Repetitive Behaviors in Individuals with Autism Spectrum Disorders

2011 ◽  
pp. 200-212 ◽  
Author(s):  
James W. Bodfish
Keyword(s):  
Autism Spectrum Disorders ◽  
Autism Spectrum ◽  
Repetitive Behaviors ◽  
Spectrum Disorders

scholarly journals Restricted and Repetitive Behaviors as Predictors of Outcome in Autism Spectrum Disorders

2015 ◽  
Vol 46 (4) ◽  
pp. 1282-1296 ◽  
Author(s):  
Eva Troyb ◽  
Kelley Knoch ◽  
Lauren Herlihy ◽  
Michael C. Stevens ◽  
Chi-Ming Chen ◽  
...  
Keyword(s):  
Autism Spectrum Disorders ◽  
Autism Spectrum ◽  
Repetitive Behaviors ◽  
Predictors Of Outcome ◽  
Restricted And Repetitive Behaviors ◽  
Spectrum Disorders

scholarly journals SOCIAL STATUS AND GUT MICROBIAL DYSBIOSIS IN ADULTS AND CHILDREN WITH AUTISM SPECTRUM DISORDERS: A PROFOUND REVIEW OF THE AVAILABLE LITERATURE SOURCES

2021 ◽  
Vol 27 (3) ◽  
pp. 3939-3946
Author(s):  
Sevginar Ibryamova ◽  
◽  
Veselin Petkov ◽  
Tsveteslava Ignatova-Ivanova ◽  
Georgi Kolev ◽  
...  
Keyword(s):  
Autism Spectrum Disorders ◽  
Behavioral Problems ◽  
Autism Spectrum ◽  
Repetitive Behaviors ◽  
Diagnostic Methods ◽  
Restricted Interests ◽  
Microbial Dysbiosis ◽  
Gastrointestinal Problems ◽  
Adults And Children ◽  
Spectrum Disorders

Autism is a complex disorder without a specific diagnosis, so the disease is defined by its specific characteristics described in the literature as cognitive defects, social, communication and behavioral problems, repetitive behaviors, unusual sensitivity to stimuli such as noise, restricted interests, and self stimulation. There are many models in the literature explaining the biology of autism, which are based on genetics, immunity, various environmental factors and diet. There is a lot of literature data that people with Autism Spectrum Disorders (ASD) often have gastrointestinal problems that also affect their behavior. ASD suffer developmental disabilities from an early age, which can be both physical and psychological. Often people suffer these problems even throughout their lives. This review aims to provide basic information on definitions, historical data, diagnostic methods, behavioral etiology, gastrointestinal and social problems in adults and children with ASD.

scholarly journals Altered Intestinal Morphology and Microbiota Composition in the Autism Spectrum Disorders Associated SHANK3 Mouse Model

2019 ◽  
Vol 20 (9) ◽  
pp. 2134 ◽  
Author(s):  
Ann Katrin Sauer ◽  
Juergen Bockmann ◽  
Konrad Steinestel ◽  
Tobias M. Boeckers ◽  
Andreas M. Grabrucker
Keyword(s):  
Autism Spectrum Disorders ◽  
Inflammatory Responses ◽  
Autism Spectrum ◽  
Repetitive Behaviors ◽  
Intestinal Morphology ◽  
Microbiota Composition ◽  
Knock Out ◽  
E Coli ◽  
The Central Nervous System ◽  
Spectrum Disorders

Autism spectrum disorders (ASD) are a group of neurodevelopmental disorders characterized by deficits in social interaction and communication, and repetitive behaviors. In addition, co-morbidities such as gastro-intestinal problems have frequently been reported. Mutations and deletion of proteins of the SH3 and multiple ankyrin repeat domains (SHANK) gene-family were identified in patients with ASD, and Shank knock-out mouse models display autism-like phenotypes. SHANK3 proteins are not only expressed in the central nervous system (CNS). Here, we show expression in gastrointestinal (GI) epithelium and report a significantly different GI morphology in Shank3 knock-out (KO) mice. Further, we detected a significantly altered microbiota composition measured in feces of Shank3 KO mice that may contribute to inflammatory responses affecting brain development. In line with this, we found higher E. coli lipopolysaccharide levels in liver samples of Shank3 KO mice, and detected an increase in Interleukin-6 and activated astrocytes in Shank3 KO mice. We conclude that apart from its well-known role in the CNS, SHANK3 plays a specific role in the GI tract that may contribute to the ASD phenotype by extracerebral mechanisms.

scholarly journals Restricted and repetitive behaviors in autism spectrum disorders: The relationship of attention and motor deficits

2013 ◽  
Vol 25 (3) ◽  
pp. 773-784 ◽  
Author(s):  
Susan M. Ravizza ◽  
Marjorie Solomon ◽  
Richard B. Ivry ◽  
Cameron S. Carter
Keyword(s):  
Autism Spectrum Disorders ◽  
Motor Control ◽  
Motor System ◽  
Autism Spectrum ◽  
Repetitive Behaviors ◽  
Motor Deficits ◽  
Attentional Orienting ◽  
Restricted And Repetitive Behaviors ◽  
Spectrum Disorders ◽  
The Relationship

AbstractRestricted and repetitive behaviors (RRBs) are hallmark symptoms of autism spectrum disorders (ASDs); however, it has proven difficult to understand the mechanisms underlying these behaviors. One hypothesis suggests that RRBs are the result of a core deficit in attention. Alternatively, abnormalities of the motor system may constitute the central mechanism underlying RRBs, given motor deficits observed in ASDs. In this experiment, we investigated the etiology of RRBs and the relationship between attention and motor deficits. Movement impairments (a) may be indirectly related to attention deficits, (b) may result from a shared compromised process, or (c) may be independent. Twenty-two adolescents with ASD and 20 typically developing participants performed a spatial attention task. Movement impairments were assessed with a rhythmic tapping task. Attentional orienting and motor control were found to be related and supported the hypothesis that these impairments in ASD arise from a shared process. In contrast, measures of attention switching and motor control were found to be independent. Stereotyped behaviors, as assessed by parental ratings, were related more to the degree of motor impairment than to deficits of attention. These results suggest that both attentional orienting deficits and stereotyped RRBs are related to a compromised motor system.

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