Incidence and definition of takotsubo syndrome

ESC CardioMed ◽  
2018 ◽  
pp. 1278-1280
Author(s):  
Abhiram Prasad
Keyword(s):  
Heart Failure ◽  
Acute Coronary Syndrome ◽  
Diagnostic Criteria ◽  
Apical Ballooning ◽  
Stress Cardiomyopathy ◽  
Apical Ballooning Syndrome ◽  
Takotsubo Syndrome ◽  
Coronary Syndrome ◽  
Definition Of ◽  
European Society Of Cardiology

Takotsubo syndrome (TTS) is also commonly known as apical ballooning syndrome and stress cardiomyopathy. The incidence of TTS has consistently been estimated to be close to 2% of all patients presenting with an initial diagnosis of an acute coronary syndrome, and perhaps as high as about 5% of women. TTS is a diagnosis of exclusion and in the absence of a diagnostic test, there is the need for diagnostic criteria. The Mayo Clinic diagnostic criteria are the most widely cited. The Heart Failure Association of the European Society of Cardiology published criteria in 2015. An update to this chapter includes the most recent criteria from 2018.

Incidence and definition of takotsubo syndrome

ESC CardioMed ◽  
2018 ◽  
pp. 1278-1280
Author(s):  
Abhiram Prasad
Keyword(s):  
Heart Failure ◽  
Acute Coronary Syndrome ◽  
Diagnostic Criteria ◽  
Apical Ballooning ◽  
Stress Cardiomyopathy ◽  
Apical Ballooning Syndrome ◽  
Takotsubo Syndrome ◽  
Coronary Syndrome ◽  
Definition Of ◽  
European Society Of Cardiology

Takotsubo syndrome (TTS) is also commonly known as apical ballooning syndrome and stress cardiomyopathy. The incidence of TTS has consistently been estimated to be close to 2% of all patients presenting with an initial diagnosis of an acute coronary syndrome, and perhaps as high as about 5% of women. TTS is a diagnosis of exclusion and in the absence of a diagnostic test, there is the need for diagnostic criteria. The Mayo Clinic diagnostic criteria are the most widely cited. The Heart Failure Association of the European Society of Cardiology published the most recent criteria in 2015.

scholarly journals Tako-Tsubo syndrome. Approach to the subject and Report of 2 cases

2021 ◽  
Vol 4 (4) ◽  
pp. 01-05
Author(s):  
Claribel Pazos
Keyword(s):  
Heart Failure ◽  
Apical Ballooning ◽  
Stress Cardiomyopathy ◽  
Takotsubo Syndrome ◽  
Angiographic Study ◽  
Subsequent Recovery ◽  
Coronary Syndrome ◽  
Electrocardiographic Changes ◽  
The Subject ◽  
Anterior Infarction

Takotsubo syndrome, or stress cardiomyopathy, is a relatively rare transient and reversible cardiomyopathy, although its diagnosis has increased in recent years, it presents as an acute coronary syndrome (ACS) or acute heart failure, its incidence is unknown exactly in Latin America and in Cuba. We present 2 cases seen in our hospital, both 63 and 55-year-old women with typical precordial pressure pain, the first triggering psychological stress and the second physical, with electrocardiographic changes consistent with anterior infarction and cardiogenic shock, which were found in the coronary angiographic study observed normal coronary arteries and ventriculography determined apical ballooning of the left ventricle characteristic of the syndrome, with subsequent recovery and favorable clinical evolution at 6 months.

Abstract P478: Trends in Concurrent Heart Failure and Acute Coronary Syndrome Hospitalizations: A Literature Review

Circulation ◽  
2020 ◽  
Vol 141 (Suppl_1) ◽  
Author(s):  
Sarah Godfrey ◽  
Laura Cohen ◽  
Susan Hennessy ◽  
Brandon Bellows
Keyword(s):  
Heart Failure ◽  
Acute Coronary Syndrome ◽  
Clinical Practice ◽  
Literature Review ◽  
Pooled Analysis ◽  
Coronary Syndrome ◽  
St Elevation ◽  
Recent Trends ◽  
Definition Of ◽  
Over Time

Purpose: Patients who present with concurrent heart failure (HF) and acute coronary syndrome (ACS) have an increased risk of mortality, but changes in clinical practice have improved clinical outcomes. We sought to examine recent trends in concurrent HF and ACS hospitalizations in the United States (US) through review of published literature. Methods: We searched the Medline and PubMed databases for studies published after January 1, 2000 reporting the hospitalizations for HF with concurrent acute coronary syndromes. We included studies performed in the US or with at least 25% US participants, that reported the proportion with concurrent HF and ACS, and used a clinical definition of HF (e.g. Killip Class II or III, NYHA Class, or Framingham Criteria). Studies were reviewed by and data was extracted using a standardized form. We extracted study and patient characteristics, definition of HF, and rates of concurrent HF and ACS hospitalizations. We categorized included studies by ACS type: (1) non-specific myocardial infarction (MI) or ACS, (2) non-ST elevation (NSTE) MI or NSTE-ACS, or (3) ST elevation (STE) MI. We descriptively examined recent trends in hospitalizations for concurrent HF and ACS over time; rates reported for multiple time periods or ACS types were considered separately. Results: We identified 23 observational studies, systematic reviews, and randomized clinical trials. Of these, we excluded 13 due to non-US populations, use of non-clinical definitions of HF (i.e., diagnosis codes), or not reporting rates of concurrent HF and ACS. Of the 10 included studies, 7 reported concurrent HF with non-specific MI or ACS from 1975 through 2005 across multiple registries and literature reviews. Rates ranged from 12.5% to 48.0% with no clear time-related trends. We identified 3 studies reporting concurrent HF with NSTEMI or NSTE-ACS from pooled analysis or the Global Registry of Acute Coronary Events (GRACE) registry from 1994 to 2008. Reported rates ranged from 8.2%-15.7% for studies starting in the 1990s with one study reporting and 6.1% in 2005. We identified 4 studies reporting concurrent HF with STEMI, including a pooled analysis, the GRACE registry, and a clinical trial. Rates of concurrent HF with STEMI appeared to decrease over time from 32.5% in 1990 to 1998, 15.6%-19.5% from 1999 to 2001, and 2.6%-11.0% in 2005. Conclusion: Our literature review found that there may be a decrease in concurrent HF and STEMI hospitalizations in recent decades, but no apparent trends with other types of ACS. This may be related to emphasis on early revascularization strategies, improved primary prevention, and/or earlier time to presentation due to increasing public awareness.. However, there was a dearth of data reporting concurrent HF and ACS hospitalization within the last decade. Further research is needed to understand the impact of multiple changes in clinical practice on secular trends.

scholarly journals Takotsubo syndrome in elderly woman: The diagnosis by transthoracic echocardiography

2019 ◽  
Vol 7 ◽  
pp. 2050313X1987892
Author(s):  
Inggita Hanung Sulistya ◽  
Anggoro Budi Hartopo ◽  
Lucia Kris Dinarti ◽  
Budi Yuli Setianto
Keyword(s):  
Acute Coronary Syndrome ◽  
Left Ventricle ◽  
Transthoracic Echocardiography ◽  
Troponin I ◽  
Acute Chest Pain ◽  
Apical Ballooning ◽  
Transient Condition ◽  
Takotsubo Syndrome ◽  
Coronary Syndrome ◽  
Concentric Hypertrophy

Takotsubo syndrome has increasingly been recognized in the differential diagnosis of patients presenting with acute chest pain. Those affected are typically older women suffering after an emotional or physical stress. Normally it is a transient condition but complications including death have been reported. We reported a case of takotsubo syndrome who was initially diagnosed as acute coronary syndrome. The patient presented with typical angina, ST-T segment changes, and elevated high sensitive–troponin I. Coronary angiography showed normal coronary arteries. Transthoracic echocardiography revealed mild left atrial dilatation and left ventricle concentric hypertrophy, reduced left ventricle ejection fraction with circumferential hypokinetic, apical ballooning, systolic anterior motion, left ventricle outflow tract obstruction, and sigmoid septum hypertrophy. One month later, patient recovered and transthoracic echocardiography revealed improved heart anatomy and function. To differentiate takotsubo syndrome with other conditions, especially acute coronary syndrome, is crucial. Their clinical presentations are similar but the managements are different. The transthoracic echocardiography holds an important role in supporting the diagnosis of takotsubo syndrome.

Abstract P366: Apical Ballooning Syndrome in Women and Outcome

2011 ◽  
Vol 4 (suppl_1) ◽  
Author(s):  
Jagdesh Kandala ◽  
Shanmugam Uthamalingam ◽  
Sarika Ballari ◽  
Marilyn Daley ◽  
Robert Capodilupo
Keyword(s):  
Acute Coronary Syndrome ◽  
Chest Pain ◽  
Ace Inhibitors ◽  
Beta Blockers ◽  
Apical Ballooning ◽  
Fisher Exact Test ◽  
Apical Ballooning Syndrome ◽  
Post Discharge ◽  
Reduced Ejection Fraction ◽  
Coronary Syndrome

Background: Apical ballooning syndrome (ABS) management has not been extensively studied. These patients are often managed as those with acute coronary syndrome. The objective of our study is to examine the role of medications like selective beta-blockers, statins, clopidogrel, and angiotensin converting (ACE) inhibitors post-discharge. Methods: From January, 2002 to December, 2007 18 consecutive patients were treated for ABS. Each patient was assessed by history, physical exam, electrocardiogram, laboratory investigations, telemetry, echocardiogram, coronary angiogram and later, by a follow up echo in 4-8 weeks. Results: All patients were female, the majority were caucasian and postmenopausal. The most common presentation was angina. Common EKG findings were T wave inversions, and prolonged QTc. Echocardiogram images demonstrated mid-ventricular and apical wall motion abnormalities and reduced ejection fraction, this was later confirmed by angiogram. All patients were alive at the time of discharge. Medications these patients received post discharge were selective beta-blockers 87.5 % (14/16), aspirin 100% (16/16), statins 62.5% (10/16), ACE inhibitors 81.2% ( 13/16), and clopidogrel 12.5% (2/16). After discharge from the hospital 31.2% (5/16) had recurrent chest pain on the above medical management. Recurrent chest pain developed in three out of five patients discharged on selective beta-blockers (p < 0.08, Fisher exact) and in three out of five patients who were discharged on statins (p < 0.65, Fisher exact). Patients who developed recurrent chest pain discharged on ACE inhibitors were four out of five (p<0.70, fisher exact test), and on clopidogrel were 0 out of five (p <0.45, fisher exact). Conclusion: Patients from our study have a higher rate of recurrent chest pain than previously reported. Chronic treatment with selective beta-blockers, ACE inhibitors, clopidogrel, and statins did not reduce the frequency of recurrent chest pain post-discharge. Although there is no evidence demonstrating a benefit, these patients are often treated as per guidelines for acute coronary syndrome. Our study demonstrates that ABS patients are subjected to ineffective treatment and there is an emergent need for management guidelines

scholarly journals CARDIOONCOLOGY: CHEMOTHERAPY DRUGS AND RADIATION THERAPY IMPACT ON CARDIOVASCULAR SYSTEM

2016 ◽  
Vol 7 (4) ◽  
pp. 41-48
Author(s):  
D P Doundoua ◽  
A V Staferov ◽  
A V Sorokin ◽  
A G Kedrova
Keyword(s):  
Heart Failure ◽  
Acute Coronary Syndrome ◽  
Radiation Therapy ◽  
Cardiovascular System ◽  
Limb Ischemia ◽  
Anticancer Therapy ◽  
Vascular Toxicity ◽  
Chemotherapy Drugs ◽  
Coronary Syndrome ◽  
Definition Of

Anticancer therapy can cause angina pectoris, acute coronary syndrome, stroke, critical limb ischemia, arterial hypertension, arrhythmias and heart failure. The new specialization in cardiology, called cardiooncology, exploring the complications of cardiovascular system, arising during the treatment of cancer. The first part of the review, based on the publications of the last decades, is dedicated to the definition of cardiooncology, mechanisms of cardiac and vascular toxicity with a number of anticancer drugs affecting the cardiovascular system.

scholarly journals Acute Heart Failure in Apical Ballooning Syndrome (TakoTsubo/Stress Cardiomyopathy)

2011 ◽  
Vol 57 (12) ◽  
pp. 1400-1401 ◽  
Author(s):  
Malini Madhavan ◽  
Charanjit S. Rihal ◽  
Amir Lerman ◽  
Abhiram Prasad
Keyword(s):  
Heart Failure ◽  
Acute Heart Failure ◽  
Apical Ballooning ◽  
Stress Cardiomyopathy ◽  
Apical Ballooning Syndrome

Acute coronary syndrome or apical ballooning syndrome?

2012 ◽  
Vol 28 (1) ◽  
pp. 130-133 ◽  
Author(s):  
Yuichiro Maekawa ◽  
Akio Kawamura ◽  
Shinsuke Yuasa ◽  
Yohei Ohno ◽  
Takahide Arai ◽  
...  
Keyword(s):  
Acute Coronary Syndrome ◽  
Apical Ballooning ◽  
Apical Ballooning Syndrome ◽  
Coronary Syndrome
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