Schizophrenia, bipolar disorder, obsessive–compulsive disorder, and personality disorder

2010 ◽  
pp. 5324-5328
Author(s):  
Stephen Lawrie

Schizophrenia—is characterized by phenomena that qualitatively differ from everyday experience. These may be ‘positive symptoms’, commonly auditory hallucinations and/or bizarre delusions, or ‘negative symptoms’, commonly including a loss of emotion (flat affect), apathy, self-neglect, and social withdrawal. Acute positive symptoms generally respond well to any antipsychotic drug, but prognosis is often poor, with most suffering chronic symptoms, numerous relapses, unemployment, and social isolation....

Author(s):  
Edmund T. Rolls

The book will be valuable for those in the fields of neuroscience, neurology, psychology, psychiatry, biology, animal behaviour, economics, and philosophy, from the undergraduate level upwards. The book is unique in providing a coherent multidisciplinary approach to understanding the functions of one of the most interesting regions of the human brain, in both health and in disease, including depression, bipolar disorder, autism, and obsessive-compulsive disorder. There is no competing book published in the last 10 years.


2010 ◽  
Vol 22 (2) ◽  
pp. 81-86 ◽  
Author(s):  
Cilly Klüger Issler ◽  
Emel Serap Monkul ◽  
José Antonio de Mello Siqueira Amaral ◽  
Renata Sayuri Tamada ◽  
Roseli Gedanke Shavitt ◽  
...  

Issler CK, Monkul ES, Amaral JAMS, Tamada RS, Shavitt RG, Miguel EC, Lafer B. Bipolar disorder and comorbid obsessive-compulsive disorder is associated with higher rates of anxiety and impulse control disorders.Objective:Although bipolar disorder (BD) with comorbid obsessive-compulsive disorder (OCD) is highly prevalent, few controlled studies have assessed this comorbidity. The objective of this study was to investigate the clinical characteristics and expression of comorbid disorders in female BD patients with OCD.Method:We assessed clinically stable female outpatients with BD: 15 with comorbid OCD (BD+OCD group) and 15 without (BD/no-OCD group). All were submitted to the Structured Clinical Interview for DSM-IV, with additional modules for the diagnosis of kleptomania, trichotillomania, pathological gambling, onychophagia and skin picking.Results:The BD+OCD patients presented more chronic episodes, residual symptoms and previous depressive episodes than the BD/no-OCD patients. Of the BD+OCD patients, 86% had a history of treatment-emergent mania, compared with only 40% of the BD/no-OCD patients. The following were more prevalent in the BD+OCD patients than the BD/no-OCD patients: any anxiety disorder other than OCD; impulse control disorders; eating disorders; and tic disorders.Conclusion:Female BD patients with OCD may represent a more severe form of disorder than those without OCD, having more depressive episodes and residual symptoms, and being at a higher risk for treatment-emergent mania, as well as presenting a greater anxiety and impulse control disorder burden.


2006 ◽  
Vol 94 (1-3) ◽  
pp. 151-156 ◽  
Author(s):  
A PASHINIAN ◽  
S FARAGIAN ◽  
A LEVI ◽  
M YEGHIYAN ◽  
K GASPARYAN ◽  
...  

2015 ◽  
Vol 230 (3) ◽  
pp. 800-805 ◽  
Author(s):  
Filiz Ozdemiroglu ◽  
Levent Sevincok ◽  
Gulnur Sen ◽  
Sanem Mersin ◽  
Oktay Kocabas ◽  
...  

2020 ◽  
Author(s):  
POONAM BHARTI ◽  
Angad harshbir singh ◽  
Parul Gupta

Abstract Background- Obsessive-compulsive disorder (OCD) is one of the most frequently associated comorbidities in bipolar disorder (BD). While this presents a challenge in understanding the phenomenology and also the treatment aspect of co occurrence of mania with OCD. Case history- The index case is of an elderly female who presented with OC symptoms and while on treatment had mania episodes. The mania episodes presented challenges while managing underlying OC symptoms. Conclusion- The common neurobiological mechanism for the co-morbid illness and treatment lacunae are discussed. The serotonin, dopamine, and glutamate having important role in BD-OCD were evaluated to understand the neurobiological basis of BD-OCD. The index case presented with the challenge of understanding the phenomenology of the illness but also presented with opportunity to learn and successfully manage patients with such co-morbidity. Divalproex and risperidone combo was found to be effective in controlling mania in OCD patients.


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