scholarly journals PSVII-19 Characterization and Migration of Cultured Quail Primordial Germ Cells from Embryonic Blood and Gonad.

2018 ◽  
Vol 96 (suppl_3) ◽  
pp. 354-354
Author(s):  
S Yakhkeshi ◽  
S Rahimi ◽  
M Sharafi ◽  
S Hassani ◽  
G Shahverdi ◽  
...  
Keyword(s):  
Germ Cells ◽  
Primordial Germ Cells ◽  
And Migration

Memoirs: The Origin and Migration of the Primordial Germ-cells of Sphenodon punctatus

1932 ◽  
Vol s2-75 (298) ◽  
pp. 251-282
Author(s):  
MARGARET TRIBE ◽  
F.W. ROGERS BRAMBELL
Keyword(s):  
Germ Cells ◽  
Early Stage ◽  
Venous Blood ◽  
Primordial Germ Cells ◽  
Blood Stream ◽  
Yolk Sac ◽  
Amoeboid Movement ◽  
Stage Of Development ◽  
Sphenodon Punctatus ◽  
And Migration

1. The primordial germ-cells of Sphenodon originate in the yolk-sac endoderm of the area opaca all round the embiyo, but chiefly in a crescentic area in front of it. 2. They differentiate first at a very early stage of development before the differentiation of the medullary plate. 3. The primordial germ-cells are characterized by their very large size, in comparison with all the other embryonal cells, and by their content of small yolk-spherules which are sub-equal in size. 4. The primordial germ-cells migrate through the yolk-sac endoderm and mesoderm, apparently by their own power of amoeboid movement. Many of them enter the blood-islands and the sinus terminalis. 5. The primordial germ-cells enter the embryo either (1) passively in the venous blood-stream, or (2) actively by migration through the extra-embryonal endoderm and splanchnic mesoderm into the lateral walls and the mesentery of the midgut groove. 6. The primordial germ-cells in the circulation reach the neighbourhood of the germinal ridges in the dorsal aorta or its branches. They then penetrate the walls of the vessels and migrate through the intervening tissues, together with those that have reached the base of the mid-gut mesentery by way of the splanchnic mesoderm and the mid-gut wall, to the germinal ridges. 7. Many primordial germ-cells get lost during their migration. This is especially true of those travelling in the blood-stream. Such aberrant primordial germ-cells are found occasionally in almost any part of the embryo,, but occur most often in the head, especially in the region of the fore-brain. They ultimately disappear. 8. The primordial germ-cells enter the forming germinal ridges before the coelomic epithelium covering them has begun to proliferate. 9. The primordial germ-cells, having reached the germinal ridges, lose their characteristic yolk-content and enter on the prophase of the heterotypic division.

Proliferation and migration of primordial germ cells during compensatory growth in mouse embryos

Development ◽  
1981 ◽  
Vol 64 (1) ◽  
pp. 133-147
Author(s):  
P. P. L. Tam ◽  
M. H. L. Snow
Keyword(s):  
Mitomycin C ◽  
Germ Cells ◽  
Compensatory Growth ◽  
Primordial Germ Cells ◽  
Primordial Germ Cell ◽  
Primitive Streak ◽  
Mouse Embryos ◽  
Newborn Mice ◽  
Embryonic Life ◽  
And Migration

Primitive-streak-stage mouse embryos were treated with Mitomycin C injected intraperitoneally into pregnant females at 6·75–7·0 days post coitum. The newborn mice developed poorly and mortality was high during the suckling period. Many weaned survivors showed impaired fertility and poor breeding performance. Histological examination revealed a paucity of germ cells in the adult gonads. The deficiency was mainly caused by a severe reduction of the primordial germ cell population in early embryonic life, which was not fully compensated for during the compensatory growth phase of the Mitomycin C-treated embryo. Also contributing to such impaired fertility were retarded migration of the primordial germ cells into the genital ridges, poor development of the foetal gonad and secondary loss of the germ cells during gametogenesis in males.

scholarly journals Inter-species transplantation and migration of primordial germ cells in cyprinid fish

2010 ◽  
Vol 54 (10) ◽  
pp. 1479-1484 ◽  
Author(s):  
Taiju Saito ◽  
Rie Goto-Kazeto ◽  
Takafumi Fujimoto ◽  
Yutaka Kawakami ◽  
Katsutoshi Arai ◽  
...  
Keyword(s):  
Germ Cells ◽  
Primordial Germ Cells ◽  
Cyprinid Fish ◽  
And Migration

The role of the cell surface in the migration of primordial germ cells in early chick embryos: effects of concanavalin A

Development ◽  
1978 ◽  
Vol 46 (1) ◽  
pp. 5-20
Author(s):  
H. Lee ◽  
N. Karasanyi ◽  
R. G. Nagele
Keyword(s):  
Cell Surface ◽  
Germ Cells ◽  
Concanavalin A ◽  
Primordial Germ Cells ◽  
Sublethal Dose ◽  
Chick Embryos ◽  
Con A ◽  
And Migration ◽  
Coat Material

Effects of concanavalin A (Con A) on the morphology and migration of primordial germ cells (PGCs) in stage-6 to -12 chick embryos were investigated. Con A, at a sublethal dose (10µg/ml), inhibited migration of PGCs from the germinal crescent area to other parts of the embryo. Affected PGCs were more rounded without the usual cytoplasmic extensions, but the integrity of other structures was unaffected. Nearly identical results were obtained with another lectin, wheat germ agglutinin (10µg/ml). Histochemistry using Con A-horseradish peroxidase revealed that PGCs in control embryos had a thin, rather uniform layer of extracellular coat material (ECM). Con A appeared to alter the distribution of ECM on PGCs, i.e. some parts of the cell surface were devoid of any detectable ECM, while others had small, scattered patches of ECM. Con A effects were alleviated by α-methyl-d-mannoside. Overall results of the present study indicated that the observed inhibition of PGC migration in early chick embryos is a consequence of Con A-induced alterations of cell surface properties.

scholarly journals The Origin And Migration Of Primordial Germ Cells In Sturgeons

PLoS ONE ◽  
2014 ◽  
Vol 9 (2) ◽  
pp. e86861 ◽  
Author(s):  
Taiju Saito ◽  
Martin Pšenička ◽  
Rie Goto ◽  
Shinji Adachi ◽  
Kunio Inoue ◽  
...  
Keyword(s):  
Germ Cells ◽  
Primordial Germ Cells ◽  
And Migration

scholarly journals Origin and migration of primordial germ cells in mammals

1981 ◽  
Vol 4 (4) ◽  
pp. 333-362 ◽  
Author(s):  
E. M. Eddy ◽  
Judy M. Clark ◽  
Daniel Gong ◽  
Bruce A. Fenderson
Keyword(s):  
Germ Cells ◽  
Primordial Germ Cells ◽  
And Migration

scholarly journals Zebrafish Staufen1 and Staufen2 are required for the survival and migration of primordial germ cells

2006 ◽  
Vol 292 (2) ◽  
pp. 393-406 ◽  
Author(s):  
Srinivas Ramasamy ◽  
Hui Wang ◽  
Helen Ngoc Bao Quach ◽  
Karuna Sampath
Keyword(s):  
Germ Cells ◽  
Primordial Germ Cells ◽  
And Migration
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