The child with kidney disease

As adult nephrologists we recognize the importance of understanding the evolution of kidney disease in children and young adults. We also acknowledge that in many parts of the world there is no distinction between adult and paediatric nephrology and therefore it is important that nephrologists have a sound grasp of paediatric and adult kidney diseases. Transition from paediatric to adult nephrology services is a challenging time for many young adults living with kidney disease and ensuring adult nephrologists appreciate the multiple and often unique challenges growing up with kidney disease bring is an important component of nephrology practice. It is also important that as adult nephrologists we understand the spectrum of kidney diseases that affect children and young adults, which are often markedly different to those we encounter in adult practice.

Written for the busy nephrologist and internist who need easy to access information on the diagnosis, investigation, and treatment of patients with kidney disease, the Oxford Desk Reference Nephrology is presented in a way that is not only easy to read and digest but also is detailed enough to allow an in depth understanding of the complex mix of metabolic, immunological, and genetic causes of both acute and chronic kidney disease. The kidneys are rarely affected by disease in isolation; the book comprehensively covers the multisystem disorders that require a multidisciplinary approach, including the cardiological, rheumatological, haematological, infectious, oncological, and urological aspects of kidney disease. In parallel, it extensively describes the myriad multisystem complications of progressive chronic kidney disease with practical advice on how these should be investigated and managed. The importance of understanding the evolution of kidney disease in children and young adults is covered, as in many parts of the world there is no distinction between adult and paediatric nephrology. Therefore, it is important that nephrologists have a sound grasp of both paediatric and adult kidney diseases. The number of patients with advanced kidney disease treated with a kidney transplant or receiving dialysis is increasing in all parts of the world. All nephrologists will manage patients on dialysis or who have a kidney transplant and all internists will encounter these patients. Thus, it is imperative that they have an understanding of these treatments and the commonly encountered medical problems such patients experience.


2020 ◽  
Vol 31 (6) ◽  
pp. 1178-1190 ◽  
Author(s):  
Daniyal J. Jafree ◽  
David A. Long

The kidney contains a network of lymphatic vessels that clear fluid, small molecules, and cells from the renal interstitium. Through modulating immune responses and via crosstalk with surrounding renal cells, lymphatic vessels have been implicated in the progression and maintenance of kidney disease. In this Review, we provide an overview of the development, structure, and function of lymphatic vessels in the healthy adult kidney. We then highlight the contributions of lymphatic vessels to multiple forms of renal pathology, emphasizing CKD, transplant rejection, and polycystic kidney disease and discuss strategies to target renal lymphatics using genetic and pharmacologic approaches. Overall, we argue the case for lymphatics playing a fundamental role in renal physiology and pathology and treatments modulating these vessels having therapeutic potential across the spectrum of kidney disease.


2021 ◽  
Vol 9 (7) ◽  
pp. 1549-1554
Author(s):  
Kavita Rathore ◽  
Shamsa Fiaz

Introduction - Myopia is the most common Refractive error of the eye seen in children and young adults and it has become more prevalent in recent years and is a cause of concern the world over. Myopia commonly referred to as near or shortsightedness. Some of the clinical features of Vataja Timira can be correlated with Myopia. Timira is counted under the Drishtigata Rogas [1] described by Sushruta. Timira involving first and second patala in terms of symptoms, anatomical structures involved and the pathogenesis of the disease. Timira begins with the blurring of vision gradually leading to the deterioration of eyesight. Shastrokta lakshanas of Vatika Timira such as bhramantiva sa pashyati, aavil darshan, vyaavidha darshan, aruna darshan [2]. Materials and Methods - A 20-year-old male, came to Shalakya Tantra OPD in National Institute of Ayurveda, deemed to be University Jaipur (R.J.), with chief complaints of defective vision for distance in both eyes, pain in both eyes and watering from both eyes since 4 months. He was treated with Nasya, Netra Pariseka, one sitting of Tarpana, Triphala guggulu, Patoladi eyedrops and Netramritam eyedrops. Result - At the end of the study, improvement in the visual acuity in both eyes, improvement in pain in both eyes and watering from both eyes have reduced. Conclusion -Thus, it can be concluded that Ayurvedic treatments are helpful to control Myopia. Keywords: Myopia, Nasya, Tarpana, Netra pariseka, Timira, Triphala Guggulu.


1998 ◽  
Vol 4 (1) ◽  
pp. 10-16
Author(s):  
Gill Gorell Barnes

Family life in Britain is changing daily to include more stepfamilies, which have widely differing structures with varying histories, losses, transitions and economic circumstances. Of the one in five children who currently experience separation before they are 16, over half will live in a stepfamily at some point in their lives. Of the 150 000 couples with children who divorced each year at the end of the 1980s, a further 35 000 had a subsequent divorce. For some children we need to think of step-parenting within wider processes of transition, which include relationship changes of many kinds. The National Stepfamily Association have calculated that if current trends of divorce, cohabitation, remarriage and birth continue, there will be around 2.5 million children and young adults growing up in a stepfamily by the year 2000. The true pattern of re-ordering of partnership and family life is hard to chart, since many couples second or third time around prefer to cohabit rather than to marry.


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