Differential Diagnosis of Autism Spectrum Disorder Across the Lifespan

2016 ◽  
pp. 47-66
Author(s):  
Isobel W. Green ◽  
Christen L. Kidd ◽  
Robert E. Accordino
2019 ◽  
Vol 58 (11-12) ◽  
pp. 1232-1238
Author(s):  
Annette E. Richard ◽  
Elise K. Hodges ◽  
Martha D. Carlson

Early diagnosis of autism spectrum disorder (ASD) has focused on differentiating children with ASD from neurotypical children. However, many children presenting with concern for ASD are ultimately diagnosed with language disorder (LD). This study aimed to identify differences in parent-rated development and behavior among children ages 2 to 5 years presenting with concern for ASD who were diagnosed with either ASD or LD. Children with ASD were rated as more socially withdrawn and more delayed in social development and self-help skills than those with LD. Parent-rated developmental delays were positively correlated with scores on an autism screening measure and with social withdrawal and pervasive developmental problems among children with ASD. Among those with LD, parent-rated social and self-help development were positively correlated with social withdrawal and attention problems. Thus, parent ratings of social withdrawal and development of social and self-help skills may facilitate differential diagnosis of ASD and LD in children ages 2 to 5 years.


2016 ◽  
Vol 33 (S1) ◽  
pp. S356-S356
Author(s):  
I. Peixoto ◽  
R. Velasco Rodrigues ◽  
C. Marques

IntroductionDespite categorical differentiation, autistic and psychotic disorders are historically related diagnostic entities and there is still much controversy regarding their limits and developmental course. Particularly in children, the presence of idiosyncratic fears, difficulties in the social sphere and thought disorder are important factors in the differential diagnosis. There are some research-derived clinical constructs that operationalize symptomatology aiming to highlight the interfaces and the overlap between such disorders. Their clinical implications can be extremely relevant in the face of the limits of current nosology.ObjetivesTo phenomenologically describe differentiating parameters and high-risk clinical profiles for the development of psychosis in children with autism spectrum disorder.MethodsSelective review of the literature in PubMed (MEDLINE). Illustration with a clinical case vignette.ResultsThe clinical case reflects well the difficulties posed in the differential diagnosis due to the multiple interfaces between autism and psychosis. Constructs such as “multiple complex developmental disorder” or “multidimensionally impaired syndrome” allow a clearer and more practice-friendly characterization of such individuals.ConclusionThe constelation of symptoms identified in these criteria may become useful through the definition of subgroups of autism spectrum disorder individuals with complex psychopathology. Studies in this regard are still scarce, but the validation and reproduction of the positive results observed in the near future can help optimize the clinical approaches in these children.Disclosure of interestThe authors have not supplied their declaration of competing interest.


Author(s):  
Ojea Rúa Manuel

This study's basic aim is evaluating the Semantic Integration Scale (SIS) to give a specific complementary differential instrument in relation to information processing shape of people with autism spectrum disorder (ASD) and, therefore, facilitate the differential diagnosis of people with ASD regarding normotypic people. A total of 376 participants have been selected between 10 and 16 age, distributed in 2 groups, 1 experimental groups formed of people with ASD= 156 and 1 normotypical control group, composed by 220 participants. The conclusive differential analysis of the comparative level between experimental and control group, corresponding to 6 subdimensions of SIS, carried out through t-test for 2 independent samples, it´s concluded the comparative data are significantly different between both groups: experimental and control group, which allows deducing the specificity of this Scale like complementary diagnosis adapted to people with ASD.


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