scholarly journals 258 Effects of iron administration timing on subsequent nursery performance

2020 ◽  
Vol 98 (Supplement_3) ◽  
pp. 86-87
Author(s):  
Hayden E Williams ◽  
Ryan T Maurer ◽  
Brittany Carrender ◽  
Joel M DeRouchey ◽  
Jason C Woodworth ◽  
...  
Keyword(s):  
Growth Performance ◽  
Animal Health ◽  
Random Effect ◽  
Negative Control ◽  
Experimental Unit ◽  
Injection Timing ◽  
Growth Data ◽  
Iron Administration ◽  
Randomized Design ◽  
D 12

Abstract Weaned pigs (n=1,722; 5.9 kg BW) were used in a 53-d study evaluating the effects of Fe injection timing on subsequent nursery pig performance. Treatments consisted of a negative control for piglets receiving no Fe injection or 200-mg of injectable Fe (GleptoForte, Ceva Animal Health, Lenexa, KS) provided on d 1, 3, 5, or 7 of age, or 200-mg on d 1 plus an additional 200-mg injection on d 12. At weaning, pigs were placed in a commercial wean-to-finish facility in a total of 15 pens with equal representation of treatments in each pen. Pigs were weighed on d 73 after birth to determine subsequent nursery growth performance. Growth data were analyzed (GLIMMIX procedure of SAS) as a completely randomized design with individual pig as the experimental unit and pen as a random effect. Increasing the age that piglets received a 200-mg Fe injection showed no evidence of difference (P >0.10) for subsequent nursery ADG (Table 1). Not providing an Fe injection after birth decreased (P=0.0001) subsequent nursery ADG and decreased (P=0.0001) d 73 BW compared to all other treatments. Providing a 200-mg injection of Fe on d 1 plus a 200-mg injection on d 12 decreased (P=0.010) subsequent nursery ADG and decreased (P=0.024) d 73 BW compared to pigs receiving a 200-mg injection on d 1 only. There was no evidence of difference (P >0.10) for nursery mortality amongst the treatments. These results suggest that providing a 200-mg Fe injection within 7 d after farrowing is sufficient for optimizing subsequent nursery growth performance. The additional 200-mg Fe injection at d 12 decreased subsequent nursery growth performance and ending BW.

scholarly journals PSVI-19 Evaluating the effects of day of iron injection after farrowing on nursery performance and hematological criteria

2019 ◽  
Vol 97 (Supplement_2) ◽  
pp. 209-210
Author(s):  
Hayden E Williams ◽  
Cierra Roubicek ◽  
Joel M DeRouchey ◽  
Jason C Woodworth ◽  
Steve S Dritz ◽  
...  
Keyword(s):  
Animal Health ◽  
Negative Control ◽  
Repeated Measure ◽  
Experimental Unit ◽  
Injection Timing ◽  
Growth Data ◽  
Significant Treatment ◽  
Randomized Design ◽  
Nursery Pig ◽  
Pig Performance

Abstract Weaned pigs (n = 311; 5.9 kg BW) were used in a 59-d study evaluating the effects of Fe injection timing after birth on nursery pig performance and hematological criteria. Pigs were weaned at 21 d and allotted to pens based on preweaning Fe treatment with BW balanced across pens within a treatment with 5 or 6 pigs/pen and 10 pens/treatment. The preweaning treatments were a negative control receiving no Fe injection or 200-mg of injectable Fe (Gleptoforte, Ceva Animal Health, Lenexa, KS) provided in a single injection on d 2, 4, 6, 8, or 10 after birth. All pigs were fed common diets after weaning that contained 110 mg/kg of added Fe as FeSO4 provided from the trace mineral premix. Growth data were analyzed as a completely randomized design with pen as the experimental unit. Hematological criteria were measured as a repeated measure with pig as the experimental unit. Overall, increasing the age of pigs receiving a 200-mg Fe injection from 2 to 4 or 6 d after birth increased (quadratic; P = 0.013) d 80 ending BW with a decrease in BW when Fe was provided on d 8 or 10 (Table 1). Not providing an Fe injection after birth worsened (P < 0.05) ADG, ADFI, and d 80 ending BW. Significant treatment×day interactions (P < 0.001) were observed for Hgb and Hct values. These interactions occurred because pigs not receiving an Fe injection after birth had values that increased from d 21 to 35 while pigs receiving an Fe injection had values that decreased from d 21 to 35. While it is common practice to provide an Fe injection within the first 48 hours of birth, these results suggest delaying injection until d 4 or 6 may increase nursery final weight.

scholarly journals 260 Effects of iron administration timing on pre-weaning performance and hematological criteria in pigs

2020 ◽  
Vol 98 (Supplement_3) ◽  
pp. 88-89
Author(s):  
Hayden E Williams ◽  
Ryan T Maurer ◽  
Brittany Carrender ◽  
Joel M DeRouchey ◽  
Jason C Woodworth ◽  
...  
Keyword(s):  
Growth Performance ◽  
Animal Health ◽  
Injection Timing ◽  
Iron Administration ◽  
Newborn Pigs ◽  
Pig Performance ◽  
D 20 ◽  
D 12 ◽  
Administration Timing

Abstract Newborn pigs (n=1,892; 1.5 kg BW) were used in a 20-d study evaluating the effects of Fe injection timing after birth on preweaned pig performance and blood criteria. A total of 172 litters were used. One d after farrowing, piglets were weighed, and 11 pigs within each litter were allotted to 1 of 6 treatments in a CRD. Treatments consisted of pigs receiving no Fe injection or 200-mg of injectable Fe (GleptoForte, Ceva Animal Health, Lenexa, KS) provided on d 1, 3, 5, or 7 of age, or 200-mg on d 1 plus 200-mg on d 12. 1 pig/litter received no Fe injection and 2 pigs/litter were placed on all other treatments. Piglets were weighed on d 1 and 20 after birth to determine growth performance and bled on d 20 to determine Fe status. Increasing the age that piglets received the Fe injection tended to decrease (linear; P=0.080) ADG. Not providing an Fe injection decreased (P=0.0001) overall ADG and d 20 BW compared to all other treatments. Hemoglobin and Hct decreased (linear; P&lt; 0.05) with increasing age when pigs received an Fe injection. There was no evidence of differences (P &gt;0.10) between the pigs receiving a 200-mg injection on d 1 and d 12 compared to those receiving the Fe on d 1 only. Pigs not provided an Fe injection had decreased (P=0.0001) Hb and Hct values compared to pigs receiving an Fe injection. Pigs receiving the 200-mg injection on d 1 and 12 had increased (P=0.0001) Hb and Hct values compared to pigs receiving 200-mg on d 1 only. Results suggest that providing a 200-mg Fe injection within 7 d after farrowing is sufficient for optimizing preweaning growth performance. The additional 200-mg Fe injection at d 12 did not influence growth performance but does increase Hb and Hct at weaning.

scholarly journals PSV-13 Effects of increasing iron dosage in newborn pigs on subsequent nursery performance and hematological criteria

2019 ◽  
Vol 97 (Supplement_2) ◽  
pp. 196-197
Author(s):  
Hayden E Williams ◽  
Joel M DeRouchey ◽  
Jason C Woodworth ◽  
Steve S Dritz ◽  
Mike D Tokach ◽  
...  
Keyword(s):  
Growth Performance ◽  
Animal Health ◽  
Negative Control ◽  
Repeated Measure ◽  
Experimental Unit ◽  
Growth Data ◽  
Significant Treatment ◽  
D 63 ◽  
Nursery Pig ◽  
Pig Performance

Abstract Weaned pigs (n = 308; 5.7 kg BW) were used in a 42-d study evaluating the effects of increasing injectable Fe dose at processing (d 3 after farrowing) on subsequent nursery pig performance and hematological criteria. Pigs were weaned on d 21 and allotted to pens based on previous Fe treatment with BW balanced across pens within a treatment with 5 or 6 pigs/pen and 10 pens/treatment. Treatments applied at processing were a negative control receiving no Fe injection or increasing injectable Fe (Gleptoforte, Ceva Animal Health, Lenexa, KS) to provide 50, 100, 150, 200-mg, or 200-mg plus 100-mg on d 11 post-farrowing. All pigs were fed the same diets after weaning containing 110 mg/kg of Fe from FeSO4 provided from the trace mineral premix. Growth data were analyzed as a CRD with pen as the experimental unit. Hematological criteria were analyzed as a repeated measure with pig as the experimental unit. Overall, increasing injectable Fe improved (linear; P < 0.05) ADG and ADFI (Table 1). Increasing injectable Fe up to 150 mg improved (quadratic; P = 0.011) G:F with a worsening G:F thereafter. There was no evidence of difference in growth performance (P > 0.10) between the 200-mg and the 200 + 100 mg injectable Fe treatments. Significant treatment×day interactions (P < 0.001) were observed for Hgb and Hct because pigs receiving an Fe injection less than 150-mg had increasing values through nursery while all other pigs had values remaining constant until d 63 after birth with no evidence of difference (P > 0.10) amongst all treatments at d 63 after birth. These results suggest that providing a 200-mg Fe injection at processing provides the greatest growth performance in the nursery and Fe in the diet is sufficient to meet the pigs’ Fe requirement to restore blood Fe status at the end of the nursery.

scholarly journals PSV-12 Effects of increasing iron dosage in newborn pigs on preweaning performance and hematological criteria

2019 ◽  
Vol 97 (Supplement_2) ◽  
pp. 195-196
Author(s):  
Hayden E Williams ◽  
Joel M DeRouchey ◽  
Jason C Woodworth ◽  
Steve S Dritz ◽  
Mike D Tokach ◽  
...  
Keyword(s):  
Growth Performance ◽  
Animal Health ◽  
Negative Control ◽  
Repeated Measure ◽  
Experimental Unit ◽  
Growth Data ◽  
Significant Treatment ◽  
Newborn Pigs ◽  
Pig Performance

Abstract Newborn pigs (n = 336; 1.7 kg BW) were used in a 21-d study evaluating the effects of increasing injectable Fe on preweaning pig performance and blood Fe status. A total of 28 litters were used and at processing (d 3 after farrowing) all piglets were weighed and six barrows and six gilts/litter were allotted to 1 of 6 treatments in a CRD. Treatments consisted of a negative control receiving no Fe injection and increasing injectable Fe (Gleptoforte, Ceva Animal Health, Lenexa, KS) to achieve 50, 100, 150, 200-mg, or 200-mg plus a 100-mg injection on d 11 post-farrowing. Piglets were weighed and bled on d 3, 11, and 21 of age to determine growth performance and blood Fe status. Preweaned pig growth data and hematological criteria were evaluated using individual pig as the experimental unit with hematological criteria analyzed as a repeated measure. Increasing injectable Fe up to 100-mg improved (quadratic; P < 0.05) ADG and d 21 BW with no further improvement thereafter (Table 1).There were no evidence of differences (P > 0.10) between the 200-mg and 200 + 100-mg treatments for growth. Significant treatment×day interactions (P < 0.001) were observed for hemoglobin (Hgb) and hematocrit (Hct). The interactions were the result of decreased values for pigs receiving no Fe injection or an Fe injection of 100-mg or less, while pigs receiving an Fe injection greater than 100-mg had increased values at d 21. Pigs receiving the 200 + 100-mg treatment had increased (P < 0.05) Hgb and Hct values compared to pigs receiving a single 200-mg Fe injection on d 21. Results suggest that a 100-mg Fe injection is sufficient for growth performance during the preweaning phase, but an Fe injection greater than 100-mg is needed to maximize blood criteria. An extra 100-mg Fe injection at d 11 did not influence growth performance but does increase Hgb and Hct at weaning.

scholarly journals 363 Evaluating the effects of day of iron injection after farrowing on preweaning performance and hematological criteria

2019 ◽  
Vol 97 (Supplement_2) ◽  
pp. 151-152
Author(s):  
Cierra Roubicek ◽  
Hayden E Williams ◽  
Joel M DeRouchey ◽  
Jason C Woodworth ◽  
Steve S Dritz ◽  
...  
Keyword(s):  
Growth Performance ◽  
Animal Health ◽  
Negative Control ◽  
Injection Timing ◽  
Significant Treatment ◽  
Newborn Pigs ◽  
Pig Performance ◽  
D 12

Abstract Newborn pigs (n = 324; 1.6 kg BW) were used in an 19-d study evaluating the effects of Fe injection timing after birth on preweaned pig performance and blood criteria. A total of 27 litters were used, with the number of pigs per sow equalized on each day of farrowing. Two d after farrowing, all piglets were weighed, and six barrows and six gilts within each litter were allotted to 1 of 6 treatments in a CRD. Treatments consisted of a negative control receiving no Fe injection or 200 mg of injectable Fe (Gleptoforte, Ceva Animal Health, Lenexa, KS) provided on d 2, 4, 6, 8, or 10 after farrowing. Piglets were weighed and bled on d 2, 12, and 21 after birth to determine growth performance and blood Fe status. Overall, increasing the age that piglets received a 200 mg Fe injection until 4 or 6 d after birth tended to increase (quadratic; P = 0.065) ADG (Table 1). Not providing an Fe injection tended to decrease (P = 0.070) overall ADG and decreased (P = 0.0003) d 21 BW compared to all other treatments. Significant treatment×day interactions (P < 0.001) were observed for hemoglobin (Hgb) and hematocrit (Hct). The interactions occurred because pigs injected with 200 mg of Fe on d 2, 4, 6, or 8 after birth had increasing values until d 21 after birth, while pigs receiving a 200 mg Fe injection on d 10 after birth had decreasing values to d 12 then increasing values to d 21. Pigs not provided an Fe injection after birth had decreasing values to d 21. These results suggest that providing a 200 mg Fe injection on d 4 or 6 after farrowing provided the greatest preweaning growth performance and blood Fe status until weaning.

scholarly journals Effects of increasing Fe dosage in newborn pigs on suckling and subsequent nursery performance and hematological and immunological criteria

2020 ◽  
Vol 98 (8) ◽  
Author(s):  
Hayden E Williams ◽  
Joel M DeRouchey ◽  
Jason C Woodworth ◽  
Steven S Dritz ◽  
Michael D Tokach ◽  
...  
Keyword(s):  
Growth Performance ◽  
Animal Health ◽  
Average Daily Gain ◽  
Negative Control ◽  
Significant Treatment ◽  
Randomized Design ◽  
Nursery Pig ◽  
Newborn Pigs ◽  
Completely Randomized Design ◽  
Pig Performance

Abstract A total of 336 newborn pigs (DNA 241 × 600, initially 1.75 ± 0.05 kg bodyweight [BW]) from 28 litters were used in a 63-d study evaluating the effects of increasing injectable Fe dose on suckling and subsequent nursery pig performance and blood Fe status. GleptoForte (Ceva Animal Health, LLC, Lenexa, KS) contains gleptoferron which is an Fe macromolecule complex that is commercially used as an injectable Fe source for suckling piglets. On the day of processing (day 3 after birth), all piglets were weighed and 6 barrows and 6 gilts per litter were allotted within sex to 1 of 6 treatments in a completely randomized design. Treatments consisted of a negative control receiving no Fe injection and increasing injectable Fe to achieve either 50, 100, 150, 200 mg, or 200 mg plus a 100 mg injection on day 11 after birth. Pigs were weaned (~21 d of age) and allotted to nursery pens based on BW and corresponding treatment in a completely randomized design. During lactation, increasing injectable Fe up to 100 mg improved (quadratic; P &lt; 0.05) average daily gain (ADG) and day 21 BW with no further improvement thereafter. There was no evidence of differences (P &gt; 0.10) observed between the 200 mg and 200 mg + 100 mg treatments for growth. For the nursery period, increasing Fe dosage increased (linear; P &lt; 0.05) ADG, average daily feed intake, and day 42 BW. There was no evidence of differences (P &gt; 0.10) between the 200 mg and 200 mg + 100 mg treatments for nursery growth. For blood criteria, significant treatment × day interactions (P = 0.001) were observed for hemoglobin (Hb) and hematocrit (Hct). The interactions occurred because pigs that had &lt;150 mg of injectable Fe had decreased values to day 21 and then increased to day 63 while pigs with 150 or 200 mg of injectable Fe had increased values to day 21 then stayed relatively constant to day 63. In summary, piglet performance during lactation was maximized at 100 mg while nursery growth performance and blood Fe status were maximized with a 200 mg Fe injection at processing. Providing an additional 100 mg of Fe on day 11 of age increased Hb, and Hct values at weaning and 14 d into the nursery but did not provide a growth performance benefit in lactation or nursery. These results indicate that providing 200 mg of injectable Fe provided from GleptoForte is sufficient to optimize lactation and subsequent nursery growth performance and blood Fe status.

PSIV-11 Effects of Phytogenic Feed Additives on Growth Performance Traits of Finishing Swine

2021 ◽  
Vol 99 (Supplement_1) ◽  
pp. 187-188
Author(s):  
Pengcheng Xue ◽  
Don W Giesting ◽  
Mark D Newcomb ◽  
Chad M Pilcher ◽  
Matthew J Ritter
Keyword(s):  
Growth Performance ◽  
Random Effect ◽  
Live Weight ◽  
Feed Additives ◽  
Experimental Unit ◽  
Finishing Pigs ◽  
Performance Traits ◽  
And Gender ◽  
Dietary Treatments ◽  
Commercial Research

Abstract This study was conducted at a commercial research facility and utilized 1,092 finishing pigs (PIC® 337 × Camborough®) in a RCBD with 3 dietary treatments to determine the effects of commercially available phytogenic feed additives on growth performance traits in finishing swine for the last 35 d prior to marketing. The dietary treatments were as follows: 1) Control; 2) Aromex Pro® (AP; Delacon) fed at 0.01%; and 3) Ambitine® (AM; PMI) fed at 0.1%. Pens with 13 pigs/pen and 0.66 m2/pig were randomly allotted to treatments on the basis of live weight and gender. Pigs had ad libitum access to corn-soy diets that met or exceeded the pig’s requirements (NRC, 2012). Aromex Pro® and Ambitine® were added to the diets at the expense of corn. Dietary treatments started on day 0 (BW = 97.7 kg; SEM = 1.04) and were fed throughout the 35 d trial period. On d 21, the two heaviest pigs per pen were marketed, while the remaining pigs in each pen were marketed on d 35. Pigs and feeders were weighed on d 0, 21, and 35. Data were analyzed by using PROC MIXED of SAS® version 9.4, and pen was the experimental unit. The model included the fixed effect of treatment and random effect of replicate. Pre-planned orthogonal contrasts were used to compare AP vs. Control and AM vs. Control. Feeding AP or AM for the last 35 d in finishing both improved (P &lt; 0.05) ADG by 4%, ADFI by 3% and final BW by 1.6 kg over Control, but did not change feed to gain or mortality. These data demonstrate that phytogenic feed additives can improve growth performance traits in finishing swine.

scholarly journals Effect of drying and/or warming piglets at birth under warm farrowing room temperatures on piglet rectal temperature over the first 24 h after birth

2021 ◽  
Author(s):  
Katherine D Vande Pol ◽  
Andres F Tolosa ◽  
Caleb M Shull ◽  
Catherine B Brown ◽  
Stephan A S Alencar ◽  
...  
Keyword(s):  
Birth Weight ◽  
Birth Control ◽  
Rectal Temperature ◽  
Fixed Effects ◽  
Random Effect ◽  
Repeated Measure ◽  
Experimental Unit ◽  
Concentration Data ◽  
Randomized Design ◽  
Completely Randomized Design

Abstract Piglets experience a decline in body temperature immediately after birth, and both drying and warming piglets at birth reduces this. However, these interventions may have less effective at higher farrowing room temperatures. This study was carried out at a commercial facility to compare the effect of drying and/or warming piglets at birth on postnatal rectal temperature (RT) under relatively warm farrowing room temperatures (26.6 ± 2.09°C). Forty-five sows/litters were used in a completely randomized design to compare three Intervention Treatments (applied at birth): Control (no treatment); Warming (piglets placed in a plastic box under a heat lamp for 30 min); Drying+Warming (piglets dried with desiccant and warmed as above). Temperatures in the warming boxes over the study period averaged 37.7 ± 2.75°C. At birth, piglets were weighed; RT temperature was measured at 0, 10, 20, 30, 45, 60, 120, and 1440 min after birth. Blood samples were collected at 24 h after birth from a subsample of one piglet from each birth weight quartile within each litter to measure plasma immunocrit concentration. Data were analyzed using PROC MIXED of SAS with litter as the experimental unit; and piglet a subsample of litter. The model for analysis of piglet rectal temperature included fixed effects of treatment, measurement time (repeated measure), the interaction, and the random effect of sow. Compared to the Control, piglet RT were higher (P ≤ 0.05) for the Warming treatment between 10 and 60 min, and higher (P ≤ 0.05) for the Drying+Warming treatment between 10 and 120 min after birth. Rectal temperatures were higher (P ≤ 0.05) for the Drying+Warming than the Warming treatment between 20 and 120 min. Responses to drying and/or warming were greater for low birth weight piglets (&lt; 1.0 kg) than heavier littermates, but were generally less than observed in previous experiments with similar treatments carried out under cooler temperatures. Piglet immunocrit values were lower (P ≤ 0.05) for the Drying+Warming treatment compared to the other treatments, which were similar (P &gt; 0.05). Immunocrit values tended (P = 0.10) to be lower for light (&lt; 1.0 kg) compared to heavier birth weight piglets. In conclusion, drying and warming piglets at birth was more effective for reducing piglet RT decline after birth than warming alone, though the effect was less than observed in previous studies carried out under cooler farrowing room temperatures.

scholarly journals PSIII-8 Impact of SYNOVEX® ONE GRASS implantation during suckling on pre-weaning calf growth performance

2020 ◽  
Vol 98 (Supplement_3) ◽  
pp. 239-239
Author(s):  
Shane Newton ◽  
Payton Dahmer ◽  
Larry Corah ◽  
Keith Harmoney ◽  
John Jaeger ◽  
...  
Keyword(s):  
Growth Performance ◽  
Random Effect ◽  
Cost Effective ◽  
Recent Decade ◽  
Estradiol Benzoate ◽  
Beef Steers ◽  
Weaning Weight ◽  
Trenbolone Acetate ◽  
Calf Growth ◽  
Randomized Design

Abstract Historic data supports the use of pre-weaning implants to maximize beef calf weaning weight, but their use has declined over the recent decade. A total of 96 beef steers (initially 85.2 kg BW and &gt; 45 d of age) were used in a 168-d study to evaluate the effects of Synovex C® implantation during suckling on pre-weaning calf growth performance. At initial processing, calves were individually weighed and allotted in a completely randomized design to one of two treatments: 1) not implanted (control) or 2) implanted with 150 mg of trenbolone acetate and 21 mg of estradiol benzoate (SYNOVEX® ONE GRASS, Zoetis, Kalamazoo, MI). All calves were weighed on d 0 (implantation), 83, 126 and 168 (weaning), with ADG calculated for each period. Data were analyzed using the GLIMMIX procedure of SAS (v9.4, Cary, NC). There were 48 replicates per treatment, with grazing location as a random effect. While there were no detected differences in BW during the initial phases (P &gt; 0.10), implanted calves tended to have greater (P = 0.100) greater weaning weight than non-implanted calves (279 vs. 265 kg, respectively). Calves implanted with SYNOVEX® ONE GRASS had 0.8, 0.12, and 0.16 kg/d greater (P &lt; 0.05) ADG than those that were not implanted in all three phases. This resulted in an average of 0.10 kg/d greater (P = 0.002) ADG in implanted calves overall compared to the control. In conclusion, this research showed significant increases in suckling calf ADG in implanted calves compared to their non-implanted counterparts, which led to a tendency for 14-kg greater weaning weights. Additional research is warranted to consider the post-weaning growth and impact of re-implanting, but this data reinforces previous literature that suckling calf implantation continues to be cost effective for cow-calf producers.

20 Effect of Adding Bioactive Peptide in Combination of Pharmaceutical Zinc Oxide or Organic Acids on Growth Performance, Hematology Profile, and Nutrient Digestibility in Nursery Pigs

2021 ◽  
Vol 99 (Supplement_1) ◽  
pp. 22-23
Author(s):  
Richard A Mudarra ◽  
Tsung Cheng Cheng Tsai ◽  
Kristopher Bottoms ◽  
Thomas S Shieh ◽  
Casey Bradly ◽  
...  
Keyword(s):  
Growth Performance ◽  
Phase 1 ◽  
Random Effect ◽  
Positive Control ◽  
Negative Control ◽  
Nutrient Digestibility ◽  
Bioactive Peptide ◽  
Nursery Pigs ◽  
Cell Counts ◽  
High Zinc

Abstract To evaluate the effect of bioactive peptide (P) in combination with high level of zinc (HZ) or acidifiers on growth performance, complete blood cell counts (CBC) and nutrient digestibility in nursery pigs, a total of 288 weaned pigs (PIC1050xDNA600) were stratified by initial BW within gender and allotted to 1of 7 treatments. Treatments for phase 1&2 were: 1) nutrient adequate positive control with HZ (PC), 2) nutrient deficient negative control with HZ (NC, -0.13% SID Lysine by reducing fish meal), 3) NC+0.25% peptide (0.25PZ), 4) NC+0.5% peptide (0.5PZ), 5) NC+0.25% peptide with standard zinc (0.25P), 6) NC+0.5% peptide with standard zinc (0.5P), 7) as 5 + 0.1% sodium butyrate and 0.5% benzoic acid (PSB). All pigs were fed a common low Zn diet (197 ppm) during phase 3. The whole blood was obtained from a close-to-average pen-BW pig repeatedly at weaning, and at the end of phase 2 and 3 to determine CBC. Titanium dioxide was used as an indigestible marker to determine nutrient digestibility. Data were analyzed using the Mixed procedures of SAS as a RCBD with treatment as fixed effect, and BW block as random effect. In overall phase 1&2, pigs fed PSB had similar ADG and BW when compared to pigs fed 0.25PZ and both were greater than NC pigs (Table 1). With the same inclusion rate of peptide, pigs fed a high zinc diet had greater BW and ADG than pigs fed a standard zinc diet. PSB pigs had the greatest G:F ratio and nitrogen digestibility among treatments. Increasing peptide in high zinc diets gradually decreased Neutrophil-to-lymphocyte ratio. This study indicates that the improvement in growth performance from pigs fed peptide is pharmaceutical zinc dependent and acidifiers can be an alternative to replace ZnO without affecting growth performance.

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