Female Sexual Biochemistry (DRAFT)

2018 ◽  
Author(s):  
Madeleine M. Castellanos
Keyword(s):  
Female Sexuality ◽  
Reproductive Organs ◽  
Environmental Toxins ◽  
Sexual Response ◽  
Hormone Activity ◽  
The Central Nervous System ◽  
Sexual Response Cycle ◽  
Synthetic Hormones ◽  
Changes In Pregnancy ◽  
Dual Control Model

“Female Sexual Biochemistry” reviews the key hormones and neurotransmitters that have a major role in female sexuality. Estrogens—estradiol, estrone, and estriol—as well as major androgens, such as testosterone and dihydrotestosterone (DHT), are presented with a discussion of their role in the support of the reproductive organs and genitals as well as their actions on the central nervous system to affect sexual desire, arousal, and responsiveness. The interaction and regulation of estrogen by progesterone and thyroid hormone is included. A review of the dual-control model of sexual responsiveness is presented, including excitatory and inhibitory factors, as well as a summary of major neurotransmitters that work to enhance sexual arousal or inhibit it. The sexual response cycle is reviewed and relevant changes in pregnancy, childbirth, perimenopause, and menopause are presented. Finally, there is mention of how synthetic hormones and environmental toxins with hormone activity may alter a woman’s sexual response.

Serial neurochemical measurement of cerebrospinal fluid during the human sexual response cycle

2006 ◽  
Vol 24 (12) ◽  
pp. 3445-3452 ◽  
Author(s):  
Tillmann H. C. Krüger ◽  
Boris Schiffer ◽  
Matthias Eikermann ◽  
Philip Haake ◽  
Elke Gizewski ◽  
...  
Keyword(s):  
Cerebrospinal Fluid ◽  
Sexual Response ◽  
Sexual Response Cycle

4. UNDERSTANDING VENUS: EXPLORING FEMALE DESIRE

Sexual Health ◽  
2007 ◽  
Vol 4 (4) ◽  
pp. 285
Author(s):  
P. Weerakoon
Keyword(s):  
Sexual Desire ◽  
Best Practice ◽  
Female Sexuality ◽  
Functional Brain Imaging ◽  
Sexual Response ◽  
Female Desire ◽  
The Road ◽  
On The Road ◽  
Female Sexual Response

The female sexual response is highly variable and multifaceted and is a result of interplay of physiological, psychological and interpersonal factors. The advent of technology and non-invasive functional brain imaging has provided a map of the regions of the brain involved in sexual arousal and the neurochemistry that underlies the process. However, this increase in the understanding of the biological basis of female sexuality has only reinforced the role of interpersonal and cultural factor in the sexual response, specially the genesis of sexual desire. An acceptance of this by professionals, has led to the consensus for a more holistic biopsychosocial approach for the management of female sexual concerns. The presentation will discuss the current research on the neural and hormonal basis for female desire and explore the role of sexual desire as a motivator and a force for sexual activity in the context of the prevailing models of the female sexual response. There is a need for the recognition of the place and value of sexual desire in the female sexual response and an appreciation that whereas there is a biological 'drive', this is tempered by the motivational aspect (individual and relationship psychology) and the cultural and moral overlay of values and attitudes. This will in turn provide the milieu for understanding normal and dysfunctional sexual desire and assist us on the road to discovering a best practice model for the diagnosis and management of 'female desire disorders'.

Preliminary Evidence on How the Dual Control Model Predicts Female Sexual Response to a Bogus Negative Feedback

2020 ◽  
pp. 003329412090731
Author(s):  
Reina Granados ◽  
Joana Carvalho ◽  
Juan Carlos Sierra
Keyword(s):  
Sexual Arousal ◽  
Negative Feedback ◽  
Control Model ◽  
Sexual Response ◽  
Dual Control ◽  
Sexual Performance ◽  
Sexual Excitation ◽  
Subjective Sexual Arousal ◽  
Sexual Responses ◽  
Dual Control Model

The Dual Control Model of sexual response has been mostly tested with men. As such, there is a lack of evidence on how such model applies to women’s experience of sexual arousal, particularly when they face a threatening situation such as the threat of sexual performance failure. The aim of the current study was to test whether the Dual Control Model dimensions predict women’s sexual responses to a bogus negative feedback about their sexual performance. In addition, 22 women were exposed to a sexually explicit film clip, while their genital arousal was being measured. During this presentation, a bogus negative feedback, aimed at increasing women’s anxiety about their sexual performance, was provided. Vaginal photopletismography and self-report questions were used as means to evaluate women’s genital and subjective sexual arousal, respectively. The Sexual Excitation/Sexual Inhibition Inventory for Women was further used to capture women’s sexual dynamics. Regression analysis on the high-order factors revealed that sexual excitation proneness was the only predictor of the subjective sexual responses, while none of the factors has predicted genital arousal. “Arousability” and “Concerns about sexual function” dimensions predicted subjective sexual arousal. Sexual arousability may prevent women of lowering their subjective sexual responses in a sexually demanding situation, while “Concerns about sexual function” may have the opposite role, thus being a target of clinical interest. This work provides new data on the Dual Control Model of sexual response, and particularly on its role in women’s sexual functioning.

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