scholarly journals Long-Term Growth and Body Composition Consequences of Using Fortified Donor Milk or Preterm Formula for Very-Low-Birth-Weight Infants

2019 ◽  
Author(s):  
Steven A Abrams
Author(s):  
Kousiki Patra ◽  
Michelle M. Greene ◽  
Grace Tobin ◽  
Gina Casini ◽  
Anita L. Esquerra-Zwiers ◽  
...  

Objective This study was aimed to evaluate the impact of donor milk (DM) received in the first 28 days of life (DOL) on neurodevelopmental (ND) outcome at 20-month corrected age (CA) in very low birth weight (VLBW) infants. Study Design A total of 84 infants born in 2011 to 2012 who received only mother's own milk (MOM) and/or preterm formula (PF) was compared with 69 infants born in 2013 to 2014 who received MOM and/or DM. Daily enteral intake of MOM, DM, and PF was collected through 28 DOL. ND outcomes were assessed with the Bayley-III. Multiple regression analyses were adjusted for the effect of social and neonatal risk factors, alongside era of birth on ND outcome. Results Infants exposed to DM were born to older mothers (p < 0.01) and had higher incidence of severe brain injury (p = 0.013). Although DM group infants received first feed at earlier DOL (p < 0.001), there were no differences in MOM intake at DOL 14 or 28 between the two groups. In regression analyses, DM group did not predict 20-month ND outcome. Conclusion There were no differences in ND outcome between infants born before and after the introduction of DM. This may have been due to the similar percent of MOM at DOL 14 and 28 in the two eras. Key Points


Author(s):  
Kousiki Patra ◽  
Michelle M. Greene ◽  
Grace Tobin ◽  
Gina Casini ◽  
Anita L. Esquerra-Zwiers ◽  
...  

PEDIATRICS ◽  
1992 ◽  
Vol 89 (2) ◽  
pp. 357-357
Author(s):  
HELEN HARRISON

To the Editor.— The authors of the National Institute of Child Health and Human Development report on neonatal care1 found "important" variations among neonatal intensive care units in philosophies of treatment, methods of treatment, and short-term outcomes. In a recent meta-analysis of follow-up studies,2 researchers document a similarly haphazard approach to the long-term evaluation of very low birth weight survivors. Until randomized controlled clinical trials validate the safety and efficacy of neonatal therapies, and until long-term outcomes are assessed accurately, the treatment of very low birth weight infants should be declared experimental.


1995 ◽  
Vol 14 (5) ◽  
pp. 455-462 ◽  
Author(s):  
C H Gilmour ◽  
J M Sentipal-Walerius ◽  
J G Jones ◽  
J M Doyle ◽  
B S Brozanski ◽  
...  

2020 ◽  
Vol 63 (8) ◽  
pp. 284-290 ◽  
Author(s):  
Jang Hoon Lee ◽  
YoungAh Youn ◽  
Yun Sil Chang ◽  

Korea currently has the world’s lowest birth rate but a rapidly inreasing number of preterm infants. The Korean Neonatal Network (KNN), launched by the Korean Society of Neonatology under the support of Korea Centers for Disease Control, has collected population-based data for very low birth weight infants (VLBWIs) born in Korea since 2013. In terms of the short-term outcomes of VLBWIs born from 2013 to 2016 registered in the KNN, the survival rate of all VLBWIs was 86%. Respiratory distress syndrome and bronchopulmonary dysplasia were observed in 78% and 30% of all VLBWIs, respectively. Necrotizing enterocolitis occurred in 7%, while 8% of the VLBWIs needed therapy for retinopathy of prematurity in the neonatal intensive care unit (NICU). Sepsis occurred in 21% during their NICU stay. Intraventricular hemorrhage (grade ≥III) was diagnosed in 10%. In terms of the long-term outcomes for VLBWIs born from 2013 to 2014 registered in the KNN, the post-discharge mortality rate was approximately 1.2%–1.5%, mainly owing to their underlying illness. Nearly half of the VLBWIs were readmitted to the hospital at least once in their first 1–2 years of life, mostly as a result of respiratory diseases. The overall prevalence of cerebral palsy was 6.2%–6.6% in Korea. Bilateral blindness was reported in 0.2%–0.3% of VLBWIs, while bilateral hearing loss was found in 0.8%–1.9%. Since its establishment, the KNN has published annual reports and papers that facilitate the improvement of VLBWI outcome and the formulation of essential healthcare policies in Korea.


2011 ◽  
Vol 10 (1) ◽  
Author(s):  
Juan Antonio Costa-Orvay ◽  
Josep Figueras-Aloy ◽  
Gerardo Romera ◽  
Ricardo Closa-Monasterolo ◽  
Xavier Carbonell-Estrany

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