa, KS) provided on d 1, 3, 5, or 7 of age, or 200-mg on d 1 plus an additional 200-mg injection on d 12. At weaning, pigs were placed in a commercial wean-to-finish facility in a total of 15 pens with equal representation of treatments in each pen. Pigs were weighed on d 73 after birth to determine subsequent nursery growth performance. Growth data were analyzed (GLIMMIX procedure of SAS) as a completely randomized design with individual pig as the experimental unit and pen as a random effect. Increasing the age that piglets received a 200-mg Fe injection showed no evidence of difference (P &gt;0.10) for subsequent nursery ADG (Table 1). Not providing an Fe injection after birth decreased (P=0.0001) subsequent nursery ADG and decreased (P=0.0001) d 73 BW compared to all other treatments. Providing a 200-mg injection of Fe on d 1 plus a 200-mg injection on d 12 decreased (P=0.010) subsequent nursery ADG and decreased (P=0.024) d 73 BW compared to pigs receiving a 200-mg injection on d 1 only. There was no evidence of difference (P &gt;0.10) for nursery mortality amongst the treatments. These results suggest that providing a 200-mg Fe injection within 7 d after farrowing is sufficient for optimizing subsequent nursery growth performance. The additional 200-mg Fe injection at d 12 decreased subsequent nursery growth performance and ending BW.


2019 ◽  
Vol 97 (Supplement_2) ◽  
pp. 195-196
Author(s):  
Hayden E Williams ◽  
Joel M DeRouchey ◽  
Jason C Woodworth ◽  
Steve S Dritz ◽  
Mike D Tokach ◽  
...  

Abstract Newborn pigs (n = 336; 1.7 kg BW) were used in a 21-d study evaluating the effects of increasing injectable Fe on preweaning pig performance and blood Fe status. A total of 28 litters were used and at processing (d 3 after farrowing) all piglets were weighed and six barrows and six gilts/litter were allotted to 1 of 6 treatments in a CRD. Treatments consisted of a negative control receiving no Fe injection and increasing injectable Fe (Gleptoforte, Ceva Animal Health, Lenexa, KS) to achieve 50, 100, 150, 200-mg, or 200-mg plus a 100-mg injection on d 11 post-farrowing. Piglets were weighed and bled on d 3, 11, and 21 of age to determine growth performance and blood Fe status. Preweaned pig growth data and hematological criteria were evaluated using individual pig as the experimental unit with hematological criteria analyzed as a repeated measure. Increasing injectable Fe up to 100-mg improved (quadratic; P < 0.05) ADG and d 21 BW with no further improvement thereafter (Table 1).There were no evidence of differences (P > 0.10) between the 200-mg and 200 + 100-mg treatments for growth. Significant treatment×day interactions (P < 0.001) were observed for hemoglobin (Hgb) and hematocrit (Hct). The interactions were the result of decreased values for pigs receiving no Fe injection or an Fe injection of 100-mg or less, while pigs receiving an Fe injection greater than 100-mg had increased values at d 21. Pigs receiving the 200 + 100-mg treatment had increased (P < 0.05) Hgb and Hct values compared to pigs receiving a single 200-mg Fe injection on d 21. Results suggest that a 100-mg Fe injection is sufficient for growth performance during the preweaning phase, but an Fe injection greater than 100-mg is needed to maximize blood criteria. An extra 100-mg Fe injection at d 11 did not influence growth performance but does increase Hgb and Hct at weaning.


2020 ◽  
Vol 98 (8) ◽  
Author(s):  
Hayden E Williams ◽  
Joel M DeRouchey ◽  
Jason C Woodworth ◽  
Steven S Dritz ◽  
Michael D Tokach ◽  
...  

Abstract A total of 336 newborn pigs (DNA 241 × 600, initially 1.75 ± 0.05 kg bodyweight [BW]) from 28 litters were used in a 63-d study evaluating the effects of increasing injectable Fe dose on suckling and subsequent nursery pig performance and blood Fe status. GleptoForte (Ceva Animal Health, LLC, Lenexa, KS) contains gleptoferron which is an Fe macromolecule complex that is commercially used as an injectable Fe source for suckling piglets. On the day of processing (day 3 after birth), all piglets were weighed and 6 barrows and 6 gilts per litter were allotted within sex to 1 of 6 treatments in a completely randomized design. Treatments consisted of a negative control receiving no Fe injection and increasing injectable Fe to achieve either 50, 100, 150, 200 mg, or 200 mg plus a 100 mg injection on day 11 after birth. Pigs were weaned (~21 d of age) and allotted to nursery pens based on BW and corresponding treatment in a completely randomized design. During lactation, increasing injectable Fe up to 100 mg improved (quadratic; P &lt; 0.05) average daily gain (ADG) and day 21 BW with no further improvement thereafter. There was no evidence of differences (P &gt; 0.10) observed between the 200 mg and 200 mg + 100 mg treatments for growth. For the nursery period, increasing Fe dosage increased (linear; P &lt; 0.05) ADG, average daily feed intake, and day 42 BW. There was no evidence of differences (P &gt; 0.10) between the 200 mg and 200 mg + 100 mg treatments for nursery growth. For blood criteria, significant treatment × day interactions (P = 0.001) were observed for hemoglobin (Hb) and hematocrit (Hct). The interactions occurred because pigs that had &lt;150 mg of injectable Fe had decreased values to day 21 and then increased to day 63 while pigs with 150 or 200 mg of injectable Fe had increased values to day 21 then stayed relatively constant to day 63. In summary, piglet performance during lactation was maximized at 100 mg while nursery growth performance and blood Fe status were maximized with a 200 mg Fe injection at processing. Providing an additional 100 mg of Fe on day 11 of age increased Hb, and Hct values at weaning and 14 d into the nursery but did not provide a growth performance benefit in lactation or nursery. These results indicate that providing 200 mg of injectable Fe provided from GleptoForte is sufficient to optimize lactation and subsequent nursery growth performance and blood Fe status.


2019 ◽  
Vol 97 (Supplement_2) ◽  
pp. 86-87
Author(s):  
Jason Frank ◽  
Emily Sholtz ◽  
Casey Neill ◽  
Jon De Jong

Abstract Lactose is a critical nutrient in post weaning diets to help pigs transition from sows’ milk to dry feed. The objective of this study was to evaluate the effects of increasing dietary lactose level on nursery pig performance. For this trial 1,080 weaned pigs (PIC 359 x 1050; BW = 6.24 kg; 21 d) were fed 5 lactose programs using a feed budget. Program A = 24, 18, 7%; B = 20, 14, 5%; C =16, 10, 3%; D = 12, 6, 1%; and E = 8, 2, 0% lactose for Phase 1, 2, and 3; respectively. The feed budget for Phase 1 (d 0–7), 2 (d 7–14), and 3 (d 14–20) was 0.91, 3.4, and 4.5 kg/pig; respectively. A common Phase 4 (d 20–48) diet (0% lactose) was fed ad libitum. There was a quadratic response to lactose level in treatments A through E for Phase 1 ADFI (89, 71, 73, 73, 89 g/d; respectively, P = 0.034) and G:F (1.09, 1.33, 1.14, 1.15, 0.91; respectively, P = 0.042). Treatment A through E Phase 1 ADG was 100, 95, 91, 82, and 82 g/d, and Phase 2 ADG (Linear, P = 0.023) was 322, 313, 318, 304, and 295 g/d; respectively. The result was a linear trend for increased BW at the end of Phase 2 (P = 0.10) for treatments A through E (9.21, 9.10, 9.16, 9.00, 8.86 kg; respectively). Although feed cost/pig increased as lactose level increased (Linear, P = 0.041), there was no significant response in margin over feed cost/pig during the overall nursery period for treatments A through E ($15.31, $16.41, $16.22, $15.87, $16.04; respectively). In conclusion, pig performance improved during Phase 1 and 2 with increasing level of dietary lactose. These results confirm previous research showing the importance of dietary lactose in weaned pig diets.


2019 ◽  
Vol 97 (Supplement_2) ◽  
pp. 209-210
Author(s):  
Hayden E Williams ◽  
Cierra Roubicek ◽  
Joel M DeRouchey ◽  
Jason C Woodworth ◽  
Steve S Dritz ◽  
...  

Abstract Weaned pigs (n = 311; 5.9 kg BW) were used in a 59-d study evaluating the effects of Fe injection timing after birth on nursery pig performance and hematological criteria. Pigs were weaned at 21 d and allotted to pens based on preweaning Fe treatment with BW balanced across pens within a treatment with 5 or 6 pigs/pen and 10 pens/treatment. The preweaning treatments were a negative control receiving no Fe injection or 200-mg of injectable Fe (Gleptoforte, Ceva Animal Health, Lenexa, KS) provided in a single injection on d 2, 4, 6, 8, or 10 after birth. All pigs were fed common diets after weaning that contained 110 mg/kg of added Fe as FeSO4 provided from the trace mineral premix. Growth data were analyzed as a completely randomized design with pen as the experimental unit. Hematological criteria were measured as a repeated measure with pig as the experimental unit. Overall, increasing the age of pigs receiving a 200-mg Fe injection from 2 to 4 or 6 d after birth increased (quadratic; P = 0.013) d 80 ending BW with a decrease in BW when Fe was provided on d 8 or 10 (Table 1). Not providing an Fe injection after birth worsened (P < 0.05) ADG, ADFI, and d 80 ending BW. Significant treatment×day interactions (P < 0.001) were observed for Hgb and Hct values. These interactions occurred because pigs not receiving an Fe injection after birth had values that increased from d 21 to 35 while pigs receiving an Fe injection had values that decreased from d 21 to 35. While it is common practice to provide an Fe injection within the first 48 hours of birth, these results suggest delaying injection until d 4 or 6 may increase nursery final weight.


2019 ◽  
Vol 97 (Supplement_2) ◽  
pp. 196-197
Author(s):  
Hayden E Williams ◽  
Joel M DeRouchey ◽  
Jason C Woodworth ◽  
Steve S Dritz ◽  
Mike D Tokach ◽  
...  

Abstract Weaned pigs (n = 308; 5.7 kg BW) were used in a 42-d study evaluating the effects of increasing injectable Fe dose at processing (d 3 after farrowing) on subsequent nursery pig performance and hematological criteria. Pigs were weaned on d 21 and allotted to pens based on previous Fe treatment with BW balanced across pens within a treatment with 5 or 6 pigs/pen and 10 pens/treatment. Treatments applied at processing were a negative control receiving no Fe injection or increasing injectable Fe (Gleptoforte, Ceva Animal Health, Lenexa, KS) to provide 50, 100, 150, 200-mg, or 200-mg plus 100-mg on d 11 post-farrowing. All pigs were fed the same diets after weaning containing 110 mg/kg of Fe from FeSO4 provided from the trace mineral premix. Growth data were analyzed as a CRD with pen as the experimental unit. Hematological criteria were analyzed as a repeated measure with pig as the experimental unit. Overall, increasing injectable Fe improved (linear; P < 0.05) ADG and ADFI (Table 1). Increasing injectable Fe up to 150 mg improved (quadratic; P = 0.011) G:F with a worsening G:F thereafter. There was no evidence of difference in growth performance (P > 0.10) between the 200-mg and the 200 + 100 mg injectable Fe treatments. Significant treatment×day interactions (P < 0.001) were observed for Hgb and Hct because pigs receiving an Fe injection less than 150-mg had increasing values through nursery while all other pigs had values remaining constant until d 63 after birth with no evidence of difference (P > 0.10) amongst all treatments at d 63 after birth. These results suggest that providing a 200-mg Fe injection at processing provides the greatest growth performance in the nursery and Fe in the diet is sufficient to meet the pigs’ Fe requirement to restore blood Fe status at the end of the nursery.


2018 ◽  
Vol 2 (1) ◽  
pp. 62-73 ◽  
Author(s):  
J A Feldpausch ◽  
R G Amachawadi ◽  
M D Tokach ◽  
H M Scott ◽  
S S Dritz ◽  
...  

Abstract Two 47-d experiments were conducted with 21-d-old weaned pigs (PIC 1050, initially 6.1 kg) to determine the effects of feeding low or high doses of chlortetracycline (CTC) and antibiotic alternatives (Cu, Zn, and essential oil [EO]), alone or in combination, on growth performance. On d 5 postweaning, pens of 5 pigs were allotted to diet treatments with 8 (exp. 1) or 7 (exp. 2) replicate pens per treatment. In exp. 1, treatments were fed from d 5 to 26 postweaning and arranged in a 2 × 3 factorial with main effects of added ZnO (0 vs. 2,500 ppm of Zn) and CTC (0, 55, or 441 ppm). In exp. 2, treatments were fed from d 5 to 33 and structured in a (2 × 2 × 2) + 2 factorial with main effects of added CuSO4 (0 vs. 125 ppm Cu), added ZnO (0 vs. 3,000 ppm Zn from d 5 to 12 and 2,000 ppm Zn from d 12 to 33), and Regano EX (0 vs. 0.1% Regano EX containing 5% Origanum oil). The 2 additional treatments were subtherapeutic (55 ppm) and therapeutic (441 ppm) levels of CTC. Following the treatment period, a common diet without antimicrobial was fed until d 47. All diets contained 16.5 ppm Cu and 110 ppm Zn from the trace mineral premix. In exp. 1, no ZnO × CTC interactions were observed. Feeding ZnO increased (P &lt; 0.05) ADG, ADFI, and BW during the treatment period and increased (P &lt; 0.05) ADG and ADFI overall (d 5 to 47). Pigs fed CTC had increased (linear, P &lt; 0.05) ADG, ADFI, and BW during the treatment period and had marginally significant increases (linear, P &lt; 0.10) in overall ADG and ADFI, but overall G:F tended (quadratic, P = 0.070) to increase then decrease as CTC increased. During the treatment period in exp. 2, EO did not affect ADG or ADFI, whereas pharmacological levels of Cu, Zn, and CTC increased (P &lt; 0.05) ADG with coinciding increases (P = 0.055, 0.006, and linear 0.079, respectively) in ADFI. Copper, Zn, and CTC did not affect G:F. EO decreased (P = 0.009) G:F. Diet treatments had minimal carryover effects on subsequent nursery pig growth performance. Overall from d 5 to 47, Cu increased (P = 0.018) ADG, Zn increased (P &lt; 0.05) ADG and ADFI, and EO tended to decrease (P = 0.086) G:F. In conclusion, increased dietary Cu, Zn, or CTC improved weanling pig performance while EO elicited no growth benefits. The benefits of added Zn from ZnO and CTC were additive and could be included together in diets to maximize growth performance of weaned pigs.


2020 ◽  
Vol 98 (Supplement_3) ◽  
pp. 229-230
Author(s):  
Paige K Isensee ◽  
Sarah Albers ◽  
Lindsey Wichman ◽  
Autumn Thoma ◽  
Young Dal Jang

Abstract Two experiments were conducted to evaluate the effect of creep feed (CF) and its nutrient level on growth performance of suckling and weaning pigs. In Exp. 1, eight litters (d 20 of age) were allotted to 2 treatments based on breed, litter size and weight as follows: no-CF (n=3) and CF (n=5; offered from 8 days before weaning). At weaning (d 28 of age), the pigs were divided into 3 treatments (6 pigs/pen, 3 replicates; initial BW: 9.66±0.34 kg) balanced with gender, weight, and breed as follows: eaters, noneaters, and no-CF. In Exp. 2, seven litters (d 12 of age) were allotted to 2 treatments as follows: HN (n=4): CF with fish meal (3%), blood meal (2.4%), and whey (15%), and LN (n=3): CF without those ingredients. At weaning (d 25 of age), eater pigs were divided into 2 treatments (6 pigs/pen, 3 replicates; initial BW: 7.53±0.97 kg) as follows: HN-eaters and LN-eaters. In both experiments, the pigs were fed a common nursery diet for 21 days. The CF was mixed with 1% Cr2O3 to measure fecal color for eater/noneater categorization. Piglet weaning weight was not different among eaters and non-eaters in both experiments (in Exp. 1, P=0.99; 9.35, 9.33, and 9.20 kg for eaters, noneaters, and no-CF, respectively). There was no difference on overall nursery growth performance in both experiments. The HN-eaters tended to have greater ADG (P=0.08; 0.506 vs. 0.427 g/d for HN-eaters and LN-eaters, respectively) and G:F (P=0.09; 0.889 vs. 0.717, respectively) than LN-eaters in d 7-14 postweaning in Exp. 2. The CF intake and percentage of eaters/litter (P=0.60; 85.6 and 80.87% for LN and HN, respectively) in Exp. 2 were not different between treatments. In conclusion, CF did not affect overall piglet growth in suckling and nursery phases, but nutrient level might affect early nursery pig growth.


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