scholarly journals SP798RELATIONS AMONG HYPERURICEMIA,INFLAMMATION, OXIDATIVE STRESS AND ARTERIAL STIFFNESS IN RENAL TRANSPLANT RECIPIENTS

2015 ◽  
Vol 30 (suppl_3) ◽  
pp. iii641-iii642
Author(s):  
Bahar Gurlek Demirci ◽  
Mehtap Erkmen Uyar ◽  
Zeynep Bal ◽  
Emre Tutal ◽  
Fatma NurhanOzdemir Acar ◽  
...  
2013 ◽  
Vol 37 (5) ◽  
pp. 481-490 ◽  
Author(s):  
Marcos Ojeda-Cervantes ◽  
Jonatan Barrera-Chimal ◽  
Josefina Alberú ◽  
Rosalba Pérez-Villalva ◽  
Luis Eduardo Morales-Buenrostro ◽  
...  

2011 ◽  
Vol 18 (10) ◽  
pp. 901-905 ◽  
Author(s):  
Ozkan Gungor ◽  
Fatih Kircelli ◽  
Meltem Sezis Demirci ◽  
Pinar Tuncel ◽  
Ali Riza Sisman ◽  
...  

2019 ◽  
Vol 8 (4) ◽  
pp. 453 ◽  
Author(s):  
Manuela Yepes-Calderón ◽  
Camilo Sotomayor ◽  
António Gomes-Neto ◽  
Rijk Gans ◽  
Stefan Berger ◽  
...  

New-onset diabetes after transplantation (NODAT) is a frequent complication in renal transplant recipients (RTR). Although oxidative stress has been associated with diabetes mellitus, data regarding NODAT are limited. We aimed to prospectively investigate the long-term association between the oxidative stress biomarker malondialdehyde (measured by high-performance liquid chromatography) and NODAT in an extensively phenotyped cohort of non-diabetic RTR with a functioning graft ≥1 year. We included 516 RTR (51 ± 13 years-old, 57% male). Median plasma malondialdehyde (MDA) was 2.55 (IQR, 1.92–3.66) µmol/L. During a median follow-up of 5.3 (IQR, 4.6–6.0) years, 56 (11%) RTR developed NODAT. In Cox proportional-hazards regression analyses, MDA was inversely associated with NODAT, independent of immunosuppressive therapy, transplant-specific covariates, lifestyle, inflammation, and metabolism parameters (HR, 0.55; 95% CI, 0.36–0.83 per 1-SD increase; p < 0.01). Dietary antioxidants intake (e.g., vitamin E, α-lipoic acid, and linoleic acid) were effect-modifiers of the association between MDA and NODAT, with particularly strong inverse associations within the subgroup of RTR with relatively higher dietary antioxidants intake. In conclusion, plasma MDA concentration is inversely and independently associated with long-term risk of NODAT in RTR. Our findings support a potential underrecognized role of oxidative stress in post-transplantation glucose homeostasis.


2014 ◽  
Vol 8 (4) ◽  
pp. 156
Author(s):  
R. Szentimrei ◽  
L. Lőcsey ◽  
I. Seres ◽  
M. Harangi ◽  
D. Kovács ◽  
...  

2020 ◽  
Author(s):  
Zbigniew T. Heleniak ◽  
Sarah Illersperger ◽  
Susanne Brakemeier ◽  
Alicja Dębska-Ślizień ◽  
Paul Bach ◽  
...  

2002 ◽  
Vol 73 (4) ◽  
pp. 663-665 ◽  
Author(s):  
Aboubakr Abdelfatah ◽  
Didier Ducloux ◽  
G??rard Toubin ◽  
G??rard Motte ◽  
Daniel Alber ◽  
...  

Medicine ◽  
2016 ◽  
Vol 95 (6) ◽  
pp. e2819 ◽  
Author(s):  
Lukasz Czyzewski ◽  
Janusz Wyzgal ◽  
Emilia Czyzewska ◽  
Andrzej Kurowski ◽  
Janusz Sierdzinski ◽  
...  

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