scholarly journals The Clinical Detection of Scleral Icterus: Observations of Multiple Examiners

1997 ◽  
Vol 162 (8) ◽  
pp. 560-563 ◽  
Author(s):  
Mario A. Ruiz ◽  
Sammy Saab ◽  
Leland S. Rickman
Keyword(s):  
Clinical Detection ◽  
Scleral Icterus

Improving Sensitivity in Clinical Detection of ADL Impairments

2004 ◽  
Author(s):  
S. Fortin ◽  
L. Godbout ◽  
C. M. J. Braun
Keyword(s):  
Clinical Detection

scholarly journals Clinical outcomes and survival analysis in patients with psycho-cardiological disease: a retrospective analysis of 132 cases

2021 ◽  
Vol 49 (3) ◽  
pp. 030006052199098
Author(s):  
Minhua Lai ◽  
Teimei Shen ◽  
Hong Cui ◽  
Lixia Lin ◽  
Peng Ran ◽  
...  
Keyword(s):  
Percutaneous Coronary Intervention ◽  
Total Cholesterol ◽  
Clinical Outcomes ◽  
Detection Rate ◽  
Troponin T ◽  
Coronary Intervention ◽  
Cumulative Survival ◽  
Percutaneous Coronary ◽  
Clinical Detection

Objectives The deleterious effects of psychological problems on coronary heart disease (CHD) are not satisfactorily explained. We explored influential factors associated with mortality in psycho-cardiological disease in a Chinese sample. Methods Of 7460 cardiac patients, we selected 132 patients with CHD and mental illness. Follow-up was conducted via telephone. We analyzed clinical characteristics, clinical outcomes, and survival. Results The clinical detection rate of psycho-cardiological disease in the overall patient population was 1.8%. Of these, 113 patients completed follow-up; 18 died owing to cardiovascular diseases during follow-up. Kaplan–Meier analysis showed dysphagia, limb function, self-care ability, percutaneous coronary intervention, low-density lipoprotein, total cholesterol, pro-brain natriuretic peptide and high-sensitivity (hs) troponin T had significant associations with cumulative survival. Cox regression analysis showed total cholesterol (hazard ratio [HR]: 2.765, 95% confidence interval [CI]: 1.001–7.641), hs troponin T (HR: 4.668, 95% CI: 1.293–16.854), and percutaneous coronary intervention (HR: 3.619, 95% CI: 1.383–9.474) were independently associated with cumulative survival. Conclusions The clinical detection rate of psycho-cardiological disease was far lower than expected. Normal total cholesterol and hs troponin T were associated with reduced cardiovascular disease mortality over 2 years. Percutaneous coronary intervention is a prognostic risk factor in patients with psycho-cardiological disease.

scholarly journals Early diagnosis of frailty; technological and non-intrusive devices for clinical detection

2021 ◽  
pp. 101399
Author(s):  
Francisco Anabitarte-García ◽  
Luis Reyes-Gonzalez ◽  
Luis Rodriguez-Cobo ◽  
Carlos Fernandez-Viadero ◽  
Silvia Somonte-Segares ◽  
...  
Keyword(s):  
Early Diagnosis ◽  
Clinical Detection

scholarly journals Impact of Updated Diagnostic Criteria for Long QT Syndrome on Clinical Detection of Diseased Patients

2016 ◽  
Vol 2 (3) ◽  
pp. 279-287 ◽  
Author(s):  
Kenshi Hayashi ◽  
Tetsuo Konno ◽  
Noboru Fujino ◽  
Hideki Itoh ◽  
Yusuke Fujii ◽  
...  
Keyword(s):  
Diagnostic Criteria ◽  
Long Qt Syndrome ◽  
Long Qt ◽  
Clinical Detection ◽  
Qt Syndrome

scholarly journals Tm-Shift Detection of Dog-Derived Ancylostoma ceylanicum and A. caninum

2018 ◽  
Vol 2018 ◽  
pp. 1-8 ◽  
Author(s):  
Yeqi Fu ◽  
Mingwei Wang ◽  
Xinxin Yan ◽  
Auwalu Yusuf Abdullahi ◽  
Jianxiong Hang ◽  
...  
Keyword(s):  
Ancylostoma Ceylanicum ◽  
Shift Method ◽  
Accuracy Test ◽  
Zoonotic Risk ◽  
Detectable Concentration ◽  
Positive Rate ◽  
Clinical Detection ◽  
Shift Detection ◽  
The Stability ◽  
Detection Effect

To develop a Tm-shift method for detection of dog-derived Ancylostoma ceylanicum and A. caninum, three sets of primers were designed based on three SNPs (ITS71, ITS197, and ITS296) of their internal transcribed spacer 1 (ITS1) sequences. The detection effect of the Tm-shift was assessed through the stability, sensitivity, accuracy test, and clinical detection. The results showed that these three sets of primers could distinguish accurately between A. ceylanicum and A. caninum. The coefficient of variation in their Tm values on the three SNPs was 0.09% and 0.15% (ITS71), 0.18% and 0.14% (ITS197), and 0.13% and 0.07% (ITS296), respectively. The lowest detectable concentration of standard plasmids for A. ceylanicum and A. caninum was 5.33 × 10−6 ng/μL and 5.03 × 10−6 ng/μL. The Tm-shift results of ten DNA samples from the dog-derived hookworms were consistent with their known species. In the clinical detection of 50 fecal samples from stray dogs, the positive rate of hookworm detected by Tm-shift (42%) was significantly higher than that by microscopic examination (34%), and the former can identify the Ancylostoma species. It is concluded that the Tm-shift method is rapid, specific, sensitive, and suitable for the clinical detection and zoonotic risk assessment of the dog-derived hookworm.

scholarly journals Artifacts associated with mithramycin fluorescence in the clinical detection and quantitation of aneuploidy by flow cytometry.

1982 ◽  
Vol 30 (4) ◽  
pp. 317-322 ◽  
Author(s):  
R E Cunningham ◽  
K S Skramstad ◽  
A E Newburger ◽  
S E Shackney
Keyword(s):  
Flow Cytometry ◽  
Room Temperature ◽  
Human Melanoma ◽  
Time Dependent ◽  
Clinical Samples ◽  
Fixation Time ◽  
C Cells ◽  
Temperature Dependent ◽  
Clinical Detection

Ethanol-fixed cells stored at 4 degrees C exhibit fixation time-dependent hyperchromatism in comparison with freshly fixed cells when stained with mithramycin and examined by flow cytometry. This hyperchromatism has been found to be temperature-dependent, developing fully within 72 hr at room temperature, and within 2 hr at 37 degrees C. Cells from normal donors that are stained with mithramycin exhibit spurious aneuploid peaks. These spurious aneuploid peaks can be eliminated by incubating ethanol-fixed cells at 37 degrees C for 2 hr prior to staining; true aneuploidy is not affected by this procedure. In rare instances, cytoplasmic fluorescence can be observed in mithramycin-stained cells. In addition, unexplained hypochromatism and hyperchromatism can be observed in some clinical samples, particularly in human melanoma. The effects of these unexplained staining artifacts can be minimized or eliminated by adopting strict criteria for the clinical detection of aneuploidy by flow cytometry.

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