Simultaneous Sequential Determination of Compounds of Toxicological Interest in Mixtures by Derivative Spectroscopy

1992 ◽  
Vol 16 (4) ◽  
pp. 240-243 ◽  
Author(s):  
A. Cruz ◽  
M. Lopez-Rivadulla ◽  
P. Fernandez ◽  
A.M. Bermejo
Keyword(s):  
Sequential Determination ◽  
Derivative Spectroscopy

Development and Validation of Derivative Spectroscopic Method for Simultaneous Estimation of Cefadroxil and Probenecid

2014 ◽  
Vol 7 (1) ◽  
pp. 2350-2355
Author(s):  
Pratik S Mehta ◽  
Pratik R. Patel ◽  
Rajesh R Parmar ◽  
M M K Modasiya ◽  
Dushyant A Shah
Keyword(s):  
Spectroscopic Method ◽  
Spectral Interference ◽  
Synthetic Mixture ◽  
Simultaneous Estimation ◽  
Zero Crossing ◽  
First Order ◽  
Derivative Spectroscopy ◽  
Development And Validation ◽  
Crossing Point

A novel, simple, accurate, sensitive, precise and economical derivative spectroscopic method was developed and validated for the determination of cefadroxil and probenecid in synthetic mixture. First order derivative spectroscopy method was adopted to eliminate spectral interference. The method obeys Beer’s Law in concentration ranges of 4-36 μg/ml for cefadroxil and of 5-25 μg/ml of probenecid. The zero crossing point for cefadroxil and probenecid was 260 nm and 237.8 nm respectively in 0.1N HCl. The method was validated in terms of accuracy, precision, linearity, limits of detection, limits of quantitation. This method has been successively applied to synthetic mixture and no interference from the synthetic mixture’s excipients was found.   

scholarly journals Sequential determination of chromium(VI) and chromium(III) by potentiometric flow-injection method.

2000 ◽  
Vol 49 (1) ◽  
pp. 59-64 ◽  
Author(s):  
Hiroki OHURA ◽  
Toshihiko IMATO ◽  
Ikuo MATSUO ◽  
Sumio YAMASAKI
Keyword(s):  
Flow Injection ◽  
Injection Method ◽  
Sequential Determination ◽  
Chromium Vi

A Rapid, Simultaneous Determination of Paraquat and Diquat in Serum and Urine Using Second-Derivative Spectroscopy

1992 ◽  
Vol 16 (4) ◽  
pp. 214-216 ◽  
Author(s):  
Chiaki Fuke ◽  
Kiyoshi Ameno ◽  
Setsuko Ameno ◽  
Takahiro Kirlu ◽  
Toyohiko Shinohara ◽  
...  
Keyword(s):  
Simultaneous Determination ◽  
Second Derivative ◽  
Derivative Spectroscopy ◽  
Second Derivative Spectroscopy ◽  
Serum And Urine

scholarly journals Flow injection analysis of water. Part 1: Automatic preconcentration determination of sulphate, ammonia and iron(II)/iron(III)

1993 ◽  
Vol 15 (4) ◽  
pp. 141-146 ◽  
Author(s):  
J. S. Cosano ◽  
M. D. Luque de Castro ◽  
M. Valcárcel
Keyword(s):  
Flow Injection ◽  
Good Reproducibility ◽  
Chemical Systems ◽  
Sequential Determination ◽  
On Line ◽  
Exchange Material ◽  
Iron Complexation ◽  
Simple Flow ◽  
Ammonia Formation

This paper describes a simple flow-injection (FI) manifold for the determination of a variety of species in industrial water. The chemical systems involved in the determination of ammonia (formation of Indophenol Blue), sulfate (precipitation with Ba(II)), and iron (complexation with 1,10-phenanthroline with the help of a prior redox reaction for speciation) were selected so that a common manifold could be used for the sequential determination of batches of each analyte. A microcolumn of a suitable ion exchange material was used for on-line preconcentration of each analyte prior to injection; linear ranges for the determination of the analytes at the ng/ml levels were obtained with good reproducibility. The manifold and methods are ready for full automation.

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