Hamartoma and Benign Tumor-like Lesions

Chest Imaging ◽  
2019 ◽  
pp. 301-306
Author(s):  
Tyler H. Ternes
Keyword(s):  
Surgical Resection ◽  
Lung Neoplasms ◽  
Rapid Growth ◽  
Benign Neoplasms ◽  
Extraadrenal Paraganglioma ◽  
Pulmonary Chondroma ◽  
Pulmonary Hamartoma ◽  
Tumor Like Lesions ◽  
Lungs And Airways ◽  
Central Lesions

Pulmonary hamartomas are benign neoplasms comprised of various mesenchymal components. The presence of chondroid calcification (popcorn appearance) and/or macroscopic fat can be diagnostic of hamartoma. Very slow growth is an expected finding. Treatment of pulmonary hamartoma is usually conservative. Surgical resection can be considered if the CT findings are nondiagnostic, if biopsy is inconclusive, or if the lesion demonstrates rapid growth. Surgery should also be considered in patients with central lesions and postobstructive atelectasis or infection. Hamartomas account for the majority of benign lung neoplasms. Other benign neoplasms occurring in the lungs and airways include lipoma, chondroma, and leiomyoma and are very rare. If a pulmonary chondroma is diagnosed, additional investigation should be considered to exclude concurrent leiomyosarcoma and extraadrenal paraganglioma (Carney Triad).

Gastric leiomyoblastoma associated with extraadrenal paraganglioma and pulmonary chondroma: A new case of Carney's triad

1993 ◽  
Vol 28 (12) ◽  
pp. 1545-1549 ◽  
Author(s):  
M.D. Argos ◽  
A. Ruiz ◽  
F. Sanchez ◽  
C. Garcia ◽  
J. Gaztambide
Keyword(s):  
Extraadrenal Paraganglioma ◽  
Carney’S Triad ◽  
Pulmonary Chondroma

Rapid growth of cutaneous metastases after surgical resection of thrombospondin-secreting small blue round cell tumor of childhood

1998 ◽  
Vol 29 (10) ◽  
pp. 1039-1044 ◽  
Author(s):  
Susan E. Crawford ◽  
E. Martin Flores-Stadler ◽  
Lijun Huang ◽  
Xiao-Di Tan ◽  
Mark Ranalli ◽  
...  
Keyword(s):  
Surgical Resection ◽  
Rapid Growth ◽  
Cell Tumor ◽  
Round Cell ◽  
Cutaneous Metastases ◽  
Round Cell Tumor

Pulmonary Chondroma: A Tumor Associated With Carney Triad and Different From Pulmonary Hamartoma

2007 ◽  
Vol 31 (12) ◽  
pp. 1844-1853 ◽  
Author(s):  
Fausto J. Rodriguez ◽  
Marie-Christine Aubry ◽  
Henry D. Tazelaar ◽  
Jeff Slezak ◽  
J. Aidan Carney
Keyword(s):  
Carney Triad ◽  
Pulmonary Chondroma ◽  
Pulmonary Hamartoma

Benign Neoplasms and Tumor-Like Lesions

2005 ◽  
pp. 107-158 ◽  
Author(s):  
Roberto Maroldi ◽  
Marco Berlucchi ◽  
Davide Farina ◽  
Davide Tomenzoli ◽  
Andrea Borghesi ◽  
...  
Keyword(s):  
Benign Neoplasms ◽  
Tumor Like Lesions

A Review of Intractable Facial Pain Secondary To Underlying Lung Neoplasms

Cephalalgia ◽  
2003 ◽  
Vol 23 (1) ◽  
pp. 2-5 ◽  
Author(s):  
EJ Eross ◽  
DW Dodick ◽  
JW Swanson ◽  
DJ Capobianco
Keyword(s):  
Computed Tomography ◽  
Radiation Therapy ◽  
Surgical Resection ◽  
Lung Neoplasms ◽  
Facial Pain ◽  
Lung Neoplasm ◽  
Lung Mass ◽  
Refractory Pain ◽  
Clinical Triad

We describe a 63-year-old smoker who suffered from intractable facial pain secondary to an underlying lung neoplasm. Data from 30 previously reported and similar cases are also summarized. The clinical triad of a smoker suffering from periauricular pain and an elevated ESR should alert the clinician to the possibility of an occult lung mass. In these cases a computed tomography of the chest should always be obtained. Previously refractory pain typically responds to surgical resection of the mass and/or radiation therapy.

scholarly journals Pulmonary Hamartoma Associated With Lung Cancer (PHALC Study): Results of a Multicenter Study

Lung ◽  
2021 ◽  
Author(s):  
Alfonso Fiorelli ◽  
Antonio D’Andrilli ◽  
Annalisa Carlucci ◽  
Giovanni Vicidomini ◽  
Giacomo Argento ◽  
...  
Keyword(s):  
Risk Factors ◽  
Lung Cancer ◽  
Surgical Resection ◽  
Endoscopic Resection ◽  
Multicenter Study ◽  
Benign Tumor ◽  
Malignant Degeneration ◽  
Study Results ◽  
Historical Series ◽  
Pulmonary Hamartoma

Abstract Purpose Pulmonary hamartoma is the most common benign tumor of the lung. We analyzed a 20-year historical series of patients with pulmonary hamartoma undergoing surgical resection, aiming to evaluate the characteristics, the outcomes, and the association between hamartoma and lung cancer. Methods It was a retrospective multicenter study including the data of all consecutive patients with pulmonary hamartoma undergoing surgical resection. The end-points were to evaluate: (i) the characteristics of hamartoma, (ii) outcomes, and (iii) whether hamartoma was a predictive factor for lung cancer development Results Our study population included 540 patients. Upfront surgical or endoscopic resection was performed in 385 (71%) cases while in the remaining 155 (29%) cases, the lesions were resected 20 ± 3.5 months later due to increase in size. In most cases, lung sparing resection was carried out including enucleation (n = 259; 48%) and wedge resection (n = 230; 43%) while 5 (1%) patients underwent endoscopic resection. Only two patients (0, 2%) had major complications. One patient (0.23%) had recurrence after endoscopic resection, while no cases of malignant degeneration were seen (mean follow-up:103.3 ± 93 months). Seventy-six patients (14%) had associated lung cancer, synchronous in 9 (12%) and metachronous in 67 (88%). Only age > 70-year-old (p = 0.0059) and smokers > 20 cigarettes/day (p < 0.0001) were the significant risk factors for lung cancer. Conclusion PH was a benign tumor, with no evidence of recurrence and/or of malignant degeneration after resection. The association between hamartoma and lung cancer was a spurious phenomenon due to common risk factors.

scholarly journals Asymptomatic Glomus Tumor of the Mediastinum

2015 ◽  
Vol 2015 ◽  
pp. 1-3 ◽  
Author(s):  
Meletios Kanakis ◽  
Nikoletta Rapti ◽  
Maria Chorti ◽  
Achilleas Lioulias
Keyword(s):  
Surgical Resection ◽  
Glomus Tumor ◽  
Clinical Symptoms ◽  
Benign Neoplasms ◽  
Glomus Tumors ◽  
Glomus Cells ◽  
Anatomic Distribution

Glomus tumors are rare benign neoplasms that predominate in limbs. Infrequently, they can occur in a wide anatomic distribution, to include sites not known to contain glomus cells. Although glomus tumors are usually small, pain and tenderness are common clinical symptoms. We report the case of a 69-year-old man with an asymptomatic large mediastinal glomus tumor, who underwent surgical resection.

Airways Disease

Chest Imaging ◽  
2019 ◽  
pp. 309-311
Author(s):  
Brent P. Little
Keyword(s):  
Smooth Muscle ◽  
Epithelial Cells ◽  
Pulmonary Nodule ◽  
Benign Neoplasm ◽  
Lung Tumors ◽  
Benign Neoplasms ◽  
Recurrent Pneumonia ◽  
Cartilage Calcification ◽  
Small Pulmonary Nodule ◽  
Pulmonary Hamartoma

Pulmonary hamartoma is a benign neoplasm of the lung. It accounts for the majority of benign lung tumors. A hamartoma is composed of a variety of mesenchymal elements that may include cartilage, calcification, fat, epithelial cells, and smooth muscle. While benign, they are considered true neoplasms, and may demonstrate slow growth. Hamartomas are most commonly discovered in the 6th decade of life. Men have a 2-to-3 fold increased incidence compared to women. Most hamartomas are discovered incidentally. However, patients may rarely present with symptoms such as cough, hemoptysis, or recurrent pneumonia due to lesion proximity to the airway. On CT, hamartoma classically manifests as a small pulmonary nodule with intrinsic chondroid calcification and fat. These findings are essentially diagnostic of hamartoma. However, only 60% of hamartomas contain macroscopic fat, and even fewer (15%) exhibit characteristic “popcorn” calcification. Most hamartomas do not require resection, unless they are symptomatic. Other benign lesions also occur in the lung, but are much less common. A chondroma differs from a hamartoma in that is entirely comprised of cartilage. Chondromas are a component of Carney triad, which is also comprised of gastric leiomyosarcomas and extraadrenal paragangliomas. Lipomas and leiomyomas are other rare benign neoplasms, composed of fat and smooth muscle, respectively. Benign neurogenic neoplasms may also occur within the central airways.

scholarly journals Solitary Fibrous Tumor of the Pleura: Case Report and Literature Review

2020 ◽  
Vol 17 (6) ◽  
pp. 65-76
Author(s):  
Marilena Stoian ◽  
Lucia Indrei ◽  
Roxana Stănică ◽  
Victor Stoica
Keyword(s):  
Surgical Resection ◽  
Benign Neoplasms ◽  
Limited Data ◽  
Treatment Needs ◽  
Solitary Fibrous Tumours ◽  
Pathologic Features ◽  
Complete Surgical Resection ◽  
Fibrous Tumor

Abstract Solitary fibrous tumours of the pleura (SFTPs) are rare neoplasms, usually described as relatively benign neoplasms and only 10-20% presenting malignant features. Imagistic investigations are useful in the incipient evaluation of SFTPs, and the histopathological and immunohistochemical examinations after surgical resection are mandatory for establishing the diagnosis and for differentiating SFTPs from other aetiologies of pleural masses. The unpredictable evolution (10%-20% of the cases reported in literature display malignant features) and limited data regarding the treatment needs an early detection, a complete surgical resection and long-term imagistic follow-up. We present a case of SFTPs alongside a review of the typical clinical, imagistic and pathologic features consistent with this diagnosis.

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