Treatment of Men With Erectile Dysfunction With Transurethral Alprostadil

Author(s):  
Joshua Bodie

This chapter summarizes the results of an important trial comparing transurethral alprostadil to placebo in men with erectile dysfunction. Sexual intercourse was reported as having occurred more often in the alprostadil group, and more men in the group experienced orgasm. Penile pain was reported by approximately one-third of men during clinic testing. This study described the initial experience with transurethral alprostadil and identified the effectiveness of patient-specific doses.

2011 ◽  
Vol 8 (3) ◽  
pp. 211-211 ◽  
Author(s):  
S.-I. Hisasue ◽  
H. Ide ◽  
T. China ◽  
S. Isotani ◽  
S. Muto ◽  
...  

2013 ◽  
Vol 1 (2) ◽  
Author(s):  
Andre Hutagalung ◽  
Christoffel Elim ◽  
Herdy Munayang

Abstract: Normal sexual function is a bio-psycho-social process which is significantly related to the quality of life (QOL). Any disturbance in one of the components can be a disaster in sexual life.  Erectile dysfunction is a disability to get an erection or to maintain the erection well enough for a sexual intercourse, which persists or recurs at least three months conse-cutively due to either psychogenic or organic disturbances, or both. Some psychogenic dis-turbances especially depression, anxiety, and relational distress, play some important roles in ED. Besides that, aging, low testoteron level, physical diseases, and some certain medicines have to be included. Key words: erection, erectile dysfunction, sexual stimulus, depression.     Abstract: Fungsi seksual yang normal merupakan suatu proses biopsikososial yang berkaitan langsung dengan kualitas hidup. Adanya gangguan pada salah satu komponen dapat menjadi malapetaka bagi kehidupan seksual. Disfungsi ereksi dapat dedefinisikan sebagai suatu keti-dakmampuan untuk ereksi atau mempertahankan ereksi yang cukup untuk melakukan hu-bungan seksual yang memuaskan, yang menetap atau berulang paling tidak selama tiga bulan berturut-turut. Gangguan psikogenik khususnya sindroma depresi, ankietas, dan distres relasional berperan penting dalam hal terjadinya disfungsi ereksi. Disamping itu usia lanjut, rendahnya kadar testoteron, penyakit fisik, dan beberapa jenis obat perlu diperhitungkan. Kata kunci: fisiologi ereksi, disfungsi ereksi, stimulus seksual, depresi.


2010 ◽  
Vol 37 (6Part19) ◽  
pp. 3240-3240
Author(s):  
S Qi ◽  
A Hu ◽  
D Westerly ◽  
H Rice ◽  
F Newman ◽  
...  

2016 ◽  
Vol 12 (4) ◽  
pp. 297-304 ◽  
Author(s):  
Maria Voznesensky ◽  
Kiran Annam ◽  
Karl J. Kreder

Cancer can cause sexual adverse effects by direct and indirect pathways. It can involve sexual organs, indirectly affect body image, or cause fatigue or depression with subsequent effects on libido. Erectile dysfunction (ED), the inability to obtain or maintain an erection firm enough for sexual intercourse, can also result from adverse effects of cancer treatment, such as fatigue, pain, or anxiety about therapy. In addition, depressed feelings about having cancer can affect sexuality, causing a range of signs and symptoms that can lead to ED. Chemotherapy, hormone therapy, surgery, and radiation can all cause sexual adverse effects. Additional factors that play a role include patient age and degree of ED before starting cancer treatment. In this article, we discuss how chemotherapy, hormone therapy, surgery, and radiation affect erectile function as well as possible treatment options for ED.


2001 ◽  
Vol 27 (5) ◽  
pp. 475-482 ◽  
Author(s):  
A. Faix ◽  
J. F. Lapray ◽  
C. Courtieu ◽  
A. Maubon ◽  
Kerry Lanfrey

2013 ◽  
Vol 106 ◽  
pp. S432-S433
Author(s):  
F. Lliso ◽  
M.C. Pujades ◽  
T. Garcia ◽  
J. Gimeno ◽  
V. Carmona ◽  
...  

2017 ◽  
Vol 104 (1) ◽  
pp. 336-341 ◽  
Author(s):  
Liesbeth M. Desender ◽  
Isabelle Van Herzeele ◽  
Zoran Rancic ◽  
Colin Bicknell ◽  
Ignatios Zairis ◽  
...  

2017 ◽  
Vol 85 (2) ◽  
pp. 55-59 ◽  
Author(s):  
Pier Andrea Della Camera ◽  
Simone Morselli ◽  
Gianmartin Cito ◽  
Giovanni Tasso ◽  
Nicola Laruccia ◽  
...  

Objective: The aim of the study is the evaluation of the efficacy and safety of the treatment with topical alprostadil (Vitaros©) in post-robot assisted radical prostatectomy (RARP) rehabilitation therapy of patients with erectile dysfunction (ED). Methods: Seventy-four patients were enrolled and underwent non-nerve-sparing RARP. Inclusion criteria: age <75, preoperatively International Index of Erectile Function (IIEF-5) >16, erection hardness score (EHS) ⩾2, weekly sexual intercourse ⩾1, affirmative answers to Sexual Encounter Profile Question (SEP-Q) 2 and SEP-Q3, Charlson Comorbidity Index (CCI) ⩽5, Eastern Cooperative Oncology Group (ECOG) performance status ⩽1, no moderate/severe cardiovascular disease. Results: Vitaros was administered ⩾2 twice a week. At month 6, the IIEF-5 decreased from 20.5 preoperative to 18.1 post-treatment. EHS score decreased from a mean of 3.3 to a mean of 3.0. The quality of life score decreased from an average of 5.1 to 2.3. Weekly sexual intercourse decreased from an average of 2.1 to 1.7. Six patients dropped out; 89.7% patients showed a positive SEP-Q2 and 77.8% a positive SEP-Q3. All patients responded positively to Global Assessment Questions (GAQ)-1 and 97% to GAQ-2. Of all 68 analyzed patients, 13 (17.6%) switched to intracavernous injection therapy. Conclusions: In conclusion, Vitaros may become a viable alternative to common injective therapies in well-selected patients after RARP.


2020 ◽  
Vol 17 (6) ◽  
pp. S159
Author(s):  
F. Migliorini ◽  
A. Marcer ◽  
M.F. Lorenzo Gomez ◽  
F. Ribichini ◽  
A.B. Porcaro ◽  
...  

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