Efficacy of Screening Breast MRI for High-Risk Women

Author(s):  
Christoph I. Lee

This chapter, found in the cancer screening and management section of the book, provides a succinct synopsis of a key study examining the efficacy of screening breast magnetic resonance imaging (MRI) for high-risk women. This summary outlines the study methodology and design, major results, limitations and criticisms, related studies and additional information, and clinical implications. Breast MRI screening has higher sensitivity than mammography for high-risk women, but both the specificity and positive predictive value are lower than for mammography screening. In addition to outlining the most salient features of the study, a clinical vignette and imaging example are included in order to provide relevant clinical context.

2016 ◽  
Vol 121 (8) ◽  
pp. 611-617 ◽  
Author(s):  
Paola Clauser ◽  
Enrico Cassano ◽  
Arianna De Nicolò ◽  
Anna Rotili ◽  
Bernardo Bonanni ◽  
...  

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Marco Gierlinger ◽  
Dinah M. Brandner ◽  
Bernhard G. Zagar

Abstract The multi-seed region growing (MSRG) algorithm from previous work is extended to extract elongated segments from breast Magnetic Resonance Imaging (MRI) stacks. A model is created to adjust the MSRG parameters such that the elongated segments may reveal vessels that can support clinicians in their diagnosis of diseases or provide them with useful information before surgery during e. g. a neoadjuvant therapy. The model is a pipeline of tasks and contains user-defined parameters that influence the segmentation result. A crucial task of the model relies on a skeletonization-like algorithm that collects useful information about the segments’ thickness, length, etc. Length, thickness, and gradient information of the pixel intensity along the segment helps to determine whether the extracted segments have a tubular structure, which is assumed to be the case for vessels. In this work, we show how the results are derived and that the MSRG algorithm is capable of extracting vessel-like segments even from noisy MR images.


2021 ◽  
Vol 54 (2) ◽  
pp. 83-86
Author(s):  
Samuel Silva Ferreira ◽  
Adriene Moraes Campos ◽  
Patrícia Lima Fernandes ◽  
Izabela Machado Pereira ◽  
Flavia Maria Rodrigues ◽  
...  

Abstract Objective: To describe the indications for breast magnetic resonance imaging (MRI) at a referral center for breast cancer in Brazil. Materials and Methods: This was a retrospective study in which we reviewed the clinical records, including physician requests and patient questionnaires, of women who underwent breast MRI between 2014 and 2018 at a referral center for the diagnosis and treatment of breast cancer in the city of Belo Horizonte, Brazil. Results: The most common indication for breast MRI was as a complement to mammography/ultrasonography (in 43.6% of cases), followed by breast cancer staging (in 25.1%), the screening of patients at high risk (in 17.4%), the evaluation of breast implants (in 10.1%), and the evaluation of the response to neoadjuvant chemotherapy (in 3.8%). Conclusion: Although there is strong evidence supporting the use of breast MRI, mainly for the screening of high-risk patients, the imaging method is underutilized in Brazil.


2011 ◽  
Vol 62 (1) ◽  
pp. 22-30 ◽  
Author(s):  
Neety Panu ◽  
Elizabeth Morris

Advances made since the first application of breast magnetic resonance imaging (MRI) in the late 1980s have made it an integral complement to a comprehensive breast assessment centre. Incorporating breast MRI into an existing practice can appear daunting, but a structured and organized approach allows for a smoother transition. With a well thought out plan that engages all team members and experience in interpretation and performing of interventional procedures, breast MRI will serve to add valuable information in patient management.


Author(s):  
Janice Hui Ling Goh ◽  
Toh Leong Tan ◽  
Suraya Aziz ◽  
Iqbal Hussain Rizuana

Digital breast tomosynthesis (DBT) is a fairly recent breast imaging technique invented to overcome the challenges of overlapping breast tissue. Ultrasonography (USG) was used as a complementary tool to DBT for the purpose of this study. Nonetheless, breast magnetic resonance imaging (MRI) remains the most sensitive tool to detect breast lesion. The purpose of this study was to evaluate diagnostic performance of DBT, with and without USG, versus breast MRI in correlation to histopathological examination (HPE). This was a retrospective study in a university hospital over a duration of 24 months. Findings were acquired from a formal report and were correlated with HPE. The sensitivity of DBT with or without USG was lower than MRI. However, the accuracy, specificity and PPV were raised with the aid of USG to equivalent or better than MRI. These three modalities showed statistically significant in correlation with HPE (p < 0.005, chi-squared). Generally, DBT alone has lower sensitivity as compared to MRI. However, it is reassuring that DBT + USG could significantly improve diagnostic performance to that comparable to MRI. In conclusion, results of this study are vital to centers which do not have MRI, as complementary ultrasound can accentuate diagnostic performance of DBT.


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