scholarly journals P1586SARCOPENIA IN HEMODIALYSIS PATIENTS

2020 ◽  
Vol 35 (Supplement_3) ◽  
Author(s):  
Armando Luis Negri ◽  
Ruben Abdala ◽  
Elisa Del Valle ◽  
Pablo Bridoux ◽  
Luciana Gonzalez Paganti ◽  
...  

Abstract Background and Aims Sarcopenia is the loss of skeletal muscle mass and function that occurs with aging. These modifications lead to greater morbidity and mortality as a result of falls, hospitalization, depression and dependence among others. Chronic Kidney disease (CKD) and hemodialysis (HD) produce a favorable environment for the development of sarcopenia. Objective: to study the prevalence of sarcopenia and its different components (muscle mass, strength and physical performance) using EWGSOP 2018 proposed criteria. Method cross-sectional study evaluating 100 adult HD patients. We evaluated: Grip strength (GS) with Jamar Hydraulic Hand Dynamometer (three determinations in the arm without fistula); Appendicular lean mass (ALM) by DXA (GE LUNAR Prodigy Advance) and physical performance: Gait-speed (Time needed to perform a 4-meter walk on a flat surface) and the sit-stand test Results 58 males (M) and 42 females (F). Mean age for M was 54.3 years and 58 years for F. The prevalence of sarcopenia was 18% in the whole group, 10% in M and 20% in F. In M 33% had low GS and 26% low ALM. In M GS correlated with ALM, Albumin and weight p<0.05 (R 2 0.41); ALM correlated with weight r 0.75, height r 0.64 and GS r 0.46 (p<0.05). In F, 27% had low GS, 54% low ALM, and 17% poor physical performance. In F, GS correlated positively with ALM; ALM correlated positively with: weight r 0.78, height r 0.66, GS r 0.59 and sit-stand r 0.40 (p<0.5). Patients with lower grip strength had a higher prevalence of falls in the last year (40% two or more falls) p=0.03. Conclusion A significant proportion of dialysis patients had sarcopenia. Low hand grip strength was associated with a higher prevalence of falls. Recognizing sarcopenia in dialysis patients would allow us to develop strategies to prevent falls and other complications.

2021 ◽  
Author(s):  
Heeyeon Joo ◽  
Jiyoung Hwang ◽  
Jiyeon Kim ◽  
Hyesook Kim ◽  
Oran Kwon

Abstract Background Increased oxidative stress has been shown to lead to muscle damage and reduced physical performance. The antioxidant mechanism is most likely to reduce these relationships, but in the context of the action of carotenoids, more research is needed. This cross-sectional study aims to investigate whether carotenoids modify the association between plasma malondialdehyde (MDA) and physical performance in Korean adolescents. Methods The study sample consisted of 381 participants (164 boys, 217 girls) aged 13−18, who participated in the 2018 National Fitness Award Project. We quantified α-carotene, β-carotene, β-cryptoxanthin, lutein, zeaxanthin, lycopene, and MDA levels in plasma using HPLC with photodiode array detection. Physical performance was measured by determining the absolute and relative hand grip strength, 20-m progressive aerobic cardiovascular endurance run, estimated maximal oxygen consumption, curl-up, and sit-and-reach. Results In boys, the multiple linear regression model adjusted for age, BMI, smoking, drinking, and physical activity showed that the MDA level was negatively associated with absolute hand grip strength; this association was observed only in groups with α-carotene, β-cryptoxanthin, zeaxanthin, and total carotenoid values below the median. Conclusion These results suggest that carotenoids may act as an effect modifier of the association between MDA and physical performance in Korean male adolescents.


2018 ◽  
Vol 14 (3) ◽  
pp. 122
Author(s):  
Amanda Trixie Hardigaloeh ◽  
Rino Alvani Gani ◽  
Irsan Hasan ◽  
Andri Sanityoso Sulaiman

Background: Malnutrition is independent factor related to morbidity, mortality and high cost of treatment in liver cirrhosis. Hand grip strength (HGS) is one of the method use for malnutrition detection and prognosis evaluation. The correlation of HGS with liver function (Child Pugh score) and muscle mass is controversial. These important evaluation is not yet avalaible in Indonesia.Objective: Aim of this study is to assess the role of HGS measurement in malnutrition and its correlation with liver function and muscle mass.Method: This is a cross-sectional study in liver cirrhosis patients at Hepatobiliary Clinic of Cipto Mangunkusumo Hospital from February to June 2015. Nutritional status was assessed by HGS. Muscle mass was obtained from bioimpedance. Data were analyzed using Spearman correlation test.Results: There were 115 patients liver cirrhosis at Hepatobiliary Clinic of Cipto Mangunkusumo Hospital, 112 patients who fit the inclusion criteria, consisted of 79 men and 33 women with mean age 54.15±10.55 years, median Child Pugh score 6 (5-13) with median HGS 26 (11-50) kgF, mean muscle mass 44.43±8.12 kg. The median intake of energy 1334.82 (604.75-3023.7) kkal, median protein 45.87 (19-114.5) gram. Prevalence of malnutrition according HGS was 33%. Hand grip strength is not correlated with Child Pugh score (p=0.046; r=-0.19) however it is correlated with muscle mass (p<0.00; r=0.70).Conclusion: There are 33% malnutrition cases based on HGS in out patient liver cirrhosis. There is no correlation between HGS with Child Pugh score however HGS is correlated with muscle mass in liver cirrhosis.


2020 ◽  
Vol 25 (1) ◽  
Author(s):  
Dalia Mohammed Mosaad ◽  
Amr Almaz Abdel-aziem ◽  
Ghada Ismail Mohamed ◽  
Enas Anwr Abd-Elaty ◽  
Karima Salah Mohammed

2021 ◽  
Vol 18 (1) ◽  
pp. 1-7
Author(s):  
Heidy Heidy ◽  
Tena Djuartina ◽  
Robi Irawan

Introduction: An individual’s overall muscle strength is commonly assessed by a power grip measurement, a reliable indicator of functional capacity and physical condition. The development of muscle parallels the changes of body composition during growth. Aim of this study is to examine the correlationship between hand grip strength and anthropometric. Methods: This cross-sectional study involved 76 male students of Dhammasavana School, aged between 12 – 16 years old, North Jakarta. Hand grip strength was examined using a digital dynamometer on the dominant side. Statistical analysis was computed using SPSS ver. 15.0 program with Spearman correlations test. Significance was set at p<0.05. Results: Dominant hand grip strength was found to have significant (p<0.05 - 0.001) positive correlation with height (r=0.612), lower arm muscle-and-bone cross-sectional circumference and area (CSA) (r=0.553 and r=0.553 respectively), hand length (r=0.548), forearm length (r=0.540), age (r=0.520), weight (r=0.416), and forearm girth (r=0.376). Conclusion: No significant correlation between grip strength and body mass index was found. Positive correlations between the variables mentioned above conclude that the higher the value of the anthropometric measurements, the greater the strength generated in a power grip.


2021 ◽  
pp. 103159
Author(s):  
Reickly D.N. Constansia ◽  
Judith E.K.R. Hentzen ◽  
Carlijn I. Buis ◽  
Joost M. Klaase ◽  
Vincent E. de Meijer ◽  
...  

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Auwal Abdullahi ◽  
Amina Shuaib Bala ◽  
Sani Musa Danazumi ◽  
Saadatu Maiwada Abubakar ◽  
Rislanu Isyaku Adamu ◽  
...  

Abstract Background Pregnancy results in many changes, including reduced hand grip strength (HGS). However, good HGS is required for physical functions such as carrying and breastfeeding the baby after birth. The aim of this study was to determine the factors that may predict HGS during pregnancy. Methods The study was a cross-sectional study approved by the Research Ethics Committees of Kano State Ministry of Health and Aminu Kano Teaching Hospital in Kano, north-west, Nigeria. Pregnant women at the designated hospitals were included in the study if they had no serious comorbidities or any known neurological condition that affects the hands and the neck. Demographic characteristics and independent (predictor) variables (age, weight, height, BMI, maternity leave status, number of full-term deliveries, number of preterm deliveries, number of live births, number of abortuses, gravidity, trimester, systolic blood pressure, diastolic blood pressure, inter arm systolic BP difference [IASBP], inter arm diastolic BP difference [IADBP], and heart rate) of each of the participants were recorded by experienced therapists. The data were analysed using descriptive statistics, t-test, Pearson correlation coefficient and standard multiple regression. Result One hundred and sixty-one pregnant women with mean age, 25.04 ± 4.83 years participated in the study. In the dominant hand, 120 participants (74.5%) had weak grip strength. In the non-dominant hand, 135 participants (83.9%) had weak grip strength. For the dominant hand, the total variance explained by the whole model was significant, 28.5%, F(11, 161) = 1.187, R2 = 0.081, p = 0.300 . In the final model, none of the variables significantly predicted HGS. However, systolic blood pressure contributed to the model more than any other variable (Beta = -0.155). For the non-dominant hand, the total variance explained by the whole model was not significant, 33.1%, F(11, 161) = 1.675, R2 = 0.111, p = 0.089 . In the final model, only systolic blood pressure (Beta = -0.254, p = 0.023) significantly predicted hand grip strength. Conclusion Cardiovascular events or changes during pregnancy (such as change in systolic blood pressure) may be related to HGS in pregnant women. It is therefore, important for clinicians to pay attention to this, in planning rehabilitation strategies for pregnant women.


2021 ◽  
Vol 4 (3Suppl) ◽  
pp. 8-16
Author(s):  
Indra Altankhuyag ◽  
Agiimaa Byambaa ◽  
Anujin Tuvshinjargal ◽  
Anar Bayarmunkh ◽  
Tsolmon Jadamba ◽  
...  

Mongolia ranks third in the world in stroke-related deaths. Loss of skeletal muscle mass and function, known as sarcopenia, is associated with a higher risk of various metabolic disorders such as stroke. Thus, screening of sarcopenia is important. Hand-grip strength (HGS) can be used to predict sarcopenia in the short term. In this cross-sectional study, we used data (n=1180, mean age of 39.2 ± 15.2 and 33.2% males) from the Mon-Timeline cohort study, a multidisciplinary, prospective, population-based cohort study in Mongolia. A digital grip strength dynamometer (TKK 5401 GRIP D; Takei, Japan) was used to measure HGS. We performed binary logistic regression analysis between HGS and stroke risk. Suspected sarcopenia was defined when HGS is less than the 25th percentile of HGS. In this study, 3.3% of all participants had a stroke. The incidence of stroke was significantly higher (5.2% and 1.9%) in people with suspected sarcopenia. According to body composition, the incidence of stroke was more frequent in sarcopenic obese people: 1.3%, 2.4%, 2.8% and 6.2% in normal (non-obese and non-sarcopenic), sarcopenic (non-obese), obese (non-sarcopenic) and sarcopenic obese groups, respectively. In regression analysis, the OR (95% CI) was 2.84 (1.44; 5.59) for sarcopenic compared with non-sarcopenic. The adjustments for age, gender, education, body mass index, waist circumference and hypertensive status attenuated the associations, but lower HGS remained significantly associated with a higher risk of stroke. In conclusion, lower HGS was significantly associated with a higher risk of stroke independent of adiposity and hypertensive status in Mongolian adults.


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