A NHS Foundation Trust v MC [2020] EWCOP 33: Revisiting Best Interests and ‘Altruistic’ Incapacitous Stem Cell Donation

2021 ◽  
Author(s):  
Bonnie Venter
Keyword(s):  
Stem Cell ◽  
Peripheral Blood Stem Cell ◽  
Case Note ◽  
Best Interests ◽  
Best Interest ◽  
Decision Making Capacity ◽  
Key Players ◽  
Judicial Reasoning ◽  
Stem Cell Donation ◽  
Practical Implications

Abstract In A NHS Foundation Trust v MC, the Court of Protection revisits the question of whether adults should be allowed to act as bone marrow or peripheral blood stem cell donors if they lack decision-making capacity. This case note explores the positive and problematic implications of the case based on points that were raised in the judicial reasoning that specifically relate to i) practical implications concerning the key players in this environment, ii) the risk analysis within the best interest determination, iii) altruism and iv) the wider context as it relates to minor donors who lack capacity.

scholarly journals Retrospective Analysis of 37,287 Observation Years after Peripheral Blood Stem Cell Donation

2017 ◽  
Vol 23 (6) ◽  
pp. 1011-1020 ◽  
Author(s):  
Alexander H. Schmidt ◽  
Thilo Mengling ◽  
Camila J. Hernández-Frederick ◽  
Gabi Rall ◽  
Julia Pingel ◽  
...  
Keyword(s):  
Stem Cell ◽  
Retrospective Analysis ◽  
Peripheral Blood ◽  
Peripheral Blood Stem Cell ◽  
Blood Stem Cell ◽  
Stem Cell Donation

scholarly journals Reducing Central Venous Catheter Use in Peripheral Blood Stem Cell Donation: Quality Improvement Report

2017 ◽  
Vol 6 (1) ◽  
pp. u211975.w4817
Author(s):  
Samer Ghazi ◽  
Ahmed Alaskar ◽  
Mohsen Alzahrani ◽  
Moussab Damlaj ◽  
Khadega A Abuelgasim ◽  
...  
Keyword(s):  
Stem Cell ◽  
Quality Improvement ◽  
Central Venous Catheter ◽  
Peripheral Blood ◽  
Peripheral Blood Stem Cell ◽  
Venous Catheter ◽  
Blood Stem Cell ◽  
Central Venous ◽  
Stem Cell Donation

Legislators’ perceptions of unaccompanied children seeking asylum

2015 ◽  
Vol 11 (4) ◽  
pp. 239-252 ◽  
Author(s):  
Daniel Hedlund ◽  
Ann-Christin Cederborg
Keyword(s):  
Social Research ◽  
Migration Policy ◽  
Best Interests ◽  
Unaccompanied Minors ◽  
Life Situation ◽  
Best Interest ◽  
Policy And Practice ◽  
Content Type ◽  
Unaccompanied Children ◽  
Practical Implications

Purpose – The purpose of this paper is to explore how individual legislators perceive unaccompanied minors seeking asylum, their life situation, needs and best interests. Design/methodology/approach – The total number of participants were 15. Thematic analysis (Braun and Clarke, 2006) was used in order to identify and analyze patterns in the interview data. The authors focused on their responses to the questions about the best interest of the child in migration policy and practice, and how this principle was related to unaccompanied children seeking asylum. Findings – The main finding is that chronological age becomes a key sign for how legislators understand the life situation, needs and best interests of unaccompanied children. Also, the findings from this study suggest that the moralizing welfare ideology of the past is still present in political discourse and social planning, construing unaccompanied minors as an ambivalent category between civilization and savagery. The findings from this study indicate that legislators enact reforms of importance for unaccompanied children without considering them as agents of their own future, with their own motives and reasons to seek asylum. Practical implications – The findings from this study indicate a need to adapt the understanding of the existing Aliens Act (SFS 2005:716) to the knowledge that unaccompanied minors need to be assessed on their own terms. Originality/value – This study contributes to increasing the understanding about how the subjective values of legislators may have influenced migration reform in Sweden that can be valuable to both legal and social research, as well as policy planners.

Clinical outcomes after peripheral blood stem cell donation by related donors: a Dutch single-center cohort study

Transfusion ◽  
2012 ◽  
Vol 53 (1) ◽  
pp. 96-103 ◽  
Author(s):  
Johanna C. Wiersum-Osselton ◽  
Suzanna M. van Walraven ◽  
Ivan Bank ◽  
A. Mariëtte Lenselink ◽  
Willem E. Fibbe ◽  
...  
Keyword(s):  
Cohort Study ◽  
Stem Cell ◽  
Clinical Outcomes ◽  
Peripheral Blood ◽  
Peripheral Blood Stem Cell ◽  
Blood Stem Cell ◽  
Single Center ◽  
Stem Cell Donation

scholarly journals Effect of the preventative allopurinol therapy within the framework of the peripheral blood stem cell donation

2018 ◽  
Vol 3 (2) ◽  
pp. 117-125 ◽  
Author(s):  
Elena Müller ◽  
Miriam Hübner ◽  
Silja Kuderer ◽  
Marie Prechtl ◽  
Jutta Rox ◽  
...  
Keyword(s):  
Stem Cell ◽  
Peripheral Blood ◽  
Peripheral Blood Stem Cell ◽  
Blood Stem Cell ◽  
Stem Cell Donation

High-activity samarium-153-EDTMP therapy followed by autologous peripheral blood stem cell support in unresectable osteosarcoma

2001 ◽  
Vol 40 (06) ◽  
pp. 215-220 ◽  
Author(s):  
S. Bielack ◽  
S. Flege ◽  
J. Eckardt ◽  
J. Sciuk ◽  
H. Jürgens ◽  
...  
Keyword(s):  
Stem Cells ◽  
Stem Cell ◽  
High Activity ◽  
Peripheral Blood ◽  
Peripheral Blood Stem Cell ◽  
Blood Stem Cell ◽  
High Dose ◽  
External Radiotherapy ◽  
Primary Tumor Site ◽  
Hematopoietic Stem

Summary Purpose: Despite highly efficacious chemotherapy, patients with osteosarcomas still have a poor prognosis if adequate surgical control cannot be obtained. These patients may benefit from therapy with radiolabeled phosphonates. Patients and Methods: Six patients (three male, three female; seven to 41 years) with unresectable primary osteosarcoma (n = 3) or unresectable recurrent sites of osteosarcomas (n = 3) were treated with high-activity of Sm-153-EDTMP (150 MBq/kg BW). In all patients autologous peripheral blood stem cells had been collected before Sm-153-EDTMP therapy. Results: No immediate adverse reactions were observed in the patients. In one patient bone pain increased during the first 48 hrs after therapy. Three patients received pain relief. Autologous peripheral blood stem cell reinfusion was performed on day +12 to +27 in all patients to overcome potentially irreversible damage to the hematopoietic stem cells. In three patient external radiotherapy of the primary tumor site was performed after Sm-153-EDTMP therapy and in two of them polychemotherapy was continued. Thirty-six months later one of these patients is still free of progression. Two further patients are still alive. However, they have developed new metastases. The three patients who had no accompanying external radiotherapy, all died of disease progression five to 20 months after therapy. Conclusion: These preliminary results show that high-dose Sm-153-EDTMP therapy is feasible and warrants further evaluation of efficacy. The combination with external radiation and polychemotherapy seems to be most promising. Although osteosarcoma is believed to be relatively radioresistant, the total focal dose achieved may delay local progression or even achieve permanent local tumor control in patients with surgically inaccessible primary or relapsing tumors.

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