Malignant tumours

2018 ◽  
pp. 474-477
Author(s):  
Cristina Basso ◽  
Peter T Buser ◽  
Stefania Rizzo ◽  
Massimo Lombardi ◽  
Gaetano Thiene
Keyword(s):  
Differential Diagnosis ◽  
Cardiovascular Magnetic Resonance ◽  
Magnetic Resonance ◽  
Late Enhancement ◽  
Cardiac Mass ◽  
Adult Patients ◽  
Malignant Tumours ◽  
Undifferentiated Pleomorphic Sarcoma ◽  
Pleomorphic Sarcoma

In adult patients, sarcomas are the most frequently encountered primary cardiac malignant tumours, followed by lymphomas. Primary sarcomas of the heart form a group of tumours with variable differentiation and cell pleomorphism. According to histopathology, they are categorized as angiosarcomas, leiomyosarcomas, undifferentiated pleomorphic sarcoma, and myxofibrosarcomas. On cardiovascular magnetic resonance (CMR), most sarcomas appear extremely heterogeneous and usually cannot be differentiated from each other. Some cases with angiosarcomas can be identified by their specific appearance with early- and late-enhancement CMR. Some features of early- and late-enhancement CMR may argue for lymphoma, when discussing the differential diagnosis of a malignant primary cardiac mass.

scholarly journals Undifferentiated pleomorphic sarcoma in oropharyngeal mucosa of patients with multiple basal cell carcinomas

Rare Tumors ◽  
2021 ◽  
Vol 13 ◽  
pp. 203636132110264
Author(s):  
Andrea Dekanić ◽  
Marko Velepič ◽  
Margita Belušić Gobić ◽  
Ita Hadžisejdić ◽  
Nives Jonjić
Keyword(s):  
Differential Diagnosis ◽  
Basal Cell ◽  
Polypoid Lesion ◽  
Older Patient ◽  
Mesenchymal Tumors ◽  
Undifferentiated Pleomorphic Sarcoma ◽  
Pleomorphic Sarcoma ◽  
Basal Cell Carcinomas ◽  
History Of ◽  
Multiple Basal Cell Carcinomas

Malignant mesenchymal tumors of oropharyngeal mucosa are rare. Those with fibroblastic and histiocytic differentiation in the skin are called atypical fibroxanthoma (AFX) and in the soft tissue undifferentiated pleomorphic sarcoma (UPS). Here we present a case of an older patient with a history of multiple basal cell carcinomas and recently with a rapidly growing polypoid lesion in the mucosa of posterior oropharyngeal wall with AFX/UPS morphology. The differential diagnosis, histological pitfalls of this poorly characterized mesenchymal lesions, and the challenges associated with treatment are discussed.

Malignant tumours, pericardial tumours, and therapy

ESC CardioMed ◽  
2018 ◽  
pp. 1617-1624
Author(s):  
Cristina Basso ◽  
Stefania Rizzo ◽  
Marialuisa Valente ◽  
Martina Perazzolo Marra ◽  
Gaetano Thiene
Keyword(s):  
Malignant Neoplasms ◽  
Malignant Tumours ◽  
Undifferentiated Pleomorphic Sarcoma ◽  
Cardiac Tumours ◽  
Pleomorphic Sarcoma

Primary malignant neoplasms account for 10% of all primary cardiac tumours and are represented by sarcomas (mainly angiosarcoma, undifferentiated pleomorphic sarcoma, leiomyosarcoma) and primary lymphomas. They usually infiltrate the cardiac walls, but may be also solely intracavitary, mimicking myxoma.

CMR approach in cardiac tumours

2018 ◽  
pp. 466-468
Author(s):  
Cristina Basso ◽  
Peter T Buser ◽  
Stefania Rizzo ◽  
Massimo Lombardi ◽  
Gaetano Thiene
Keyword(s):  
Cardiovascular Magnetic Resonance ◽  
Magnetic Resonance ◽  
Cardiac Function ◽  
Tissue Characterization ◽  
Cardiac Tissue ◽  
Malignant Tumours ◽  
Magnetic Resonance Scanner ◽  
Cardiac Tumours ◽  
Cardiac Masses ◽  
Cmr Imaging

Cardiovascular magnetic resonance (CMR) imaging of cardiac masses provides a multplicity of information, e.g. on localization, extension, dimensions, infiltration of cardiac and/or peri-/para-cardiac tissue, influence on cardiac function and flow, vascularization of the mass, and most importantly tissue characterization. However, since time to investigate a patient within the magnetic resonance scanner is limited, it is recommended to follow published CMR protocols in order to perform highly efficient CMR examinations and nevertheless receive optimized information per unit of investigational time. Furthermore, some criteria may allow differentiation of benign from malignant tumours.

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