scholarly journals Embryonal carcinoma of an intraabdominal testicular tumor on an undescended testicle: a case report

2020 ◽  
Author(s):  
Mihai Domnutiu Suciu ◽  
Nucu Alexandru Marica ◽  
Traian Oniu ◽  
Andrei Ionut Tomuta ◽  
Radu Badea
Keyword(s):  
High Risk ◽  
Embryonal Carcinoma ◽  
Testicular Tumor ◽  
Surgical Excision ◽  
Testicular Tumors ◽  
Retroperitoneal Lymphadenectomy ◽  
Left Testicle ◽  
Lymphnode Metastasis ◽  
Risk Of Malignancy ◽  
Histological Result

Cryptorchidism, as a singular pathology or associated with other dysgenesis syndromes, is one of the main factors of risk for the development of the testicular tumors. Although there are a great number of cases of undescended testicles that are diagnosed and treated during the first 6-12 months of life, there are rare cases of adults who are undiagnosed and untreated from this anomaly, which can present a high risk of malignancy . In this study we present the case of a 36-year-old patient, diagnosed at puberty with left cryptorchidism, untreated, who also hadevidenced a large intraabdominal tumoral mass associated with it. The tumoral mass had its origin in the undescended left testicle. Surgical excision of the tumor and retroperitoneal lymphadenectomy was performed. The histological result revealed embryonal carcinoma, without lymphnode metastasis. Adult patients with untreated cryptorchidism should be thoroughly investigated, as they have a high risk of developing testicular cancer.

Report on 8 Cases of Testicular Tumors in Childhood.

1974 ◽  
Vol 60 (2) ◽  
pp. 157-162 ◽  
Author(s):  
Giorgio Pizzocaro ◽  
Fulvio Zanoni
Keyword(s):  
Embryonal Carcinoma ◽  
Alkylating Agents ◽  
Retroperitoneal Lymph Node Dissection ◽  
Retroperitoneal Lymph Node ◽  
Tunica Vaginalis ◽  
Testicular Tumors ◽  
Retroperitoneal Lymphadenectomy ◽  
Radical Orchiectomy ◽  
Pure Seminoma ◽  
In Infants And Children

Since 1944, 8 patients under 15 years of age have been hospitalized at the National Cancer Institute in Milano for testicular neoplasms, that is 2 % of all cases. Four were embryonal carcinomas (pure or with associated teratoma and choriocarcinoma), and two were rhabdomyosarcomas. Only one case of seminoma and one case of benign mesothelioma of the tunica vaginalis propria of testis were described. Embryonal carcinoma and rhabdomyosarcoma in infants and children should be managed by radical orchiectomy and bilateral retroperitoneal lymphadenectomy. Inoperable cases have a very poor prognosis and adequate chemotherapy may prolong survival. Pure seminoma should be treated by radical orchiectomy and radiotherapy on the lymph-nodes as indicated by the extent of the disease. In advanced cases, alkylating agents are very useful. Mesotheliomas are not true testicular tumors, as they arise from the tunica vaginalis propria of testis. They may be benign or malignant. In benign cases orchiectomy alone is sufficient for cure, whereas in malignant instances bilateral retroperitoneal lymph-node dissection in mandatory.

scholarly journals Seminoma in Undescended Intra Abdominal Testis: A Case Report

1970 ◽  
Vol 18 (2) ◽  
pp. 131-133 ◽  
Author(s):  
MM Haque ◽  
AB Siddique ◽  
ABMG Rabbani ◽  
MA Quasem ◽  
AKMG Rahman ◽  
...  
Keyword(s):  
Case Report ◽  
High Risk ◽  
Testicular Tumor ◽  
Early Age ◽  
Sexually Active ◽  
Lower Abdomen ◽  
Undescended Testes ◽  
Cryptorchid Testis ◽  
Risk Of Cancer ◽  
Abdominal Testis

A mass in the lower abdomen in a sexually active man with a cryptorchid testis strongly points towards the diagnosis of malignancy in the abdominal testis.1 The incidence of testicular tumor is 11 times more in inguinal testes and 50 times more in intra abdominal testes. 2 Normally, the testes, which are inside the abdomen during gestation, migrate into the scrotum by the time of birth. Occasionally, boys are born with testes that are still in the abdomen or in the groin, not having completed their journey to the scrotum. These undescended testes are at high risk of cancer and should be moved into the scrotum at an early age or removed entirely.   doi: 10.3329/taj.v18i2.3194 TAJ 2005; 18(2): 131-133

Brain metastasis from germinal tumors of the testis

1998 ◽  
Vol 88 (4) ◽  
pp. 761-763 ◽  
Author(s):  
Seiichi Yoshida ◽  
Ken Morii
Keyword(s):  
Brain Metastasis ◽  
Testicular Tumor ◽  
Lung Tumors ◽  
Surgical Removal ◽  
Cerebellar Tumor ◽  
Content Type ◽  
Left Testicle ◽  
Nonseminomatous Germ Cell Tumor ◽  
Large Brain ◽  
The Brain

✓ Brain metastasis in patients with disseminated nonseminomatous germ cell tumor (NSGCT) has been considered to occur rarely. The authors present the case of a 43-year-old man with an enlarged left testicle, a palpable inguinal tumor, multiple lung tumors, and a large cerebellar tumor. In separate operations, performed 1 month apart, the large cerebellar tumor and the testicular tumor were excised. Elements of teratocarcinoma, embryonal carcinoma, and choriocarcinoma were present in both the brain and testicular tumors. After chemotherapy in which bleomycin, etoposide, and cisplatin were used, the lung tumors and also the surrounding metastasis disappeared; the patient now leads a useful life and remains free from cancer in all organs. The authors suggest that surgical removal of tumor before initiating radiotherapy and chemotherapy for large brain metastasis from NSGCT will produce better results than using the nonsurgical treatments alone.

scholarly journals An 81-year-old patient with recent diagnosis of classic testicular seminoma

2016 ◽  
Vol 10 (2) ◽  
pp. 143
Author(s):  
Sandro José Martins ◽  
José Carlos De Almeida ◽  
Vitorino Modesto Dos Santos ◽  
Ana Carolina Vieira Cançado ◽  
Giovanna Ferraz Cavalcanti ◽  
...  
Keyword(s):  
Early Stage ◽  
Testicular Tumor ◽  
Population Based ◽  
Medical Attention ◽  
Left Testis ◽  
Testicular Seminoma ◽  
Left Testicle ◽  
First Choice ◽  
Recent Diagnosis ◽  
Radical Orchiectomy

An old patient with recent diagnosis of classic seminoma is reported. The tumor of left testicle was heralded by tenderness about 30 days before medical attention and enlarged testis confirmation. There was antecedent of left testis hypotrophy treated with testosterone and a surgery for varicocele at 15 years of age. Clinical hypothesis of testicular tumor was strengthened by ultrasonography images and elevated tumor markers (lactate dehydrogenase, <span>α</span>-fetoprotein, and <span>β</span>-hCG). Radical orchiectomy was performed and a classic seminoma (pT1pNx) was diagnosed. Active waiting was the first choice for management, but six months later a retroperitoneal mass with lymph node enlargement were found, and he underwent four sessions of carboplatin (AUC 5), bleomycin and etoposide (BEP regimen). Asymptomatic, he was referred to outpatient surveillance on Oncology. Population-based studies about frequency and outcome of early-stage testis seminoma in elderly are scarce. Case studies might contribute to the knowledge about this condition.

scholarly journals Dermatofibrosarcoma Protuberans: Retrospective Single Center Analysis Over 16 Years

2018 ◽  
Vol 6 (1) ◽  
pp. 35-37
Author(s):  
Uwe Wollina ◽  
Dana Langner ◽  
Jacqueline Schönlebe ◽  
Katlein França ◽  
Torello Lotti ◽  
...  
Keyword(s):  
Prognostic Factors ◽  
High Risk ◽  
Local Recurrence ◽  
Three Dimensional ◽  
Dermatofibrosarcoma Protuberans ◽  
Surgical Excision ◽  
Metastatic Spread ◽  
Single Center ◽  
Emerging Treatments ◽  
Margin Control

Dermatofibrosarcoma protuberans (DFSP) is rare mesenchymal neoplasia with a high risk of local recurrence but a low risk of metastatic spread. Tumor cells express CD34 and show a characteristic translocation t(17;22)(q22;q13). We analysed the documented cases at the Department of Dermatology and Allergology between 08/2001 and 08/2017. The diagnosis had been confirmed by histology and immunohistology in all cases. We identified four adults and a pediatric patient with DFSP. All patients were treated by wide surgical excision and controlled by three-dimensional histologic margin control. We observed no recurrence and no metastatic spread. We discuss prognostic factors and emerging treatments.

High-Risk Lesions Detected by MRI-Guided Core Biopsy: Upgrade Rates at Surgical Excision and Implications for Management

2021 ◽  
Vol 216 (3) ◽  
pp. 622-632
Author(s):  
Aya Y. Michaels ◽  
Paula S. Ginter ◽  
Katerina Dodelzon ◽  
Matthew R. Naunheim ◽  
Genevieve N. Abbey
Keyword(s):  
High Risk ◽  
Core Biopsy ◽  
Surgical Excision ◽  
Mri Guided
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