UTILITY AND SIGNIFICANCE OF ANUPANA

Ayurveda science of life with the aim “Swastasya Swasthya Rakshanam and Aturasya Vikara Prashamanam” has a different approach towards Arogya Sthapana. Anupana concept is one such inseparable concept of Ayurveda in the treatment aspect. Along with the main medicated drug the adjuvant with which it is taken, plays an important role in the success of treatment. Anupana (Vehicle) is a substance that is taken, along with or after the intake of Aahara (food) and Aushada (drug). In the context of food, Anupana helps in better digestion, absorption & provides complete nourishment of the body. It brings some changes in the substance along with which it is administered. It also plays a very significant role in treating the diseases & helps the drug to improve efficacy. On review of literature, Anupana has a multidimensional effect; it will act as a nutritive, stimulant, preventive and curative. Keywords: Anupana, Ahara, Ayurveda, adjuvant

A Review on “Anupana” is the base of Ayurvedic treatment

Ayurveda is the science of life with aim swastasya swasta rakshanam and aturasya vikara prashamanam has a different approach towards arogya sthapana. Anupana is the inseparable concept of Ayurveda in the treatment aspect. It plays a very important role, it brings certain changes in a substance along with which it is administered. Anupana is the one that is taken along with or after medicine. In the context of food, Anupana help in its better digestion and absorption and provides complete nourishment of the body. To cure the diseases the use of proper Anupana along with specific drug therapy is equally important. It acts as a vehicle that carries the drug to its target site, hence this article deals with the importance of Anupana in the Ayurvedic practice.

A novel Ayurvedic medical fumigant powder Bhootastgandha and its effect in Combating Airborne pathogens - A detailed pharmacological activity review

Infectious diseases are becoming popular with every passing day and viral infections among them are the cause for a large number of fatalities since last two decades. All the factors including the lifestyle pave the way to reduced immunity making the human population susceptible to infections. Management of diseases is not only important; prevention of further diseases should also be of prime concern. Infectious diseases that spread through a variety of mediums like air, water etc. requires preventive measures that controls the spread of the microorganisms and keep the preventive aspect intact. Ayurveda treatment has succeeded in achieving both treatment aspect as well as preventative aspect of diseases. Dhoopana Karma is an important modality & primitive method of sterilization which can be used in preventive and curative aspect. The yoga “Bhootastagandha” is taken from the Ayurvedic compilation Sarvaroga Chikitsa Ratnam”. Learning about the practical application of the formulation, the formulation is mentioned among a group of formulations used as fumigating agents. The formulation consists of a group of 8 drugs and all the drugs on pharmacological screening is found to possess Antimicrobial, Antibacterial, Antiviral, Antifungal properties among other pharmacological actions. The details about the pharmacological activity of the drugs are collected from various research articles published. This review article mainly focuses on the phytochemical properties of the ingredient drugs as per Ayurveda classics and the utility of the formulation as an effective fumigant keeping in mind the Antimicrobial, Anti-viral, Anti –Fungal and Anti- Bacterial action of the plants.

Understanding Parkinson’s Disease (PD) in Ayurvedic Prospective

Parkinson’s disease (PD) known as Kampavata in Ayurveda, is a degenerative neurological disorder of central nervous system, mainly affecting the motor system. It is the major cause of disability in the aging society, which usually affects after the age of 50 years. This disease is increasing in its frequency with the world population showing an incidence of 1-2 per 1000 population and has equal sex distribution. Symptoms like Kampa (Tremor), Stambha (Rigidity), Chestasanga (Bradykinesia and Akinesia), Vakvikriti (disturbance in speech) etc were described in different contexts of Charaka Samhita, Susruta Samhita and Basavarajeeyam. There is no cure for Parkinson’s disease, but medications, surgery and multidisciplinary management can provide relief and improve the quality of life of the individual. In the treatment aspect, the drug L-Dopa has shown better results similarly Ayurvedic drugs having the similar compounds are useful in this disorder. Based on the symptoms manifested, the disease can be correlated to Kampavata mentioned in Ayurveda classics. Despite of so many advances in the field of medicine, treatment of PD remains highly symptomatic. This instills the need for Ayurvedic management of Kampavata. The present article is intended to focus on the Nidana, Lakshanas, Samprapthi and the management principles of Parkinson’s disease (Kampavata).

AGATHIYAR KUZHAMBU (HERBO-MINERAL SIDDHA FORMULATION)

Introduction: Agathiyar kuzhambu (A.k) is a herbo-mineral siddha formulation. It is explained in the Siddha Vaith- iya Thiraddu Book. In Siddha Medicine, there are 32 internal & external medicines are explained in the Siddha Literatures. Agathiyar kuzhambu is a one form of the internal medicine which is commonly used in purgation ther- apy. It contains 11 ingredients. Agathiyar kuzhambu has different herbo- mineral ingredients which are having wide range of therapeutic uses. It is commonly used in Siddha OPDs. Aim: The researcher is going to develop the documentary evidence for the effectiveness of Agathiyar kuzhambu. Results and Discussion: Six ingredients herbs have hot potency and Pungent efficacy. These have many pharmacological actions. Commonly, these ingredients are possessed antioxidant, anti-microbial, hepatoprotective, anti-inflammatory, anti-fungal, anthelmintic, anti-dia- betic and anti -hypertensive activity. In Siddha, these ingredients and 5 minerals and metals ingredients were used in many disease conditions. Lots of adjuvants of Agathiyar kuzhambu have hot potency and pungent efficacy. Some of adjuvants have cool potency and sweet efficacy. In Siddha, these adjuvants were used in many disease conditions. Conclusion: According to the above study, Agathiyar kuzhambu may be act as stimulant and osmotic purgative at the same time it can use as a treatment aspect of many diseases. This study gives documentary evidence of Agathiyar kuzhambu as a purgative & possess many pharmacological activities in Siddha medicine. Keywords: Agathiyar kuzhambu, Siddha Medicine, Purgative, Croton tiglium

A COMPARATIVE CLINICAL STUDY OF ‘CHEDANA KARMA & KSHARSUTRA (SETON) KARMA’ (GUGGULU BASED) IN THE MANAGEMENT OF SHALYAJ NADI VRANA(SINUS) W.S.R. TO PILONIDAL SINUS (ASSOCIATED WITH ROPAN LEPA)

A Pilonidal Sinus is a common disease of the natal cleft. Pilonidal Sinus is a track which contains hairs. The incidence of the disease is calculated to be 26 per 100,000 people. Pilonidal disease has a male pre-dominance with a ratio of 3:1. There are several methods to treat pilonidal sinus, but the recurrence rate is more in modern surgical interventions. According to Ayurveda it can be correlated to Salyajanya Nadi Vrana (pilonidal sinus), a type of Nadi Vrana (sinus). Whose etiopathology is described in Nidanasthana and treatment aspect in Chikitsasthana of Susrutha Samhita. Susrutha mentioned the ap-plication of Kshara (caustic alkali) and Ksharsutra (Seton) (Seton) in the management of Nadi Vrana (si-nus). Studies show that by Ayurvedic treatment, it helps to reduce recurrence rate, even though Nadi Vrana (sinus) is said to be Kricchrasadhya (difficult to cure). Hence successful management of this disease de-pends on the knowledge of pathogenesis, patient’s presentation and knowledge on treatment aspects. In this Clinical study, effect of Chedana karma & Ksharsutra (Seton) karma’ (Guggulu based) in the management of Salyajanya Nadi Vrana (pilonidal sinus) w.s.r. To pilonidal sinus (associated with ropan lepa) is seen and conclusion in drawn.

A Review Article on Toxicity Induced Hepatocellular Carcinoma: Through Gara Visa perspective

Hepatocellular carcinoma is the most common primary malignancy of liver in adults and is the common cause of death in people with cirrhosis [1] . The majority of this disease occurs over pre-existing chronic liver cirrhosis but the increased changes in living conditions, food habits and sedentary life style has emerged the disease into a silent killer category independent of cirrhosis. The present modifications in food habits, drug induced toxicity and other environmental toxicity has led to a dramatic rise in HCC even in non-alcoholics. The symptoms and pathogenesis in HCC can be eventually be correlated with Garavisa Lakshana, Samprapthi and the judicious application of its treatment in Ayurveda can concrete a new path in its treatment aspect.

Treatment of complex laryngotracheal stenosis in childhood–experience of a tertiary University Hospital from 2016 to 2019

Background Laryngotracheal stenosis is a major cause of airway obstruction in pediatric age. The correction of such abnormality still remains a challenge, both because of anatomical issues in childhood and also due to the difficulty in having properly trained professionals and adequate hospital facilities. As treatment, many different surgical techniques are offered ranging from endoscopic and less invasive procedures to open surgeries, such as laryngotracheal reconstruction and cricotracheal resection. The treatment for complex laryngotracheal stenosis is considered successful when we have decannulation or resolution of respiratory failure with release from intensive care unit. Eighteen patients who were monitored at the pediatric otorhinolaryngology service between 2016 and 2019 were diagnosed with complex stenosis, with the collection of demographic data, comorbidities, degree of initial stenosis, post-treatment aspect, and whether or not decannulation occurred. Results Of the eighteen cases, three had congenital stenosis, fourteen had acquired stenosis, and one had mixed stenosis. Ages ranged from 4 months old to 15 years old. Six (33.3%) underwent endoscopic dilation procedures only, six (33.3%) underwent laryngotracheoplasty, and five (27.7%) cricotracheal resections. One patient underwent a slide tracheoplasty. Seven patients (38.8%) had to undergo more than one type of procedure to improve stenosis. Out of the eighteen patients, three of them were never tracheostomized. Of the remaining fifteen patients, fourteen (93.3%) were decannulated. Conclusions The success rate in decannulation or the resolution of respiratory failure with discharge from the ICU, after the procedures for correcting stenosis in childhood in our service, was 94.4%.

Cysts of the “Oro-Maxillofacial Region”

Cysts of the Oro-Maxillofacial region have common occurrence in comparison to any other parts of the body. These can be true cysts or pseudocysts and can be found in the jaw bones or in the soft tissues. Cysts are of various types, and over the years, various classifications are put forward, which are helpful to identify each cyst, based on its origin and its clinical and histopathological presentation. Based on the classification, one can also decide the treatment plan accordingly. The classifications are given by various researchers and also by WHO. In this chapter, various odontogenic and nonodontogenic cysts and their treatment aspect are discussed in detail.